Epithelial polarity and tubulogenesis in vitro

Epithelial–mesenchymal transitions in tumour progression

2002 • 6,431 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

Putting tumours in context

2001 • 2,145 citations

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 • 1,176 citations

Morphogenesis of the Polarized Epithelial Cell Phenotype

1989 • 1,087 citations

Origins of Cell Polarity

1996 • 1,024 citations

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

2000 • 913 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

2002 • 772 citations

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

2002 • 763 citations

Spatial and Temporal Regulation of 3-Phosphoinositides by PI 3-Kinase and PTEN Mediates Chemotaxis

2002 • 755 citations

Neurite branching on deformable substrates

2002 • 743 citations

A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

2000 • 740 citations

Tube Morphogenesis

2003 • 657 citations

Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

1998 • 638 citations

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

1998 • 615 citations

Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

1995 • 601 citations

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

1998 • 595 citations

Building epithelial architecture: insights from three-dimensional culture models

2002 • 584 citations

Convergent Extension

2002 • 580 citations

Sec6/8 Complex Is Recruited to Cell–Cell Contacts and Specifies Transport Vesicle Delivery to the Basal-Lateral Membrane in Epithelial Cells

1998 • 523 citations

New Perspectives on Mechanisms Involved in Generating Epithelial Cell Polarity

1999 • 522 citations

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

1991 • 491 citations

Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly

2001 • 444 citations

Integrated activity of PDZ protein complexes regulates epithelial polarity

2002 • 436 citations

Polarity of Epithelial and Neuronal Cells

1992 • 435 citations

Composition and Formation of Intercellular Junctions in Epithelial Cells

2002 • 415 citations

Membrane traffic in polarized epithelial cells

2000 • 384 citations

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization

2002 • 359 citations

Spatio-Temporal Regulation of Rac1 Localization and Lamellipodia Dynamics during Epithelial Cell-Cell Adhesion

2002 • 349 citations

Temporal and Spatial Regulation of Chemotaxis

2002 • 335 citations

Molecular Mechanisms Of Tubulogenesis

2002 • 318 citations

Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros.

1995 • 309 citations

Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish

2000 • 301 citations

Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.

1995 • 301 citations

Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets

2000 • 295 citations

Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass

2002 • 281 citations

Tube or Not Tube

2003 • 264 citations

Deleted in Colorectal Carcinoma and Differentially Expressed Integrins Mediate the Directional Migration of Neural Precursors in the Rostral Migratory Stream

2002 • 242 citations

Role of Rho family GTPases in epithelial morphogenesis

2002 • 238 citations

How to make tubes: signaling by the Met receptor tyrosine kinase

2003 • 236 citations

Dynamic Analysis of Dorsal Closure in Drosophila

2002 • 231 citations

Exocytosis: The Many Masters of the Exocyst

2002 • 230 citations

Morphogenetic Mechanisms of Epithelial Tubulogenesis: MDCK Cell Polarity Is Transiently Rearranged without Loss of Cell–Cell Contact during Scatter Factor/Hepatocyte Growth Factor-Induced Tubulogenesis

1998 • 218 citations

Involvement of Hepatocyte Growth Factor in Kidney Development

1994 • 200 citations

Crumbs interacts with moesin and βHeavy-spectrin in the apical membrane skeleton of Drosophila

2002 • 185 citations

Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway

1993 • 175 citations

An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors

1997 • 161 citations

Exocyst Is Involved in Cystogenesis and Tubulogenesis and Acts by Modulating Synthesis and Delivery of Basolateral Plasma Membrane and Secretory Proteins

2000 • 155 citations

Cell movements during vertebrate development: integrated tissue behaviour versus individual cell migration

2001 • 147 citations

Induction of Terminal Differentiation in Epithelial Cells Requires Polymerization of Hensin by Galectin 3

2000 • 141 citations

Regulation of Programmed Cell Death by Basement Membranes in Embryonic Development

2000 • 139 citations

Epithelial Tube Morphology Is Determined by the Polarized Growth and Delivery of Apical Membrane

2002 • 133 citations

Dynamics of β-Catenin Interactions with APC Protein Regulate Epithelial Tubulogenesis

1997 • 127 citations

Hepatocyte growth factor and the kidney

2002 • 118 citations

Branching Morphogenesis During Kidney Development

2000 • 107 citations

Visualizing muscle cell migration in situ

2000 • 106 citations

Induced Expression of Rnd3 Is Associated with Transformation of Polarized Epithelial Cells by the Raf–MEK–Extracellular Signal-Regulated Kinase Pathway

2000 • 104 citations

Hepatocyte Growth Factor Switches Orientation of Polarity and Mode of Movement during Morphogenesis of Multicellular Epithelial Structures

2003 • 98 citations

Bcl-2 overexpression prevents apoptosis-induced Madin-Darby canine kidney simple epithelial cyst formation

1999 • 85 citations

Tubulogenesis in the developing mammalian kidney

2002 • 80 citations

Pseudomonas aeruginosa ExoT inhibits in vitro lung epithelial wound repair

2001 • 79 citations

The junction between cytokines and cell adhesion

1992 • 76 citations

Hepatocyte Growth Factor Alters the Polarity of Madin-Darby Canine Kidney Cell Monolayers

1997 • 75 citations

Activation of Hepatocyte Growth Factor (HGF) by Endogenous HGF Activator Is Required for Metanephric Kidney Morphogenesis in Vitro

2001 • 53 citations

Galectin-3 and polarized growth within collagen gels of wild-type and ricin-resistant MDCK renal epithelial cells

1999 • 42 citations

Junctions as Organizing Centers in Epithelial Cells? A Fly Perspective

2002 • 34 citations

Ameliorative Effect of Hepatocyte Growth Factor on Glycerol-Induced Acute Renal Failure with Acute Tubular Necrosis

2002 • 29 citations

Analysis of Membrane Traffic in Polarized Epithelial Cells

2001 • 27 citations

Hepatocyte growth factor upregulates α2β1 integrin in Madin-Darby canine kidney cells: Implications in tubulogenesis

2002 • 17 citations

Peering from the outside in: viscoelastic properties of the extracellular matrix dictate spatial organization and apoptosis resistance in mammary epithelial cells

2003 • 2 citations