Postsynaptic CAMP pathway gates early LTP in hippocampal CA1 region

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1990 • 1,627 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

1989 • 1,114 citations

Intracellular injections of EGTA block induction of hippocampal long-term potentiation

1983 • 1,106 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex

1989 • 977 citations

Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

1994 • 959 citations

Inhibition by cAMP of Ras-Dependent Activation of Raf

1993 • 955 citations

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

1993 • 939 citations

Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP

1994 • 889 citations

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices

1990 • 803 citations

Protein Phosphatases: Properties and Role in Cellular Regulation

1983 • 645 citations

Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase.

1983 • 617 citations

Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein

1995 • 615 citations

Mediation of Hippocampal Mossy Fiber Long-Term Potentiation by Cyclic AMP

1994 • 600 citations

Adenylyl cyclases and the interaction between calcium and cAMP signalling

1995 • 594 citations

Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases.

1990 • 589 citations

The Drosophila learning and memory gene rutabaga encodes a - adenylyl cyclase

1992 • 513 citations

The CaM kinase II hypothesis for the storage of synaptic memory

1994 • 510 citations

cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase

1994 • 501 citations

Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.

1994 • 488 citations

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

1991 • 486 citations

Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

1993 • 465 citations

Separation and Characterization of Two Phosphorylase Phosphatase Inhibitors from Rabbit Skeletal Muscle

1976 • 439 citations

Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II

1993 • 437 citations

Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation

1994 • 428 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Protein phosphatases: recent progress.

1991 • 391 citations

CREB: A mediator of long-term memory from mollusks to mammals

1994 • 371 citations

Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

1995 • 341 citations

Potentiated Transmission and Prevention of Further LTP by Increased CaMKII activity in Postsynaptic Hippocampal Slice Neurons

1994 • 330 citations

Release of Adenosine by Activation of NMDA Receptors in the Hippocampus

1994 • 329 citations

Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79.

1992 • 327 citations

Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices

1994 • 320 citations

Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development

1995 • 315 citations

Protein kinase A and hedgehog signaling in drosophila limb development

1995 • 310 citations

Cyclic adenosine 3',5'‐monophosphate mediates beta‐receptor actions of noradrenaline in rat hippocampal pyramidal cells.

1986 • 308 citations

Molecular and functional diversity of mammalian G _s ‐stimulated adenylyl cyclases

1993 • 295 citations

N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus.

1991 • 286 citations

Pka mediates the effects of monoamine transmitters on the K+ current underlying the slow spike frequency adaptation in hippocampal neurons

1993 • 281 citations

Voltage-dependent potentiation of L-type Ca2+ channels due to phosphorylation by cAMP-dependent protein kinase

1993 • 264 citations

Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation

1992 • 258 citations

NMDA Receptor Activation Increases Cyclic AMP in Area CA1 of the Hippocampus via Calcium/Calmodulin Stimulation of Adenylyl Cyclase

1993 • 214 citations

Transcriptional regulation by CREB and its relatives

1993 • 197 citations

Competitive cAMP antagonists for cAMP-receptor proteins.

1984 • 174 citations

Protein kinase A inhibitors prevent the maintenance of hippocampal long-term potentiation

1993 • 169 citations

Regulatory interactions of the calmodulin-binding, inhibitory, and autophosphorylation domains of Ca2+/calmodulin-dependent protein kinase II.

1988 • 159 citations

Hedgehog and beyond

1995 • 149 citations

The role of Ca2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation

1993 • 140 citations

Suppression of Ras-Induced Transformation of NIH 3T3 Cells by Activated Gα _S

1994 • 139 citations

Structure-activity relationship within a series of okadaic acid derivatives

1990 • 139 citations

The postsynaptic density

1993 • 136 citations

Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses.

1995 • 128 citations

Release-enhancing glycine-dependent presynaptic NMDA receptors exist on noradrenergic terminals of hippocampus

1990 • 121 citations

Modulation of synaptic efficacy in field CA1 of the rat hippocampus by forskolin

1992 • 107 citations

Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.

1994 • 98 citations

Active site-directed inhibition of Ca2+/calmodulin-dependent protein kinase type II by a bifunctional calmodulin-binding peptide.

1988 • 94 citations

Inhibition of Endogenous Phosphatase in a Postsynaptic Density Fraction Allows Extensive Phosphorylation of the Major Postsynaptic Density Protein

1993 • 62 citations

Glial localization of adenylate-cyclase-coupled β-adrenoreceptors in rat forebrain slices

1990 • 40 citations

Diastereomers of adenosine 3′,5′‐monothionophosphate (cAMP[S] antagonize the activation of cGMP‐dependent protein kinase

1985 • 21 citations

The cholinergic inhibition of afterhyperpolarization in rat hippocampus is independent of cAMP-dependent protein kinase

1994 • 16 citations

A new microcirculation chamber for inexpensive long-term investigations of nervous tissue in vitro

1986 • 16 citations