Reactive oxygen species-sensitive p38 MAPK controls thrombin-induced migration of vascular smooth muscle cells

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

Novel gp91 ^phox Homologues in Vascular Smooth Muscle Cells

2001 • 841 citations

Oxidant Signaling in Vascular Cell Growth, Death, and Survival

2000 • 742 citations

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

2001 • 487 citations

Plasmin and Matrix Metalloproteinases in Vascular Remodeling

2001 • 436 citations

Vascular Endothelial Growth Factor Upregulates the Expression of Matrix Metalloproteinases in Vascular Smooth Muscle Cells

1998 • 428 citations

Thrombin Activates the Hypoxia-Inducible Factor-1 Signaling Pathway in Vascular Smooth Muscle Cells

2001 • 415 citations

Stimulation of a Vascular Smooth Muscle Cell NAD(P)H Oxidase by Thrombin

1999 • 332 citations

Tumour necrosis factor α activates a p22phox-based NADH oxidase in vascular smooth muscle

1998 • 313 citations

Vascular endothelial groth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: Conversion of prothrombin to thrombin results in progelatininase a activation and cell proliferation

1998 • 274 citations

Rho and Rho Kinase Mediate Thrombin-Stimulated Vascular Smooth Muscle Cell DNA Synthesis and Migration

1999 • 260 citations

Platelet-Derived Growth Factor–Stimulated Superoxide Anion Production Modulates Activation of Transcription Factor NF-κB and Expression of Monocyte Chemoattractant Protein 1 in Human Aortic Smooth Muscle Cells

1997 • 257 citations

Vascular Endothelial Growth Factor-Induced Migration of Vascular Smooth Muscle Cells in Vitro

1999 • 226 citations

On the Mechanism of Thrombin-induced Angiogenesis

1999 • 222 citations

Heparin Blockade of Thrombin-Induced Smooth Muscle Cell Migration Involves Inhibition of Epidermal Growth Factor (EGF) Receptor Transactivation by Heparin-Binding EGF-Like Growth Factor

2000 • 183 citations

Signalling mechanisms in the regulation of vascular cell migration

1995 • 170 citations

Genetic Demonstration of p47phox-Dependent Superoxide Anion Production in Murine Vascular Smooth Muscle Cells

2001 • 128 citations

Vascular Endothelial Growth Factor Enhances Cardiac Allograft Arteriosclerosis

2002 • 125 citations

Thrombin Potently Stimulates Cytokine Production in Human Vascular Smooth Muscle Cells but Not in Mononuclear Phagocytes

1996 • 119 citations

NADPH Oxidase Mediates Tissue Factor–Dependent Surface Procoagulant Activity by Thrombin in Human Vascular Smooth Muscle Cells

2002 • 115 citations

Integrin-Associated Protein Stimulates α2β1-Dependent Chemotaxis via GI-Mediated Inhibition of Adenylate Cyclase and Extracellular-Regulated Kinases

1999 • 111 citations

Regulation of platelet-derived growth factor ligand and receptor gene expression by alpha-thrombin in vascular smooth muscle cells.

1992 • 110 citations

Red Wine Polyphenols Inhibit Vascular Smooth Muscle Cell Migration Through Two Distinct Signaling Pathways

2002 • 109 citations

Reactive Oxygen and NF-κB in VEGF-Induced Migration of Human Vascular Smooth Muscle Cells

2001 • 102 citations

The interface of atherosclerosis and thrombosis: basic mechanisms

1998 • 91 citations

Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for an obligate autocrine mechanism promoting cell proliferation induced by G-protein-coupled receptor agonist.

1996 • 87 citations

Thrombin-Elicited Contractile Responses of Aortic Smooth Muscle

1985 • 86 citations

Thrombin‐induced proliferation and expression of platelet‐derived growth factor‐A chain gene in human vascular smooth muscle cells

1992 • 73 citations

NF‐κB is required for TNF‐α‐directed smooth muscle cell migration

2001 • 68 citations

Tissue Factor Pathway Inhibitor Inhibits Aortic Smooth Muscle Cell Migration Induced by Tissue Factor/Factor VIIa Complex

1997 • 66 citations

Vascular smooth muscle cell migration mediated by thrombin and urokinase receptor

1995 • 59 citations

α-Thrombin Induces Transforming Growth Factor-β<sub>1</sub> mRNA and Protein in Cultured Vascular Smooth Muscle Cells via a Proteolytically Activated Receptor

1997 • 42 citations

The Role of Secondary Growth Factor Production in Thrombin-lnduced Proliferation of Vascular Smooth Muscle Cells

1998 • 39 citations

Thrombin activates p38 mitogen-activated protein kinase in vascular smooth muscle cells

2001 • 33 citations

Regulated expression of PDGF A-chain mRNA in human saphenous vein smooth muscle cells

1991 • 27 citations

ATF-1 Mediates Protease-activated Receptor-1 but Not Receptor Tyrosine Kinase-induced DNA Synthesis in Vascular Smooth Muscle Cells

2002 • 22 citations

Autocrine production of basic fibroblast growth factor translated from novel synthesized mRNA mediates thrombin‐induced mitogenesis in smooth muscle cells

2001 • 16 citations

Stimulation of Human Smooth Muscle Cell Proliferation by Thrombin Involves Increased Synthesis of Platelet-Derived Growth Factor

1998 • 11 citations

α-Thrombin Inhibits Interleukin-6-Induced Stat3 Signaling and gp130 Gene Expression in Primary Cultures of Human Lung Fibroblasts

1999 • 8 citations