Localization of the Death Domain of Tissue Inhibitor of Metalloproteinase-3 to the N Terminus

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

1985 • 702 citations

Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

1994 • 660 citations

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

1994 • 644 citations

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

1997 • 610 citations

TNF‐α converting enzyme (TACE) is inhibited by TIMP‐3

1998 • 604 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Molecular Cloning and Characterization of Human Tissue Inhibitor of Metalloproteinase 4

1996 • 547 citations

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

1994 • 485 citations

Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis.

1998 • 468 citations

Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2)

1994 • 456 citations

Inhibition of Matrix Metalloproteinase Activity Inhibits Smooth Muscle Cell Migration but Not Neointimal Thickening After Arterial Injury

1996 • 307 citations

The Gene Structure of Tissue Inhibitor of Metalloproteinases (TIMP)-3 and Its Inhibitory Activities Define the Distinct TIMP Gene Family

1995 • 295 citations

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3

1999 • 285 citations

Molecular characterization and expression of the gene encoding human erythroid-potentiating activity

1985 • 279 citations

TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis

1998 • 274 citations

Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells.

1998 • 268 citations

Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells

1996 • 253 citations

Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides.

1994 • 250 citations

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A

1993 • 237 citations

Cloning of the cDNA Encoding Human Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) and Mapping of the TIMP3 Gene to Chromosome 22

1994 • 214 citations

Inhibition of Late Vein Graft Neointima Formation in Human and Porcine Models by Adenovirus-Mediated Overexpression of Tissue Inhibitor of Metalloproteinase-3

2000 • 208 citations

cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

1990 • 202 citations

Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes

1991 • 201 citations

Tissue inhibitor of metalloproteinase‐2 (TIMP‐2) has erythroid‐potentiating activity

1992 • 200 citations

Involvement of extracellular-matrix-degrading metalloproteinases in rabbit aortic smooth-muscle cell proliferation

1992 • 190 citations

TIMP-3 INDUCES CELL DEATH BY STABILIZING TNF-α RECEPTORS ON THE SURFACE OF HUMAN COLON CARCINOMA CELLS

1997 • 190 citations

Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1

1995 • 172 citations

The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1

1991 • 164 citations

A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth

1996 • 149 citations

Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.

1992 • 137 citations

Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation

1998 • 128 citations

Human Tissue Inhibitor of Metalloproteinases 3 Interacts with Both the N- and C-terminal Domains of Gelatinases A and B

1999 • 116 citations

Different Domain Interactions Are Involved in the Binding of Tissue Inhibitors of Metalloproteinases to Stromelysin-1 and Gelatinase A

1994 • 77 citations

Development of recombinant adenoviruses that drive high level expression of the human metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 and -2 genes: Characterization of their infection into rabbit smooth muscle cells and human MCF-7 adenocarcinoma cells

1996 • 52 citations

Simple Methods for Preparing Recombinant Adenoviruses for High-Efficiency Transduction of Vascular Cells

2003 • 37 citations

Replacement of Conserved Cysteines in Human Tissue Inhibitor of Metalloproteinases-1

1997 • 32 citations

Vascular Disease: Molecular Biology and Gene Therapy Protocols

2000 • 13 citations