Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2)

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

An improved fluorometric assay for DNA

1971 • 997 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum

1992 • 705 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.

1992 • 502 citations

Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle

1979 • 374 citations

The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity

1991 • 324 citations

A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family.

1992 • 274 citations

Growth Stimulation of Human Keratinocytes by Tissue Inhibitor of Metalloproteinases

1991 • 241 citations

The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins.

1990 • 202 citations

Tissue inhibitor of metalloproteinase‐2 (TIMP‐2) has erythroid‐potentiating activity

1992 • 200 citations

Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2

1991 • 198 citations

Two apparent human endothelial cell growth factors from human hepatoma cells are tumor-associated proteinase inhibitors.

1986 • 196 citations

Purification and Characterization of Two Related but Distinct Metalloproteinase Inhibitors Secreted by Bovine Aortic Endothelial Cells

1989 • 193 citations

Rapid one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinases An application for rheumatoid arthritis serum and plasma

1990 • 176 citations

A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies

1993 • 172 citations

The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1

1991 • 164 citations

A rapid assay method of collagenase activity using 14C-labeled soluble collagen as substrate

1976 • 161 citations

A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 1 (interstitial collagenase) using monoclonal antibodies

1993 • 158 citations

Inhibition of autoproteolytic activation of interstitial procollagenase by recombinant metalloproteinase inhibitor MI/TIMP-2

1991 • 156 citations

Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.

1992 • 137 citations

A one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinases-2 using monoclonal antibodies

1993 • 115 citations

The complex between a tissue inhibitor of metalloproteinases (TIMP‐2) and 72‐kDa progelatinase is a metalloproteinase inhibitor

1991 • 109 citations

K562 cells produce and respond to human erythroid-potentiating activity

1988 • 99 citations

Molecular cloning and nucleotide sequence of human pancreatic secretory trypsin inhibitor (PSTI) cDNA

1985 • 87 citations

Epidermal growth factor: Internal duplication and probable relationship to pancreatic secretory trypsin inhibitor

1974 • 84 citations

TIMP-2, a Growth-Stimulatory Protein from SV40-Transformed Human Fibroblasts

1993 • 75 citations

Characterization of the functional domain of tissue inhibitor of metalloproteinases-2 (TIMP-2)

1993 • 64 citations

Primary amino acid sequence similarity between human epidermal growth factor-urogastrone, human pancreatic secretory trypsin inhibitor, and members of porcine secretin family

1983 • 62 citations

Biology and Function of Tumor-Associated Trypsin Inhibitor, Tati

1991 • 53 citations

Monoclonal Antibodies to Bovine Collagenase Inhibitor

1987 • 48 citations

Efficient Purification of TIMP-2 from Culture Medium Conditioned by Human Hepatoma Cell Line, and Its Inhibitory Effects on Metalloproteinases and In Vitro Tumor Invasion1

1991 • 45 citations

A major retroviral core protein related to EPA and TIMP

1985 • 44 citations

Erythroid potentiating activity of tissue inhibitor of metalloproteinases on the differentiation of erythropoietin-responsive mouse erythroleukemia cell line, ELM-I-1-3, is closely related to its cell growth potentiating activity.

1993 • 41 citations

Cloning and sequencing of the cDNA encoding a mouse tissue inhibitor of metalloproteinase-2

1992 • 39 citations

Identification and characterization of receptors specific for human pancreatic secretory trypsin inhibitor.

1990 • 28 citations

Demonstration of protease activity for epidermal growth factor-binding protein

1980 • 15 citations

<b>SYNTHESIS OF LATENT COLLAGENASE AND COLLAGENASE INHIBITOR BY BOVINE DENTAL PULP FIBROBLAST-LIKE CELLS IN </b><b>CULTURE </b>

1985 • 13 citations

Purification and Characterization of a New Tissue Inhibitor of Metalloproteinases (TIMP-2) from Mouse Colon 26 Tumor Cells

1991 • 11 citations