The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Maturation of the head of bacteriophage T4

1973 • 3,781 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

1985 • 702 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.

1990 • 428 citations

Purification of rabbit bone inhibitor of collagenase

1981 • 352 citations

Pancreatic trypsin inhibitor. 2. Reaction with trypsin

1953 • 292 citations

Primary structure and cDNA cloning of human fibroblast collagenase inhibitor.

1986 • 274 citations

High Level Expression of Tissue Inhibitor of Metalloproteinases in Chinese Hamster Ovary Cells Using Glutamine Synthetase Gene Amplification

1990 • 249 citations

Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase

1989 • 233 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins.

1990 • 202 citations

cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

1990 • 202 citations

Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cells): correlation with rheumatoid arthritis.

1989 • 198 citations

The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis

1990 • 197 citations

Purification and Characterization of Two Related but Distinct Metalloproteinase Inhibitors Secreted by Bovine Aortic Endothelial Cells

1989 • 193 citations

A rapid procedure for preparing fluorescein-labeled specific antibodies from whole antiserum: its use in analyzing cytoskeletal architecture.

1983 • 189 citations

Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP)

1990 • 176 citations

The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor

1983 • 172 citations

An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases

1981 • 171 citations

Immunolocalization of metalloproteinases and their inhibitor in the rabbit growth plate.

1989 • 125 citations

Transin/stromelysin expression in rheumatoid synovium. A transformation-associated metalloproteinase secreted by phenotypically invasive synoviocytes.

1989 • 120 citations

Immunolocalization of tissue inhibitor of metalloproteinases (timp) in human cells characterization and use of a specific antiserum

1985 • 116 citations

Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA

1989 • 114 citations

Immunoassays for the Detection of Human Collagenase, Stromelysin, Tissue Inhibitor of Metallo-proteinases (TIMP) and Enzyme-Inhibitor Complexes

1990 • 95 citations

Transin/stromelysin expression in the synovium of rats with experimental erosive arthritis. In situ localization and kinetics of expression of the transformation-associated metalloproteinase in euthymic and athymic Lewis rats.

1989 • 92 citations

Developmental expression of the endogenous TIMP gene and a TIMP-lacZ fusion gene in transgenic mice.

1990 • 86 citations

Purification to homogeneity of pig leucocyte catabolin, a protein that causes cartilage resorption in vitro

1983 • 81 citations

Vapor‐phase modification of sulfhydryl groups in proteins

1987 • 78 citations

Dissociation of tissue inhibitor of metalloproteinases (TIMP) from enzyme complexes yields fully active inhibitor

1989 • 76 citations

Tissue inhibitor of metalloproteinases (timp) regulates extracellular type i collagen degradation by chondrocytes and endothelial cells

1987 • 74 citations

Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor

1982 • 73 citations

Proteinase Inhibitors

2021 • 73 citations

Role of collagenase in colonic anastomoses: a reappraisal

1988 • 70 citations

Metalloproteinase inhibitors from bovine cartilage and body fluids

1984 • 62 citations

Purification and partial amino acid sequence of a bovine cartilage-derived collagenase inhibitor.

1986 • 61 citations

Identification of a new metalloproteinase inhibitor that forms tight-binding complexes with collagenase

1990 • 34 citations

A High Molecular Weight Collagenase Inhibitor Made by Rabbit Chondrocytes in Cell Culture

1989 • 7 citations

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