Lcb4p Is a Key Regulator of Ceramide Synthesis from Exogenous Long Chain Sphingoid Base in Saccharomyces cerevisiae

The Ceramide-centric Universe of Lipid-mediated Cell Regulation: Stress Encounters of the Lipid Kind

2002 • 895 citations

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

2000 • 654 citations

Sphingosine 1-Phosphate, a Key Cell Signaling Molecule

2002 • 551 citations

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

1998 • 528 citations

Enzymes of Sphingolipid Metabolism: From Modular to Integrative Signaling

2001 • 496 citations

Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ.

1993 • 363 citations

Starvation Induces Vacuolar Targeting and Degradation of the Tryptophan Permease in Yeast

1999 • 289 citations

Lag1p and Lac1p Are Essential for the Acyl-CoA–dependent Ceramide Synthase Reaction inSaccharomyces cerevisae

2001 • 277 citations

C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p

2001 • 277 citations

The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast.

1994 • 260 citations

The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase.

1992 • 258 citations

Sphingoid base 1-phosphate phosphatase: A key regulator of sphingolipid metabolism and stress response

1998 • 244 citations

Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae

2000 • 241 citations

The BST1 Gene of Saccharomyces cerevisiaeIs the Sphingosine-1-phosphate Lyase

1997 • 235 citations

Tsc13p Is Required for Fatty Acid Elongation and Localizes to a Novel Structure at the Nuclear-Vacuolar Interface in Saccharomyces cerevisiae

2001 • 225 citations

The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins.

1993 • 219 citations

Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast

2001 • 205 citations

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

2000 • 195 citations

The LCB4 (YOR171c) and LCB5(YLR260w) Genes of Saccharomyces Encode Sphingoid Long Chain Base Kinases

1998 • 184 citations

The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP.

1995 • 175 citations

Identification of the First Mammalian Sphingosine Phosphate Lyase Gene and Its Functional Expression in Yeast

1998 • 168 citations

Inositol Phosphorylceramide Synthase Is Located in the Golgi Apparatus ofSaccharomyces cerevisiae

2000 • 161 citations

Identification and Characterization of Saccharomyces cerevisiae Dihydrosphingosine-1-phosphate Phosphatase

1997 • 154 citations

Sphingosine kinase: a mediator of vital cellular functions

2001 • 151 citations

Sphingosine 1-phosphate signaling: providing cells with a sense of direction

2002 • 136 citations

Role for de Novo Sphingoid Base Biosynthesis in the Heat-induced Transient Cell Cycle Arrest of Saccharomyces cerevisiae

2001 • 128 citations

Isolation and Characterization of the Saccharomyces cerevisiae DPP1 Gene Encoding Diacylglycerol Pyrophosphate Phosphatase

1998 • 125 citations

Isolation and Characterization of the Saccharomyces cerevisiae LPP1 Gene Encoding a Mg2+-independent Phosphatidate Phosphatase

1998 • 121 citations

The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses

1999 • 114 citations

Two Endoplasmic Reticulum (ER) Membrane Proteins That Facilitate ER-to-Golgi Transport of Glycosylphosphatidylinositol-anchored Proteins

1999 • 109 citations

Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q2211DNA sequence was deposited in the EMBL database (AJ011304).

2000 • 108 citations

Accumulation of Phosphorylated Sphingoid Long Chain Bases Results in Cell Growth Inhibition in Saccharomyces cerevisiae

2000 • 107 citations

Identification of a Saccharomyces Gene,LCB3, Necessary for Incorporation of Exogenous Long Chain Bases into Sphingolipids

1997 • 93 citations

Identification and Characterization of RPK118, a Novel Sphingosine Kinase-1-binding Protein

2002 • 92 citations

Characterization of Murine Sphingosine-1-phosphate Phosphohydrolase

2002 • 86 citations

Cloning and Characterization of a Protein Kinase A Anchoring Protein (AKAP)-related Protein That Interacts with and Regulates Sphingosine Kinase 1 Activity

2002 • 85 citations

Mammalian Mg2+-independent Phosphatidate Phosphatase (PAP2) Displays Diacylglycerol Pyrophosphate Phosphatase Activity

1997 • 85 citations

Segregation of Glycosylphosphatidylinositol Biosynthetic Reactions in a Subcompartment of the Endoplasmic Reticulum

1999 • 65 citations

The ATP-dependent translocation of phosphatidylserine to the mitochondria is a process that is restricted to the autologous organelle.

1993 • 65 citations

The GTP-binding Sar1 protein is localized to the early compartment of the yeast secretory pathway

1991 • 64 citations

Elevation of endogenous sphingolipid long-chain base phosphates kills Saccharomyces cerevisiae cells

2001 • 58 citations

Evidence for the presence of multiple forms of Sph kinase in human platelets

1998 • 54 citations

Mutant analysis reveals complex regulation of sphingolipid long chain base phosphates and long chain bases during heat stress in yeast

2002 • 50 citations

Subcellular study of sphingoid base phosphorylation in rat tissues: evidence for multiple sphingosine kinases

2001 • 41 citations

Lcb4p sphingoid base kinase localizes to the Golgi and late endosomes

2002 • 40 citations

Inhibition of yeast inositol phosphorylceramide synthase by aureobasidin A measured by a fluorometric assay

1999 • 34 citations