Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

Relative expression software tool (REST(C)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

2002 • 7,125 citations

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

2005 • 2,015 citations

Molecular pathogenesis of human hepatocellular carcinoma

2002 • 1,424 citations

Terminology of nodular hepatocellular lesions

1995 • 1,105 citations

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

2006 • 911 citations

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

2004 • 842 citations

Genome‐wide molecular profiles of HCV‐induced dysplasia and hepatocellular carcinoma†

2007 • 675 citations

Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC

2006 • 673 citations

Myc deletion rescues Apc deficiency in the small intestine

2007 • 587 citations

The interplay between MYC and HIF in cancer

2007 • 579 citations

Genomics and Signaling Pathways in Hepatocellular Carcinoma

2007 • 555 citations

The COP9 Signalosome

2003 • 480 citations

Application of comparative functional genomics to identify best-fit mouse models to study human cancer

2004 • 461 citations

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

2005 • 452 citations

Ras Enhances Myc Protein Stability

1999 • 452 citations

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis

2004 • 420 citations

Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes

2002 • 399 citations

Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis

2007 • 397 citations

Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype

2006 • 381 citations

Wnt/Beta-Catenin/Tcf Signaling: A Critical Pathway in Gastrointestinal Tumorigenesis

2002 • 306 citations

Early Hepatocellular Carcinoma and Dysplastic Nodules

2005 • 277 citations

Genetic regulators of large-scale transcriptional signatures in cancer

2006 • 222 citations

Terminology of nodular hepatocellular lesions

1995 • 219 citations

Human prostate cancer precursors and pathobiology

2003 • 206 citations

Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling

2005 • 165 citations

New aspects of diagnosis and therapy of hepatocellular carcinoma

2006 • 157 citations

Conditional transgenic models define how MYC initiates and maintains tumorigenesis

2006 • 144 citations

Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma

2005 • 126 citations

Interspecies comparison of liver carcinogenesis: implications for cancer risk assessment

1997 • 122 citations

Molecular cytogenetic evaluation of virus‐associated and non‐viral hepatocellular carcinoma: analysis of 26 carcinomas and 12 concurrent dysplasias

2000 • 115 citations

Molecular cytogenetic evaluation of virus-associated and non-viral hepatocellular carcinoma: analysis of 26 carcinomas and 12 concurrent dysplasias

2000 • 98 citations

A Tumor Progression Model for Hepatocellular Carcinoma: Bioinformatic Analysis of Genomic Data

2006 • 86 citations

Mutations of β‐catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis

2005 • 73 citations

High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma

2004 • 70 citations

Imaging Diagnosis

2005 • 62 citations

Infrequent point mutations in codons 12 and 61 of ras oncogenes in human hepatocellular carcinomas

1992 • 61 citations

Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis

2006 • 54 citations

Making Myc

2006 • 48 citations

Human Homologue of Maid Is a Useful Marker Protein in Hepatocarcinogenesis

2005 • 23 citations