Molecular cytogenetic evaluation of virus‐associated and non‐viral hepatocellular carcinoma: analysis of 26 carcinomas and 12 concurrent dysplasias

Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors

1992 • 3,344 citations

Hepatitis B virus.The major etiology of hepatocellular carcinoma

1988 • 1,308 citations

Terminology of nodular hepatocellular lesions

1995 • 1,105 citations

Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma

1980 • 610 citations

DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.

1998 • 583 citations

Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples.

1994 • 404 citations

Comprehensive allelotyping of human hepatocellular carcinoma

1997 • 285 citations

Assessment of Genetic Changes in Hepatocellular Carcinoma by Comparative Genomic Hybridization Analysis

1999 • 275 citations

Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

1997 • 274 citations

Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer.

1992 • 269 citations

Hepatitis C-associated hepatocellular carcinoma

1990 • 248 citations

Liver cell dysplasia is a major risk factor for hepatocellular carcinoma in cirrhosis: A prospective study

1995 • 225 citations

Allelotype study of primary hepatocellular carcinoma

1991 • 223 citations

Genetic aberrations detected by comparative genomic hybridization in hepatocellular carcinomas: Their relationship to clinicopathological features

1999 • 215 citations

Prognosis of Primary Hepatocellular Carcinoma

1984 • 212 citations

Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma.

1989 • 191 citations

Cirrhosis and the aetiology of hepatocellular carcinoma

1987 • 178 citations

The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors

1999 • 155 citations

Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas.

1999 • 139 citations

Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype.

1997 • 136 citations

Accumulation of genetic changes during development and progression of hepatocellular carcinoma: Loss of heterozygosity on chromosome arm Ip occurs at an early stage of hepatocarcinogenesis

1995 • 130 citations

Hepatitis B virus integration event in human chromosome 17p near the p53 gene identifies the region of the chromosome commonly deleted in virus-positive hepatocellular carcinomas.

1991 • 128 citations

Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus‐associated hepatocellular carcinoma

1994 • 119 citations

Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization

1999 • 111 citations

Adult cirrhotic liver explants: Precancerous lesions and undetected small hepatocellular carcinomas

1996 • 109 citations

Different pattern of chromosomal allele loss in multiple hepatocellular carcinomas as evidence of their multifocal origin.

1992 • 101 citations

Influence of coexisting cirrhosis on long-term prognosis after surgery in patients with hepatocellular carcinoma.

1992 • 100 citations

Deletion of the E-cadherin gene in hepatitis B virus-positive chinese hepatocellular carcinomas

1993 • 74 citations

Evidence for the presence of two tumour-suppressor genes for hepatocellular carcinoma on chromosome 13q

1995 • 65 citations

Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma

1993 • 63 citations

Frequent multiplication of the long arm of chromosome 8 in hepatocellular carcinoma.

1993 • 60 citations

Nonrandom Cytogenetic Alterations in Hepatocellular Carcinoma from Transgenic Mice Overexpressing c-Myc and Transforming Growth Factor-α in the Liver

1999 • 56 citations

Interphase cytogenetic analysis reveals numerical chromosome aberrations in large liver cell dysplasia

1997 • 46 citations

Chromosomal rearrangements in a primary hepatocellular carcinoma

1990 • 41 citations

Report of a complex karyotype in recurrent metastatic fibrolamellar hepatocellular carcinoma and a review of hepatocellular carcinoma cytogenetics

1996 • 40 citations

Universal linkage system: An improved method for labeling archival DNA for comparative genomic hybridization

1999 • 37 citations

Chromosomal aberrations in hepatocellular carcinomas: Relationship with pathological features

1997 • 36 citations

Chromosome Fragility and Instability in Human Cancer

1994 • 36 citations

Chromosome 1p aberrations are frequent in human primary hepatocellular carcinoma

1996 • 36 citations

Chromosomal aberrations in hepatocellular carcinomas: Relationship with pathological features

1997 • 35 citations

Clinical Oncology A Manual for Students and Doctors Edited and then, revised and enlarged by Members of the "Union Internationale Contre le Cancer (UICC)" Committee, Springer-Verlag, Berlin, Heidelberg, New York, 1978(らいぶらりい)

1980 • 28 citations

Interphase cytogenetics and comparative genomic hybridization of human epithelial cancers and precursor lesions

1997 • 25 citations

Preneoplastic conditions of the liver.

1996 • 23 citations