Myc deletion rescues Apc deficiency in the small intestine

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

Lessons from Hereditary Colorectal Cancer

1996 • 4,900 citations

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

1997 • 3,234 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

2002 • 1,984 citations

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

2004 • 1,483 citations

Caught up in a Wnt storm: Wnt signaling in cancer

2003 • 1,473 citations

A matter of life and death

2002 • 1,251 citations

β-Catenin and TCF Mediate Cell Positioning in the Intestinal Epithelium by Controlling the Expression of EphB/EphrinB

2002 • 1,076 citations

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

2004 • 770 citations

Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression

2002 • 624 citations

Inducible cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of β-catenin

2004 • 328 citations

Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-Myc

2006 • 239 citations

Apoptosis in small intestinal epithelia from p53-null mice: evidence for a delayed, p53-indepdendent G2/M-associated cell death after γ-irradiation

1997 • 211 citations

β-Catenin Regulation during the Cell Cycle: Implications in G2/M and Apoptosis

2003 • 190 citations

c-Myc Is Required for the Formation of Intestinal Crypts but Dispensable for Homeostasis of the Adult Intestinal Epithelium

2005 • 149 citations

c-Myc Overexpression Uncouples DNA Replication from Mitosis

1999 • 128 citations

The Rac Activator Tiam1 Is a Wnt-responsive Gene That Modifies Intestinal Tumor Development

2005 • 115 citations

Cyclin D1 Is Not an Immediate Target of β-Catenin following Apc Loss in the Intestine

2005 • 101 citations

Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells

2005 • 22 citations