A survey of chemicals inducing lipid peroxidation in biological systems

Methods in Enzymology , Vol

1966 • 26,261 citations

Free radicals in biology and medicine

1991 • 17,840 citations

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Free-radical mechanisms in tissue injury

1984 • 1,518 citations

Free-radical chemistry of cigarette smoke and its toxicological implications.

1985 • 1,351 citations

Role of metals in oxygen radical reactions

1985 • 1,149 citations

Carbon Tetrachloride Hepatotoxicity: An Example of Lethal Cleavage

1973 • 729 citations

Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation

1981 • 650 citations

Lipid peroxidation and cellular damage in toxic liver injury.

1985 • 556 citations

Chemicals, Drugs, and Lipid Peroxidation

1976 • 520 citations

Pathological mechanisms in carbon tetrachloride hepatotoxicity

1985 • 422 citations

Free radicals in biology and medicine

1985 • 416 citations

Hepatic lipid peroxidation in vivo in rats with chronic iron overload.

1983 • 399 citations

Overview of enzyme systems involved in bioreduction of drugs and in redox cycling

1986 • 392 citations

Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro.

1984 • 328 citations

Acute paracetamol intoxication of starved mice leads to lipid peroxidation in vivo

1979 • 298 citations

Doxorubicin-dependent lipid peroxidation at low partial pressures of O2

1985 • 272 citations

Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes

1985 • 265 citations

Lipid peroxidation and cellular damage in extrahepatic tissues of bromobenzene-intoxicated mice.

1986 • 264 citations

Effects of cadmium on glutathione peroxidase, superoxide dismutase, and lipid peroxidation in the rat heart: A possible mechanism of cadmium cardiotoxicity

1985 • 246 citations

Drug-induced lipid peroxidation in mice—I Modulation by monooxegenase activity, glutathione and selenium status

1981 • 222 citations

Alcohol ingestion, liver glutathione and lipoperoxidation: Metabolic interrelations and pathological implications

1982 • 215 citations

Consequences of cadmium toxicity in rat hepatocytes: Mitochondrial dysfunction and lipid peroxidation

1986 • 211 citations

Activation of pharmacologic agents to radical intermediates

1982 • 190 citations

Role of reactive oxygen metabolites in crocidolite asbestos toxicity to mouse macrophages.

1986 • 175 citations

Reductive release of iron from ferritin by cation free radicals of paraquat and other bipyridyls.

1986 • 169 citations

Low Level Chemiluminescence of Liver Microsomal Fractions Initiated by tert‐Butyl Hydroperoxide

1982 • 165 citations

Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure

1983 • 160 citations

Lipid peroxidation and haemoglobin degradation in red blood cells exposed to t-butyl hydroperoxide. The relative roles of haem- and glutathione-dependent decomposition of t-butyl hydroperoxide and membrane lipid hydroperoxides in lipid peroxidation and haemolysis

1983 • 153 citations

Role of alcohol dehydrogenase activity and the acetaldehyde in ethanol- induced ethane and pentane production by isolated perfused rat liver

1982 • 146 citations

Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat

1985 • 145 citations

Cocaine-mediated hepatotoxicity a critical review

1984 • 145 citations

CIBA FOUNDATION SYMPOSIUM (NEW SERIES) 46

1977 • 139 citations

In vivo externalization of phosphatidylserine and phosphatidylethanolamine in the membrane bilayer and hypercoagulability by the lipid peroxidation of erythrocytes in rats.

1985 • 138 citations

Cellular toxicity and lipid peroxidation in response to mercury

1982 • 136 citations

Role of redox cycling and lipid peroxidation in bipyridyl herbicide cytotoxicity

1986 • 133 citations

Peroxisome proliferation and lipid peroxidation in rat liver.

1986 • 132 citations

The role of acrolein in allyl alcohol-induced lipid peroxidation and liver cell damage in mice

1987 • 122 citations

Lipid peroxidation: A possible mechanism of cephaloridine-induced nephrotoxicity

1983 • 119 citations

Asbestos-catalysed lipid peroxidation and its inhibition by desferroxamine

1985 • 108 citations

The formation of a novel free radical metabolite from CCl4 in the perfused rat liver and in vivo.

1986 • 108 citations

Biochemical studies on the metabolic activation of halogenated alkanes.

1985 • 105 citations

Effect of antioxidants on lipid peroxidation in iron‐loaded rats

1984 • 104 citations

Effect of zinc pretreatment on mercuric chloride-induced lipid peroxidation in the rat kidney

1984 • 87 citations

Carbon tetrachloride, bromotrichloromethane and ethanol acute intoxication. New chemical evidence for lipid peroxidation in rat tissue microsomes

1983 • 86 citations

Lipid peroxidation as a possible cause of TCDD toxicity

1983 • 81 citations

Biochemical mechanisms of cephaloridine nephrotoxicity: Time and concentration dependence of peroxidative injury

1986 • 81 citations

Potentiation of free radical-induced lipid peroxidative injury to sarcolemmal membranes by lipid amphiphiles.

1986 • 80 citations

Leak formation in human erythrocytes by the radical-forming oxidant t-

1986 • 79 citations

Dose-dependent study of the effects of acute lindane administration on rat liver superoxide anion production, antiooidant enzyme activities and lipid peroxidation

1986 • 79 citations

Is formation of reactive oxygen by cytochrome P-450 perilous and predictable?

1986 • 76 citations

Peroxide-induced membrane damage in human erythrocytes

1985 • 75 citations

Effects of Ferrous Chloride and Iron-Dextran on Lipid Peroxidation in Vivo in Vitamin E and Selenium Adequate and Deficient Rats

1981 • 73 citations

Cephaloridine-induced lipid peroxidation initiated by reactive oxygen species as a possible mechanism of cephaloridine nephrotoxicity

1985 • 73 citations

Effect of gentamicin on lipid peroxidation in rat renal cortex

1985 • 72 citations

The role of lipid peroxidation in the toxicity of foreign compounds to liver cells

1983 • 71 citations

Studies on biochemical effects of nitrogen dioxide

1982 • 70 citations

The role of iron in the paracetamol- and CCl4-induced lipid peroxidation and hepatotoxicity

1985 • 65 citations

Mechanism of hepatotoxicity to periportal regions of the liver lobule due to allyl alcohol: role of oxygen and lipid peroxidation.

1986 • 65 citations

Studies on the biochemical effects of nitrogen dioxide

1984 • 65 citations

Phenylhydrazine-induced lipid peroxidation of red blood cells in vitro and in vivo: Monitoring by the production of volatile hydrocarbons

1984 • 64 citations

Stimulation of lipid peroxidation by methyl mercury in rats

1983 • 63 citations

Redox cycling and lipid peroxidation: The central role of iron chelates

1983 • 61 citations

Influence of vitamin E and nitrogen dioxide on lipid peroxidation in rat lung and liver microsomes

1982 • 61 citations

Vanadium exposure enhances lipid peroxidation in the kidney of rats and mice

1985 • 57 citations

Enhancement of lipid peroxidation in rat liver on acute exposure to styrene and acrylamide a consequence of glutathione depletion

1983 • 55 citations

Free radical-mediated activation of hydrazine derivatives.

1985 • 52 citations

The involvement of iron and lipid peroxidation in the pathogenesis of hcb induced porphyria

1985 • 52 citations

The metabolism of halothane by hepatocytes: A comparison between free radical spin trapping and lipid peroxidation in relation to cell damage

1983 • 51 citations

The vanadate-stimulated oxidation of NAD(P)H by biomembranes is a superoxide-initiated free radical chain reaction

1986 • 49 citations

Hepatic lipid peroxidation and mitochondrial susceptibility to peroxidative attacks during ethanol inhalation and withdrawal

1983 • 48 citations

Mechanism of lipid peroxide formation in polychlorinated biphenyls (PCB) and dichlorodiphenyltrichloroethane (DDT)-poisoned rats

1984 • 47 citations

The mechanism of cumene hydroperoxide-dependent lipid peroxidation: The function of cytochrome P-450

1986 • 47 citations

Lipid peroxidation stimulated by iron nitrilotriacetate in rat liver

1986 • 47 citations

Chemically-induced glutathione depletion and lipid peroxidation

1982 • 47 citations

Reductive-oxygenation mechanism of metabolism of carbon tetrachloride to phosgene by cytochrome P-450.

1984 • 45 citations

Asbestos-induced decomposition of hydrogen peroxide

1985 • 45 citations

Effects of BHA,d-α-tocopherol and retinol acetate on TCDD-mediated changes in lipid peroxidation, glutathione peroxidase activity and survival

1984 • 42 citations

Evidence of enhanced in vivo lipid peroxidation after acute cocaine administration

1983 • 42 citations

The stimulatory effects of asbestos on NADPH-dependent lipid peroxidation in rat liver microsomes

1987 • 40 citations

Effects of vitamin E deficiency and nitrogen dioxide exposure on lung lipid peroxidation: Use of lipid epoxides and malonaldehyde as measures of peroxidation

1982 • 39 citations

Iron content and degree of lipid peroxidation in liver mitochondria isolated from iron-loaded rats

1983 • 38 citations

Prooxidant properties of vanadatein vitroon catecholamines and on lipid peroxidation by mouse and rat tissues

1983 • 38 citations

Glutathione depletion by methyl chloride and association with lipid peroxidation in mice and rats

1984 • 36 citations

Toxicity of 1,2-dibromoethane in isolated hepatocytes: Role of lipid peroxidation

1984 • 34 citations

Effect of prolonged alcohol administration on activities of various enzymes scavenging activated oxygen radicals and lipid peroxide level in the liver of rats

1983 • 33 citations

Haemoglobin denaturation, lipid peroxidation and haemolysis in phenylhydrazine-induced anaemia

1984 • 32 citations

Effect of chronic ethanol consumption on microsomal lipid peroxidation

1986 • 32 citations

Initiation of in vitro lipid peroxidation by N-hydroxynorcocaine and norcocaine nitroxide.

1982 • 31 citations

Effect of vitamin E on pentane exhaled by rats treated with methyl ethyl ketone peroxide

1982 • 30 citations

Lipid Peroxidation in Vivo Monitored as Ethane Exhalation and Malondialdehyde Excretion in Urine after Oral Administration of Chloroform

1986 • 28 citations

Hemolysis caused by polyoxyethylene-derived surfactants evidence for peroxide participation

1981 • 27 citations

Toxicity studies in isolated hepatocytes from selenium-deficient rats and vitamin E-deficient rats

1984 • 27 citations

Breath ethane and pentane as measures of vitamin E protection of Macaca radiata against 90 days of exposure to ozone

1978 • 26 citations

Erythrocytes from ozone-exposed mice exhibit decreased deformability

1985 • 23 citations

A comparison of NADPH and cumene hydroperoxide-stimulated lipid peroxidation in mouse hepatic microsomes

1981 • 22 citations

Ferrous ion-stimulated alkane expiration in rats treated with carbon tetrachloride

1983 • 22 citations

Binding of transferrin‐iron by adriamycin at acidic pH

1986 • 21 citations

Effects of phospholipase a₂inhibitors on diethyl maleate‐induced lipid peroxidation and cellular injury in isolated rat hepatocytes

1982 • 18 citations

Elevated Lipid Peroxidation in Rats Induced by Dietary Lipids and N-Nitrosodimethylamine and its Inhibition by Indomethacin Monitored Via Ethane Exhalation

1987 • 17 citations

Fe2+-supported in vivo lipid peroxidation induced by compounds undergoing redox cycling

1985 • 17 citations

Acute response of rat liver microsomal lipids, lipid peroxidation, and membrane anisotropy to a single oral dose of polybrominated biphenyls

1984 • 16 citations

Formation of ethane in vitro by rat liver homogenates following glutathione depletion in vivo

1983 • 15 citations

Absence of lipid peroxidation as determined by ethane exhalation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)

1985 • 15 citations

Inhibition of ethanol induced ethane exhalation by carcinogenic pretreatment of rats 12 months earlier

1986 • 14 citations

Effect of Clofibrate on Lipid Peroxidation in Rats Treated with Aspirin and 4-Pentenoic Acid1

1987 • 13 citations

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on lipid peroxidation in microsomal systems in vitro

1986 • 13 citations

The effect of iron overload on urinary excretion of immunoreactive prostaglandin E2

1985 • 12 citations

Sex-related differences in NADPH-dependent lipid peroxidation induced by cadmium

1986 • 10 citations

Alterations of the microsomal glucose-6-phosphatase system evoked by ferrous iron- and haloalkane free-radical-mediated lipid peroxidation

1986 • 9 citations

The effect of lung α-tocopherol content on the acute toxicity of nitrogen dioxide

1986 • 9 citations

Ozone and the peroxidation of polyunsaturated fatty acids in vivo

1986 • 6 citations