Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Specificity of a phenobarbital-induced cytochrome P-450 for metabolism of carbon tetrachloride to the trichloromethyl radical

1982 • 182 citations

An Animal Model of Halothane Hepatotoxicity

1979 • 172 citations

Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat

1982 • 167 citations

Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism , , , ,

1980 • 165 citations

Evidence for carbon tetrachloride- and ethanol-induced lipid peroxidation in Vivo demonstrated by ethane production in mice and rats

1977 • 160 citations

Spin-trapping of the trichloromethyl radical produced during enzymic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane

1978 • 155 citations

Protection Against Carbon Tetrachloride-Induced Lipid Peroxidation in the Rat by Dietary Vitamin E, Selenium, and Methionine as Measured by Ethane Evolution

1977 • 148 citations

A carbon-centered free radical intermediate in the prostaglandin synthetase oxidation of arachidonic acid. Spin trapping and oxygen uptake studies.

1980 • 128 citations

Kinetic applications of electron paramagnetic resonance spectroscopy. 31. Rate constants for spin trapping. 1. Primary alkyl radicals

1978 • 114 citations

In vivo spin-trapping of trichloromethyl radicals formed from CCl4

1979 • 106 citations

Selective early loss of polypeptides in liver microsomes of CCl4-treated rats

1982 • 88 citations

Electron Spin Resonance Studies of a Stable Arylnitroso—Olefin Adduct Free Radical¹

1966 • 82 citations

Species differences in carbon tetrachloride-induced hepatotoxicity: The role of CCl4 activation and of lipid peroxidation

1975 • 79 citations

Kinetic applications of electron paramagnetic resonance spectroscopy. 34. Rate constants for spin trapping. 2. Secondary alkyl radicals

1979 • 77 citations

Spin trapping alkylperoxy radicals, and superoxide-alkyl halide reactions

1977 • 72 citations

Characterization of the free radical formed in aerobic microsomal incubations containing carbon tetrachloride and NADPH

1979 • 71 citations

Spin trapping of free radical products of CCI₄ activation using pulse radiolysis and high energy radiation procedures

1980 • 70 citations

In vivo spin-trapping of radicals formed during halothane metabolism

1981 • 64 citations

Evidence for carbon tetrachloride-induced lipid peroxidation in mouse liver

1982 • 45 citations

Effect of drug pretreatment on carbon tetrachloride-induced lipid peroxidation in rat liver microsomal lipids

1970 • 40 citations

A study of the relationships between carbon tetrachloride-induced lipid peroxidation and liver damage in rats pretreated with vitamin E

1974 • 30 citations

Comparison of ethylene dibromide and carbon tetrachloride toxicity in rats and chicks: Blood and liver levels; lipid peroxidation

1972 • 25 citations

Covalent binding of halogenated volatile solvents to subcellular macromolecules in hepatocytes

1981 • 18 citations

Early alterations induced by carbon tetrachloride in the lipids of the membranes of the endoplasmic reticulum of the liver cell II. Distribution of the alterations in the various lipid fractions

1977 • 16 citations

CCI₄-Induced Liver Damage

1964 • 13 citations

Growth and Liver Response of Chicks and Rats to Carbon Tetrachloride and Ethanol

1970 • 10 citations

The Effect of Antioxidants on free Radical Production During IN VIVO Metabolism of Carbon Tetrachloride

1983 • 7 citations

Notizen: Verbesserung der Empfindlichkeit bei der Identifizierung kurzlebiger Radikale durch Spin Trapping mit einem sterisch gehinderten Nitron / Spin Trapping with an Steric Hindered Nitrone

1975 • 6 citations

Kinetic study of the addition of trifluoromethyl radicals to ethylene in hydrocarbon solution

1970 • 5 citations