Enhanced cell survival in fetal hippocampal suspension transplants grafted to adult rat hippocampus following kainate lesions: A three-dimensional graft reconstruction study

Estimation of nuclear population from microtome sections

1946 • 4,378 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

EPILEPSY AND THE TEMPORAL LOBES

1966 • 1,256 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Development of the hippocampal region in the rat I. Neurogenesis examined with ³H‐thymidine autoradiography

1980 • 897 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

Histochemical demonstration of heavy metals

1981 • 758 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension.

1986 • 741 citations

Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

1980 • 672 citations

Kainic acid as a tool for the study of temporal lobe epilepsy

1981 • 584 citations

Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons.

1987 • 495 citations

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

1991 • 462 citations

Brain macrophages: evaluation of microglia and their functions

1992 • 443 citations

Glia are a unique substrate for the in vitro growth of central nervous system neurons

1984 • 425 citations

Mosaic organization of the hippocampal neuroepithelium and the multiple germinal sources of dentate granule cells

1990 • 395 citations

Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity

1983 • 389 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Regulation of Nerve Growth Factor (NGF) Synthesis in the Rat Central Nervous System: Comparison between the Effects of Interleukin‐1 and Various Growth Factors in Astrocyte Cultures and in vivo

1990 • 369 citations

Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats

1992 • 369 citations

Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system

1990 • 308 citations

Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus

1991 • 280 citations

Microglial and Astroglial Reactions to Ischemic and Kainic Acid-Induced Lesions of the Adult Rat Hippocampus

1993 • 266 citations

Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid

1980 • 257 citations

Lesion‐induced sprouting of hippocampal mossy fiber collaterals to the fascia dentata in developing and adult rats

1981 • 232 citations

Cytokine Regulation of Neuronal Survival

1992 • 209 citations

Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines

1992 • 207 citations

Bovine brain astrocytes express basic fibroblast growth factor, a neurotropic and angiogenic mitogen

1988 • 201 citations

Intracerebral grafting: A tool for the neurobiologist

1991 • 195 citations

Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons

1992 • 192 citations

TGF-β1 mRNA Increases in Macrophage/Microglial Cells of the Hippocampus in Response to Deafferentation and Kainic Acid-Induced Neurodegeneration

1993 • 174 citations

Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death

1994 • 167 citations

Regulation by Interleukin‐1 of Nerve Growth Factor Secretion and Nerve Growth Factor mRNA Expression in Rat Primary Astroglial Cultures

1991 • 153 citations

Prospects of transplantation in human neurodegenerative diseases

1991 • 132 citations

Interleukin-6 is elevated in plasma in multiple sclerosis

1991 • 129 citations

Prolonged increases in neurotrophic activity associated with kainate-induced hippocampal synaptic reorganization

1993 • 126 citations

Brain peptides and glial growth. I. Glia-promoting factors as regulators of gliogenesis in the developing and injured central nervous system.

1986 • 104 citations

Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons

1991 • 104 citations

Mossy fibre projections into and out of hippocampal transplants

1983 • 97 citations

Simultaneous immunocytochemical visualization of bromodeoxyuridine and neural tissue antigens.

1991 • 81 citations

Mechanism of nerve growth factor mRNA regulation by interleukin-1 and basic fibroblast growth factor in primary cultures of rat astrocytes.

1991 • 78 citations

Factors influencing structure and function of intracerebral grafts in the mammalian brain: a review

1992 • 75 citations

Selective innervation of embryonic hippocampal transplants by adult host dentate granule cell axons

1991 • 72 citations

Hippocampal neurons transplanted into ischemically lesioned hippocampus: anatomical assessment of survival, maturation and integration

1991 • 71 citations

Microglial and Astrocytic Cell Responses in the Rat Hippocampus after an Intracerebroventricular Kainic Acid Injection

1993 • 68 citations

Chapter 28 Grafting of fetal CA3 neurons to excitotoxic, axon-sparing lesions of the hippocampal CA3 area in adult rats

1990 • 64 citations

Short- and long-term induction of basic fibroblast growth factor gene expression in rat central nervous system following kainate injection

1994 • 63 citations

Secreted peptides as regulators of neuron–glia and glia–glia interactions in the developing nervous system

1988 • 58 citations

A comparative histological and electrophysiological study of some neurotoxins in the rat hippocampus

1982 • 57 citations

Hippocampal neurotrophic factor: Characterization and response to denervation

1986 • 48 citations

Scientific and Ethical Concerns in Neural Fetal Tissue Transplantation

1993 • 39 citations

Quantitative Graft Integration of Fetal Hippocampal Transplants Labeled with 5′ Bromodeoxyuridine into Normal Adult Hippocampus

1994 • 35 citations

Effect of neural transplants on seizure frequency and kindling in immature rats following kainic acid

1991 • 33 citations

Enhanced host perforant path innervation of neonatal dentate tissue after grafting to axon sparing, ibotenic acid lesions in adult rats

1989 • 29 citations

Fluorescent labeling of dissociated fetal cells for tissue culture

1992 • 28 citations

Dynamic alterations in hippocampal morphology following intra-ventricular kainic acid

1984 • 27 citations

Neurosurgical aspects of epilepsy

1992 • 25 citations

Neurosurgical aspects of epilepsy

1991 • 20 citations

Temporal pattern of survival and dendritic growth of fetal hippocampal cells transplanted into ischemic lesions of the adult rat hippocampus

1991 • 19 citations

The use of sodium sulphide-fixed brain tissue for immunocytochemical staining of activated microglia and reactive astrocytes

1993 • 18 citations

Fetal transplants in rat hippocampus following kainic acid lesions: influence of post-lesion delay on graft survival and integration

1994 • 7 citations

The Differentiation of Dentate Granule Cells Following Transplantation

1994 • 5 citations

Survival and maturation of hippocampal suspension grafts.

1991 • 3 citations