Effect of neural transplants on seizure frequency and kindling in immature rats following kainic acid

Biostatistical Analysis

1996 • 36,713 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates

1981 • 683 citations

Open Microsurgical Autograft of Adrenal Medulla to the Right Caudate Nucleus in Two Patients with Intractable Parkinson's Disease

1987 • 676 citations

Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy

1981 • 654 citations

Kainic acid as a tool for the study of temporal lobe epilepsy

1981 • 584 citations

Neural grafting in the mammalian CNS

1985 • 536 citations

The ontogeny of excitatory amino acid receptors in rat forebrain—I.N-methyl-d-aspartate and quisqualate receptors

1990 • 526 citations

Septal transplants restore maze learning in rats with fornix-fimbria lesions

1982 • 414 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Kainic-acid-induced seizures: A developmental study

1984 • 369 citations

The hippocampus: New vistas

1990 • 335 citations

Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions

1982 • 319 citations

Kainic acid seizures in the developing brain: status epilepticus and spontaneous recurrent seizures

1992 • 300 citations

Kainic acid neurotoxicity toward hippocampal formation: Dependence on specific excitatory pathways

1980 • 286 citations

Reformation of the severed septohippocampal cholinergic pathway in the adult rat by transplanted septal neurons

1977 • 264 citations

Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path

1976 • 256 citations

Evidence suggesting secondary epileptogenic lesions after kainic acid: pretreatment with diazepam reduces distant but not local brain damage

1979 • 249 citations

The ontogeny of excitatory amino acid receptors in the rat forebrain—II. Kainic acid receptors

1990 • 216 citations

Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation

1986 • 208 citations

Maturation of kainic acid seizure-brain damage syndrome in the rat. i. clinical, electrographic and metabolic observations

1984 • 207 citations

Reversal of long-term locomotor abnormalities in the kainic acid model of huntington's disease by day 18 fetal striatal implants

1983 • 185 citations

Fetal Brain Transplant: Reduction of Cognitive Deficits in Rats with Frontal Cortex Lesions

1983 • 175 citations

Effects of kainic acid-induced seizures and ischemia on c-fos-like proteins in rat brain

1990 • 175 citations

Functional reinnervation of rat hippocampus by locus coeruleus implants

1979 • 172 citations

Comparative toxicity of kainic acid and other acidic amino acids toward rat hippocampal neurons

1981 • 160 citations

[25] Use of excitatory amino acids to make axon-sparing lesions of hypothalamus

1983 • 150 citations

Anatomical predictors of behavioral recovery following fetal striatal transplants

1986 • 129 citations

Kainic acid‐induced limbic seizures

1981 • 126 citations

Intracephalic embryonic neural implants in the adult rat brain. I. Growth and mature organization of birainstem, cerebellar, and hippocampal implants

1983 • 122 citations

Effects of kainic acid on seizure susceptibility in the developing brain

1988 • 121 citations

Restoration of rhythmic slow activity (θ) in the subcortically denervated hippocampus by fetal CNS transplants

1987 • 117 citations

Transplantation of neural tissues in the brains of laboratory mammals: Technical details and comments

1979 • 113 citations

Transplantation of embryonic neural tissue in the mammalian brain. I. Growth and differentiation of neuroblasts from various regions of the embryonic brain in the cerebellum of neonate rats.

1974 • 104 citations

Acetylcholine-rich neuronal grafts in the forebrain of rats: Effects of environmental enrichment, neonatal noradrenaline depletion, host transplantation site and regional source of embryonic donor cells on graft size and acetylcholinesterase-positive fibre outgrowth

1986 • 103 citations

Cell and tissue transplantation into the adult brain

1987 • 97 citations

Cholinergic reinnervation of the rat hippocampus by septal implants is stimulated by perforant path lesion

1979 • 92 citations

Behavioral and electrographic patterns induced by systemic administration of kainic acid in developing rats

1983 • 92 citations

Neural Tissue Transplantation Research

1983 • 91 citations

Circadian rhythmicity after neural transplant to hamster third ventricle: specificity of suprachiasmatic nuclei

1989 • 89 citations

Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy.

1987 • 88 citations

Neocortical transplants in the cerebellum of the rat: their afferents and efferents

1980 • 86 citations

Behavioral Effects of Kainic Acid Administration on the Immature Brain

1988 • 86 citations

Cortical grafts prevent atrophy of cholinergic basal nucleus neurons induced by excitotoxic cortical damage

1986 • 80 citations

Neural Transplantation in Mammalian Brain: Some Conceptual and Technical Considerations

1983 • 77 citations

Adrenal Medullary Transplantation Into the Brain for Treatment of Parkinson's Disease: Clinical Outcome and Neurochemical Studies

1990 • 76 citations

Behavioral recovery following kainic acid lesions and fetal implants of the striatum occurs independent of dopaminergic mechanisms

1986 • 66 citations

Suppression and induction of epileptic activity by neuronal grafts.

1988 • 65 citations

Efferent fibers from transplanted cerebral cortex of rats

1979 • 65 citations

Intrahippocampal injection of kainic acid produces significant pyramidal cell loss in neonatal rats

1986 • 53 citations

Transplantation of brain tissue in the brain of adult rats

1978 • 52 citations

Fetal brain implants improve maze performance in hippocampal-lesioned rats

1986 • 51 citations

Control of glutamate dehydrogenase in the basidiomycete Schizophyllum commune

1965 • 48 citations

Reformation in adult rats of functional septo-hippocampal connections by septal neurons regenerating across an embryonic hippocampal tissue bridge

1981 • 45 citations

Fetal locus coeruleus transplanted into the transected spinal cord of the adult rat: Some observations and implications

1984 • 38 citations

Kainic Acid Seizures and Neuronal Cell Death: Insights from Studies of Selective Lesions and Drugs

1986 • 30 citations

Extensive target cell loss during development results in mossy fibers in the regio superior (CA1) of the rat hippocampal formation

1985 • 23 citations

Cerebral Transplants for Seizures: Preliminary Results

1988 • 22 citations

On the Role of seizure Activity and Endogenous Excitatory Amino Acids in Mediating Seizure-Associated Hippocampal Damage

1986 • 20 citations

Partial recovery of gustatory function after neurol tissue transplantation to the lesioned gustatory neocortex

1988 • 20 citations

Receptor Characteristics and Behavioral Consequences of Kainic Acid Lesions and Fetal Transplants of the Striatum^a

1987 • 19 citations

Neural grafts attenuate behavioral deficits produced by early radiation-induced hypoplasia of fascia dentata granule cells

1990 • 18 citations

Intrahippocampal cholinergic grafts in aged rats compensate impairments in a radial maze and in a place learning task

1990 • 18 citations

Fetal hypothalamic transplants promote survival and functional regeneration of axotomized adult supraoptic magnocellular neurons

1989 • 17 citations

Stereotaxic technique for transplantation of neural tissues in the brain of adult rats

1982 • 15 citations

The clinical relevance of kindling

1990 • 14 citations

Failure of Neocortical Transplants to Alter Seizure Susceptibility in Previously Kindled Rats

1987 • 9 citations

Deleted Work

1955 • 0 citations