Regulation by Interleukin‐1 of Nerve Growth Factor Secretion and Nerve Growth Factor mRNA Expression in Rat Primary Astroglial Cultures

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

Neuron‐glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electonmicroscopic study in Macacus rhesus

1971 • 1,334 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

1987 • 1,000 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1989 • 692 citations

Characterization and isolation of proteolytically modified nerve growth factor

1976 • 677 citations

Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

1980 • 672 citations

Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein

1960 • 651 citations

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation.

1983 • 564 citations

Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.

1987 • 509 citations

The expression, localization and functional significance of β-nerve growth factor in the central nervous system

1987 • 496 citations

Human β-nerve growth factor gene sequence highly homologous to that of mouse

1983 • 486 citations

Nerve Growth Factor Gene Expression in the Developing Rat Brain

1986 • 436 citations

Glia are a unique substrate for the in vitro growth of central nervous system neurons

1984 • 425 citations

In vitro neurite extension by granule neurons is dependent upon astroglial-derived fibroblast growth factor

1988 • 408 citations

Expression of the β-Nerve Growth Factor Gene in Hippocampal Neurons

1988 • 356 citations

EXCESSIVE GROWTH OF THE SYMPATHETIC GANGLIA EVOKED BY A PROTEIN ISOLATED FROM MOUSE SALIVARY GLANDS

1960 • 351 citations

Gene expression in rat brain

1983 • 344 citations

Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell. Intracellular storage, proteolytic processing, and secretion on stimulation

1983 • 329 citations

Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts.

1988 • 244 citations

Purification of two astroglial growth factors from bovine brain

1985 • 235 citations

Astrocytes are important for sprouting in the septohippocampal circuit

1988 • 230 citations

Astrocytes

1989 • 227 citations

Insulin-like growth factor I receptors in neuronal and glial cells. Characterization and biological effects in primary culture.

1987 • 190 citations

Interleukin‐1‐like activity in rat brain: Sources, targets, and effects of injury

1987 • 180 citations

Novel Neurotrophic Factors, Receptors, and Oncogenes

1989 • 152 citations

Synthesis/secretion of nerve growth factor is associated with cell growth in cultured mouse astroglial cells

1987 • 117 citations

Effects of nerve growth factor on cholinergic brain neurons

1989 • 112 citations

The Cycling of Calcium as an Intracellular Messenger

1989 • 110 citations

Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector.

1988 • 110 citations

Growth Control of the Sympathetic System by a Specific Protein Factor

1961 • 108 citations

Characterization of somatomedin/insulin-like growth factor receptors and correlation with biologic action in cultured neonatal rat astroglial cells

1987 • 107 citations

Differentiating effects of murine nerve growth factor in the peripheral and central nervous systems of Xenopus laevis tadpoles.

1985 • 76 citations

Fibroblast interleukin 1 beta: synergistic stimulation by recombinant interleukin 1 and tumor necrosis factor and posttranscriptional regulation.

1989 • 70 citations

Increase in nerve growth factor content of C6 glioma cells by the activation of a β-adrenergic receptor

1977 • 68 citations

Characterization of Epidermal Growth Factor Receptors in Astrocytic Glial and Neuronal Cells in Primary Culture*

1989 • 49 citations

Dichotomy of the glial cell response to axonal injury and regeneration

1989 • 45 citations

Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells.

1988 • 44 citations