Complement: a novel factor in basal and ischemia-induced neurogenesis

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Mammalian Neural Stem Cells

2000 • 4,689 citations

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

1999 • 3,822 citations

CNS stem cells express a new class of intermediate filament protein

1990 • 3,138 citations

Neuronal replacement from endogenous precursors in the adult brain after stroke

2002 • 2,731 citations

Neurogenesis in Adult Subventricular Zone

2002 • 1,415 citations

The Adult Rat Hippocampus Contains Primordial Neural Stem Cells

1997 • 1,080 citations

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway

2004 • 1,045 citations

Rat forebrain neurogenesis and striatal neuron replacement after focal stroke

2002 • 1,013 citations

Fibroblast Growth Factor-2 Activates a Latent Neurogenic Program in Neural Stem Cells from Diverse Regions of the Adult CNS

1999 • 916 citations

Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia

1998 • 899 citations

Oligodendrocyte Precursor Cells Reprogrammed to Become Multipotential CNS Stem Cells

2000 • 869 citations

The glial identity of neural stem cells

2003 • 710 citations

Neuronal fate determinants of adult olfactory bulb neurogenesis

2005 • 602 citations

Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum

2003 • 510 citations

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

2002 • 434 citations

Doublecortin expression in the adult rat telencephalon

2001 • 422 citations

Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion

1996 • 422 citations

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1 alpha/CXC chemokine receptor 4 pathway

2004 • 416 citations

The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration

2003 • 413 citations

Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures

1999 • 411 citations

bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

2004 • 404 citations

Adult-generated hippocampal and neocortical neurons in macaques have a transient existence

2001 • 394 citations

The C5a chemoattractant receptor mediates mucosal defence to infection

1996 • 345 citations

Inflammatory Signals Induce Neurotrophin Expression in Human Microglial Cells

1998 • 285 citations

Cyclin-dependent kinases as a therapeutic target for stroke

2000 • 276 citations

Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6

2004 • 268 citations

A Novel Role of Complement: Mice Deficient in the Fifth Component of Complement (C5) Exhibit Impaired Liver Regeneration

2001 • 249 citations

Neuronal apoptosis at the G1/S cell cycle checkpoint

2001 • 236 citations

Mild Cerebral Ischemia Induces Loss of Cyclin-Dependent Kinase Inhibitors and Activation of Cell Cycle Machinery before Delayed Neuronal Cell Death

2001 • 225 citations

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

2003 • 224 citations

Activation of Complement in the Central Nervous System

2003 • 222 citations

Generation of C5a by Phagocytic Cells

2002 • 210 citations

Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models

2001 • 194 citations

The Newt Ortholog of CD59 Is Implicated in Proximodistal Identity during Amphibian Limb Regeneration

2002 • 191 citations

Cutting Edge: Targeted Disruption of the C3a Receptor Gene Demonstrates a Novel Protective Anti-Inflammatory Role for C3a in Endotoxin-Shock

2000 • 187 citations

Complement anaphylatoxin receptors on neurons: new tricks for old receptors?

1999 • 174 citations

Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

2003 • 172 citations

Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells

1999 • 153 citations

The Role of the Complement Cascade in Ischemia/Reperfusion Injury: Implications for Neuroprotection

2001 • 151 citations

Expression of Receptors for Complement Anaphylatoxins C3a and C5a Following Permanent Focal Cerebral Ischemia in the Mouse

2000 • 150 citations

Neuronal Expression of a Functional Receptor for the C5a Complement Activation Fragment

2001 • 149 citations

Expression of Complement 3 and Complement 5 in Newt Limb and Lens Regeneration

2003 • 146 citations

Characterization of Complement Anaphylatoxins and Their Biological Responses

1998 • 143 citations

Effect of Lactacidosis on Pyridine Nucleotide Stability During Ischemia in Mouse Brain

1987 • 140 citations

Expression of a complete and functional complement system by human neuronal cells in vitro

2000 • 135 citations

Attenuation of Experimental Autoimmune Demyelination in Complement-Deficient Mice

2000 • 129 citations

Neuroprotection by Complement (C1) Inhibitor in Mouse Transient Brain Ischemia

2003 • 120 citations

Complement anaphylatoxin C5a neuroprotects through mitogen‐activated protein kinase‐dependent inhibition of caspase 3

2001 • 115 citations

Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death

2001 • 109 citations

Expression of the Third Component of Complement, C3, in Regenerating Limb Blastema Cells of Urodeles

1998 • 104 citations

Anti-C5a receptor antibodies. Characterization of neutralizing antibodies specific for a peptide, C5aR-(9-29), derived from the predicted amino-terminal sequence of the human C5a receptor.

1993 • 95 citations

Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry

2002 • 89 citations

Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody

2003 • 73 citations

Experimental diffuse axonal injury induces enhanced neuronal C5a receptor mRNA expression in rats

1997 • 72 citations

Expression of a Functional C5a Receptor in Regenerating Hepatocytes and Its Involvement in a Proliferative Signaling Pathway in Rat

2004 • 59 citations

Complement C3a Enhances CXCL12 (SDF-1)-Mediated Chemotaxis of Bone Marrow Hematopoietic Cells Independently of C3a Receptor

2005 • 50 citations

Protective Effect of C1 Esterase Inhibitor on Reperfusion Injury in the Rat Middle Cerebral Artery Occlusion Model

2003 • 50 citations

INDUCTION OF DNA SYNTHESIS IN CULTURED NEURONS BY ULTRAVIOLET LIGHT OR METHYL METHANE SULFONATE

1972 • 45 citations

Expression of the anaphylatoxin C5a receptor in the oligodendrocyte lineage

2001 • 43 citations

Oedema and glial cell involvement in the aged mouse brain after permanent focal ischaemia

2000 • 29 citations

Targeted Disruption of the Murine Gene Coding for the Third Complement Component (C3)

1998 • 26 citations

Strategies for Inhibition of Complement Activation in the Treatment of Neurodegenerative Diseases

1998 • 18 citations