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Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway

Data up to Jan 2025

Published2004
Citations1,045
References46

Total Citations Per Year

Abstract

References (46)

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

2003 • 2,295 citations

Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4

1999 • 1,714 citations

Chain Migration of Neuronal Precursors

1996 • 1,312 citations

SOX2 Functions to Maintain Neural Progenitor Identity

2003 • 1,284 citations

Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas

2000 • 1,202 citations

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

2003 • 1,059 citations

CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

2001 • 1,024 citations

doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein

1998 • 1,019 citations

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

2002 • 954 citations

Biological Progression from Adult Bone Marrow to Mononucleate Muscle Stem Cell to Multinucleate Muscle Fiber in Response to Injury

2002 • 800 citations

Engraftable human neural stem cells respond to development cues, replace neurons, and express foreign genes

1998 • 776 citations

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

2003 • 755 citations

Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex

2004 • 616 citations

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

2003 • 611 citations

Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

2000 • 606 citations

The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue

2002 • 554 citations

Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone

2000 • 476 citations

JNK phosphorylates paxillin and regulates cell migration

2003 • 461 citations

Long-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease

1997 • 449 citations

Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex

1997 • 439 citations

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

2002 • 413 citations

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

2003 • 378 citations

CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival

2002 • 369 citations

Fractal geometry predicts varying body size scaling relationships for mammal and bird home ranges

2002 • 341 citations

p38 and ERK1/2 Coordinate Cellular Migration and Proliferation in Epithelial Wound Healing

2003 • 333 citations

Neural precursor cell chain migration and division are regulated through different β1 integrins

1998 • 265 citations

Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons

2002 • 238 citations

Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury

2004 • 235 citations

Segregation of Human Neural Stem Cells in the Developing Primate Forebrain

2001 • 228 citations

c-Jun Is Essential for Organization of the Epidermal Leading Edge

2003 • 221 citations

Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells

2004 • 216 citations

Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury

2004 • 214 citations

Mechanism of Human Stem Cell Migration and Repopulation of NOD/SCID and B2mnull NOD/SCID Mice

2001 • 189 citations

Diverse Transcriptional Response of CD4+ T Cells to Stromal Cell-Derived Factor (SDF)-1: Cell Survival Promotion and Priming Effects of SDF-1 on CD4+ T Cells

2001 • 175 citations

Stromal cell‐derived factor 1‐mediated CXCR4 signaling in rat and human cortical neural progenitor cells

2004 • 152 citations

Global gene and cell replacement strategies via stem cells

2002 • 148 citations

Nasal Vaccination with Myelin Oligodendrocyte Glycoprotein Reduces Stroke Size by Inducing IL-10-Producing CD4+ T Cells

2003 • 143 citations

The organization of the visual cortex in the cat.

1955 • 135 citations

Emx2regulates the proliferation of stem cells of the adult mammalian central nervous system

2002 • 131 citations

Role of p38 Mitogen-Activated Protein Kinase in Chemokine-Induced Emigration and Chemotaxis In Vivo

2001 • 123 citations

Involvement of p90 in Neurite Outgrowth Mediated by the Cell Adhesion Molecule L1

1996 • 108 citations

Neural Stem/Progenitor Cells Express Costimulatory Molecules That Are Differentially Regulated by Inflammatory and Apoptotic Stimuli

2004 • 89 citations

p21-activated kinase 1 participates in tracheal smooth muscle cell migration by signaling to p38 MAPK

2001 • 89 citations

Stem cells: cross–talk and developmental programs

2004 • 53 citations

Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis

2003 • 42 citations

Fractal Branching Pattern in the Pial Vasculature in the Cat

2001 • 40 citations

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