Roles for GFRα1 receptors in zebrafish enteric nervous system development

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Physiology of the Gastrointestinal Tract

2006 • 4,704 citations

Effective targeted gene ‘knockdown’ in zebrafish

2000 • 2,464 citations

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

1994 • 1,589 citations

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 • 1,261 citations

Renal and neuronal abnormalities in mice lacking GDNF

1996 • 1,260 citations

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

1996 • 1,208 citations

GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF

1996 • 1,170 citations

Defects in enteric innervation and kidney development in mice lacking GDNF

1996 • 1,169 citations

The Enteric Nervous System

2016 • 1,113 citations

Characterization of a multicomponent receptor for GDNF

1996 • 1,086 citations

Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

1993 • 892 citations

The migration of neural crest cells to the wall of the digestive tract in avian embryo

1973 • 824 citations

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

1996 • 711 citations

Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons.

1995 • 595 citations

Artemin, a Novel Member of the GDNF Ligand Family, Supports Peripheral and Central Neurons and Signals through the GFRα3–RET Receptor Complex

1998 • 578 citations

GFRα1 Is an Essential Receptor Component for GDNF in the Developing Nervous System and Kidney

1998 • 550 citations

Organization of hindbrain segments in the zebrafish embryo

1990 • 516 citations

[24] Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: Thermal race

1993 • 501 citations

Persephin, a Novel Neurotrophic Factor Related to GDNF and Neurturin

1998 • 499 citations

Hu neuronal proteins are expressed in proliferating neurogenic cells

1994 • 479 citations

Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function

1998 • 472 citations

GDNF Family Neurotrophic Factor Signaling: Four Masters, One Servant?

1999 • 469 citations

GFRα1-Deficient Mice Have Deficits in the Enteric Nervous System and Kidneys

1998 • 463 citations

Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts

1996 • 409 citations

A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor

1997 • 397 citations

GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo

1995 • 367 citations

Expression of Neurturin, GDNF, and GDNF Family-Receptor mRNA in the Developing and Mature Mouse

1999 • 366 citations

TrnR2, a Novel Receptor That Mediates Neurturin and GDNF Signaling through Ret

1997 • 357 citations

The sacral neural crest contributes neurons and glia to the post-umbilical gut: spatiotemporal analysis of the development of the enteric nervous system

1998 • 346 citations

Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump.

1988 • 320 citations

Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis

2002 • 313 citations

GDNF Is a Chemoattractant for Enteric Neural Cells

2001 • 307 citations

Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins

1997 • 302 citations

Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase

1997 • 300 citations

Organization of the lateral line system in embryonic zebrafish

2000 • 284 citations

Retarded Growth and Deficits in the Enteric and Parasympathetic Nervous System in Mice Lacking GFRα2, a Functional Neurturin Receptor

1999 • 283 citations

Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo

2001 • 269 citations

Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system

1999 • 265 citations

GDNF availability determines enteric neuron number by controlling precursor proliferation

2003 • 260 citations

Neurturin and Glial Cell Line-Derived Neurotrophic Factor Receptor-β (GDNFR-β), Novel Proteins Related to GDNF and GDNFR-α with Specific Cellular Patterns of Expression Suggesting Roles in the Developing and Adult Nervous System and in Peripheral Organs

1997 • 256 citations

Genetics of Hirschsprung disease

2000 • 255 citations

GFRα-2 and GFRα-3 Are Two New Receptors for Ligands of the GDNF Family

1997 • 229 citations

Neurturin and GDNF Promote Proliferation and Survival of Enteric Neuron and Glial Progenitorsin Vitro

1998 • 228 citations

GDNF and ET-3 Differentially Modulate the Numbers of Avian Enteric Neural Crest Cells and Enteric Neuronsin Vitro

1998 • 227 citations

Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons

1997 • 226 citations

Ontogenetic appearance and disappearance of tyrosine hydroxylase and catecholamines in the rat embryo.

1978 • 225 citations

Mutations in the Zebrafish Unmask Shared Regulatory Pathways Controlling the Development of Catecholaminergic Neurons

1999 • 214 citations

Enteric Nervous System: Development and Developmental Disturbances—Part 1

2002 • 203 citations

Enteric Nervous System: Development and Developmental Disturbances—Part 2

2002 • 202 citations

Appearance of catecholamine-synthesizing enzymes during development of rat sympathetic nervous system: Possible role of tissue environment

1979 • 189 citations

Multiple GPI-Anchored Receptors Control GDNF-Dependent and Independent Activation of the c-Ret Receptor Tyrosine Kinase

1998 • 188 citations

Vital dye labelling demonstrates a sacral neural crest contribution to the enteric nervous system of chick and mouse embryos

1991 • 177 citations

Age-Dependent Differences in the Effects of GDNF and NT-3 on the Development of Neurons and Glia from Neural Crest-Derived Precursors Immunoselected from the Fetal Rat Gut: Expression of GFRα-1in Vitroandin Vivo

1998 • 175 citations

The teleostean forebrain: a comparative and developmental view based on early proliferation, Pax6 activity and catecholaminergic organization

2002 • 172 citations

Enteric neural crest-derived cells: Origin, identification, migration, and differentiation

2001 • 166 citations

Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells.

1995 • 161 citations

Expression and regulation of GFRα3, a glial cell line-derived neurotrophic factor family receptor

1998 • 150 citations

Colonization of the post-umbilical bowel by cells derived from the sacral neural crest: direct tracing of cell migration using an intercalating probe and a replication-deficient retrovirus

1991 • 144 citations

Glial cell line‐derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomic ganglia

1995 • 133 citations

GFRα3 is an orphan member of the GDNF/neurturin/persephin receptor family

1998 • 132 citations

Genes dependent on zebrafishcyclops function identified by AFLP differential gene expression screen

2000 • 112 citations

Pathfinding by Identified Zebrafish Motoneurons in the Absence of Muscle Pioneers

1997 • 109 citations

Identification and Characterization of GFRα-3, a Novel Co-receptor Belonging to the Glial Cell Line-derived Neurotrophic Receptor Family

1998 • 105 citations

Developmental regulation of GDNF response and receptor expression in the enteric nervous system

2000 • 97 citations

GFRα-4, a New GDNF Family Receptor

1998 • 94 citations

Functional Analysis of Zebrafish GDNF

2001 • 82 citations

Hirschsprung Disease and Other Enteric Dysganglionoses

1999 • 72 citations

An Oligonucleotide Fingerprint Normalized and Expressed Sequence Tag Characterized Zebrafish cDNA Library

2001 • 70 citations

Expression of ret in the chicken embryo suggests roles in regionalisation of the vagal neural tube and somites and in development of multiple neural crest and placodal lineages

1995 • 68 citations

Mammalian GFRα-4, a Divergent Member of the GFRα Family of Coreceptors for Glial Cell Line-derived Neurotrophic Factor Family Ligands, Is a Receptor for the Neurotrophic Factor Persephin

2000 • 61 citations

Expression Pattern of GDNF, c-ret, and GFRαs Suggests Novel Roles for GDNF Ligands during Early Organogenesis in the Chick Embryo

2000 • 50 citations