Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Nerve growth factor.

1968 • 2,025 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 • 1,261 citations

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1995 • 1,084 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

The changing scene of neurotrophic factors

1991 • 827 citations

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

1995 • 686 citations

Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve.

1993 • 685 citations

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1995 • 659 citations

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1989 • 624 citations

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1995 • 593 citations

The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor

1989 • 557 citations

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II

1990 • 529 citations

Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons.

1987 • 495 citations

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

1991 • 462 citations

Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF)

1989 • 429 citations

Arrest of Motor Neuron Disease in wobbler Mice Cotreated with CNTF and BDNF

1994 • 389 citations

Glial Cell Line-Derived Neurotrophic Factor Is Expressed in the Developing but Not Adult Striatum and Stimulates Developing Dopamine Neurons in Vivo

1993 • 384 citations

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin.

1994 • 377 citations

Cloning and sequence analysis of a cDNA encoding rat preprocholecystokinin.

1984 • 355 citations

TGF-β receptors and actions

1994 • 291 citations

Sympathetic neuroblasts undergo a developmental switch in trophic dependence

1993 • 279 citations

Members of several gene families influence survival of rat motoneurons in vitro and in vivo

1993 • 274 citations

Regional and Cell-Specific Expression of GDNF in Rat Brain

1993 • 272 citations

Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis.

1992 • 265 citations

Leukemia inhibitory factor mediates an injury response but not a target-directed developmental transmitter switch in sympathetic neurons

1993 • 244 citations

Nucleotide sequence divergence and functional constraint in VIP precursor mRNA evolution between human and rat

1985 • 222 citations

Rat pre-prosomatostatin. Structure and processing by microsomal membranes.

1983 • 218 citations

NT-3 stimulates sympathetic neuroblast proliferation by promoting precursor survival

1993 • 218 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

Expression of GDNF mRNA in Rat and Human Nervous Tissue

1994 • 192 citations

Purification and Initial Characterization of Rat B49 Glial Cell Line‐Derived Neurotrophic Factor

1994 • 189 citations

Murine osteogenic protein (OP-1): High levels of mRNA in kidney

1991 • 184 citations

Neuropoietic cytokines and activin A differentially regulate the phenotype of cultured sympathetic neurons.

1994 • 167 citations

Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger rna in response to kainate-induced excitation

1994 • 156 citations

Two different signal transduction pathways can be activated by transforming growth factor beta 1 in epithelial cells.

1994 • 151 citations

Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain

1993 • 146 citations

Insulin-like growth factor II stimulates motor nerve regeneration.

1992 • 141 citations

Sequence analysis of cloned cDNA for rat substance P precursor: Existence of a third substance P precursor

1986 • 137 citations

Mesencephalic type I astrocytes mediate the survival of substantia nigra dopaminergic neurons in culture

1992 • 128 citations

Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4.

1994 • 116 citations

Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion

1993 • 106 citations

CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons

1994 • 92 citations

Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons

1993 • 79 citations

Perspectives in andrology

1990 • 74 citations

Type I Receptors Specify Growth-Inhibitory and Transcriptional Responses to Transforming Growth Factor β and Activin

1994 • 70 citations

Coordinate Regulation of Choline Acetyltransferase, Tyrosine Hydroxylase, and Neuropeptide mRNAs by Ciliary Neurotrophic Factor and Leukemia Inhibitory Factor in Cultured Sympathetic Neurons

1994 • 68 citations

Role and expression of neurotrophins and the trk family of tyrosine kinase receptors in neural growth and rescue after injury.

1993 • 53 citations

Cholinergic Neuronotrophic Factors. Concurrent Activities on Certain Nerve Growth Factor‐Responsive Neurons

1982 • 36 citations

Selective modulation of cholinergic properties in cultures of avian embryonic sympathetic ganglia

1993 • 13 citations