Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4

Basic local alignment search tool

1990 • 87,358 citations

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

A family of cytokine-inducible inhibitors of signalling

1997 • 2,055 citations

A new protein containing an SH2 domain that inhibits JAK kinases

1997 • 1,413 citations

Structure and function of a new STAT-induced STAT inhibitor

1997 • 1,308 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.

1995 • 761 citations

Twenty proteins containing a C-terminal SOCS box form five structural classes

1998 • 735 citations

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

1999 • 620 citations

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

1998 • 596 citations

Structure of the p53 Tumor Suppressor Bound to the Ankyrin and SH3 Domains of 53BP2

1996 • 569 citations

The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

1998 • 563 citations

Hundreds of ankyrin‐like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally?

1993 • 504 citations

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

1999 • 428 citations

Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila

1987 • 366 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA

1998 • 287 citations

Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.

1994 • 275 citations

Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

1998 • 246 citations

A First-Generation Whole Genome–Radiation Hybrid Map Spanning the Mouse Genome

1997 • 181 citations

cDNA sequence for human erythrocyte ankyrin.

1990 • 166 citations

Tumor Suppressor p16INK4A: Determination of Solution Structure and Analyses of Its Interaction with Cyclin-Dependent Kinase 4

1998 • 157 citations

Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity.

1995 • 154 citations

Black widow spider toxins: the present and the future

1998 • 113 citations

Activation of SOCS-3 Messenger Ribonucleic Acid in the Hypothalamus by Ciliary Neurotrophic Factor¹

1999 • 103 citations

Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta

1999 • 102 citations

Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations

1998 • 87 citations

Tumor Suppressor p16^INK4A: Structural Characterization of Wild-Type and Mutant Proteins by NMR and Circular Dichroism

1996 • 75 citations

Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a

1998 • 52 citations

Tumor Suppressor INK4: Determination of the Solution Structure of p18^INK4C and Demonstration of the Functional Significance of Loops in p18^INK4C and p16^{INK4A ,}

1999 • 46 citations

The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin

1998 • 36 citations

Activation of SOCS-3 Messenger Ribonucleic Acid in the Hypothalamus by Ciliary Neurotrophic Factor

1999 • 28 citations