Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats☆
Data up to Jan 2025
Total Citations Per Year
Abstract
References (84)
The Rat Brain in Stereotaxic Coordinates
1982 • 53,055 citations
The rat brain in stereotaxic coordinates
1983 • 28,962 citations
Handbook of Physiology.
1960 • 10,428 citations
Oxidative Stress, Caloric Restriction, and Aging
1996 • 3,136 citations
Handbook of the Biology of Aging
1990 • 1,219 citations
The Retardation of Aging in Mice by Dietary Restriction: Longevity, Cancer, Immunity and Lifetime Energy Intake
1986 • 968 citations
Measurement of local cerebral blood flow with iodo [14C] antipyrine
1978 • 927 citations
Cerebral Blood Flow and Metabolism
1994 • 779 citations
Dietary Restriction in Mice Beginning at 1 Year of Age: Effect on Life-Span and Spontaneous Cancer Incidence
1982 • 757 citations
Increased 3‐nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
1997 • 593 citations
Life Span Study of SPF Fischer 344 Male Rats Fed AdLibitum or Restricted Diets: Longevity, Growth, Lean Body Mass and Disease
1982 • 573 citations
Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain.
1996 • 493 citations
Medial temporal lesions in monkeys impair memory on a variety of tasks sensitive to human amnesia.
1985 • 366 citations
Dissociation of the Medial Prefrontal, Posterior Parietal, and Posterior Temporal Cortex for Spatial Navigation and Recognition Memory in the Rat
1994 • 364 citations
Oxidative Stress and Mitochondrial DNA Mutations in Human Aging
1998 • 355 citations
Medial temporal lesions in monkeys impair memory on a variety of tasks sensitive to human amnesia.
1985 • 353 citations
Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice
1994 • 346 citations
Human cerebral blood flow and oxygen consumption as related to aging
1956 • 332 citations
On the role of hippocampal connections in the performance of place and cue tasks: Comparisons with damage to hippocampus.
1984 • 322 citations
Minireview: Food Restriction in Rodents: An Evaluation of Its Role in the Study of Aging
1988 • 322 citations
Dopaminergic regulation of cerebral cortical microcirculation
1998 • 321 citations
Cerebral blood flow changes in benign aging and cerebrovascular disease
1984 • 316 citations
Effect of Age and Caloric Intake on Protein Oxidation in Different Brain Regions and on Behavioral Functions of the Mouse
1996 • 290 citations
Transient IGF-I gene expression during the maturation of functionally related central projection neurons
1991 • 287 citations
Decreases in Cerebral Microvasculature with Age Are Associated with the Decline in Growth Hormone and Insulin-Like Growth Factor 1*
1997 • 286 citations
Reduction in regional cerebral blood flow during normal aging in man.
1980 • 280 citations
Brain aging and Alzheimer's disease, “Wear and tear” versus “Use it or lose it”
1991 • 274 citations
Insulin-like growth factor-1 ameliorates age-related behavioral deficits
1998 • 271 citations
On the role of hippocampal connections in the performance of place and cue tasks: Comparisons with damage to hippocampus.
1984 • 270 citations
Handbook of the Biology of Aging
1991 • 259 citations
Astroglial and Vascular Interactions of Noradrenaline Terminals in the Rat Cerebral Cortex
1997 • 223 citations
Insulin-like growth factor I and its binding proteins in the cardiovascular system
1995 • 205 citations
Wear and tear
1871 • 163 citations
Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging
1995 • 155 citations
Fimbria–Fornix vs Selective Hippocampal Lesions in Rats: Effects on Locomotor Activity and Spatial Learning and Memory
1998 • 146 citations
Brain Dysfunction in Metabolic Disorders
1975 • 132 citations
Influence of the Restriction of Individual Dietary Components on Longevity And Age-Related Disease of Fischer Rats: The Fat Component and the Mineral Component
1988 • 132 citations
Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats
1999 • 124 citations
Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice.
1991 • 123 citations
Global cerebral ischemia activates nuclear factor-κB prior to evidence of DNA fragmentation
1997 • 121 citations
Regenerating endothelial cells express insulin-like growth factor-I immunoreactivity after arterial injury
1987 • 119 citations
Insulin‐like growth factor‐1 mRNA is increased in deafferented hippocampus: Spatiotemporal correspondence of a trophic event with axon sprouting
1995 • 114 citations
Regulation of insulin-like growth factor I messenger RNA levels in vascular smooth muscle cells.
1991 • 113 citations
Neuropsychological test performance, cognitive functioning, blood pressure, and age: The framingham heart study
1995 • 106 citations
Progressive failure of cerebral angiogenesis supporting neural plasticity in aging rats
1989 • 105 citations
BDNF and trkB mRNA expression in the hippocampal formation of aging rats
1993 • 102 citations
Local cerebral energy metabolism: its relationship to local functional activity and blood flow.
1980 • 96 citations
Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex
1987 • 93 citations
The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosis
1996 • 86 citations
The influence of dietary restriction on DNA repair in rodents: A preliminary study
1989 • 82 citations
Effects of Aging and Dietary Restriction on Tissue Protein Synthesis: Relationship to Plasma Insulin-like Growth Factor-1
1992 • 80 citations
Cerebral Vascular Smooth Muscle and Its Control
1978 • 79 citations
Interventions Based on the Possibility That Oxidative Stress Contributes to Sarcopenia
1995 • 79 citations
Insulin-like growth factor I and its binding proteins in the cardiovascular system
1995 • 77 citations
Decreases in Cerebral Microvasculature with Age Are Associated with the Decline in Growth Hormone and Insulin-Like Growth Factor 1
1997 • 74 citations
Ultrastructural analysis of tryptophan hydroxylase immunoreactive nerve terminals in the rat cerebral cortex and hippocampus: their associations with local blood vessels
1995 • 72 citations
DNA Damage and Repair in Human Tissues
1990 • 72 citations
Oxidative DNA damage levels in rats fed low-fat, high-fat, or calorie-restricted diets
1992 • 71 citations
Brain dysfunction in metabolic disorders
1974 • 69 citations
Influence of the Severity of Myocardial Ischemia on the Intensity of Ascorbyl Free Radical Release and on Postischemic Recovery during Reperfusion
1998 • 65 citations
The vascular response to nerve crush: relationship to Wallerian degeneration and regeneration
1993 • 64 citations
Cerebral Blood Flow and Metabolism
1993 • 63 citations
Transient expression of insulin-like growth factor I immunoreactivity by vascular cells during angiogenesis
1989 • 63 citations
Stable Xenon CT Cerebral Blood Flow Measurements Computed by a Single Compartment-Double Integration Model in Normal Aging and Dementia
1982 • 61 citations
Correlation of behavioral and cerebrovascular functions in the aging rat
1987 • 60 citations
Effect of Dietary Restriction on Liver Protein Synthesis in Rats
1985 • 58 citations
Age-Related Changes in Synaptic Neurochemistry
1990 • 54 citations
Moderate caloric restriction increases type 1 IGF receptors and protein synthesis in aging rats
1993 • 54 citations
Expression of nuclear redox factor ref-1 in the rat hippocampus following global ischemia induced by cardiac arrest
1997 • 49 citations
Frontal cortex grafts have opposite effects at different postoperative recovery times
1988 • 47 citations
Vasomotor responses of cerebral arterioles in situ to putative dopamine receptor agonists
1985 • 45 citations
Effect of age and dietary restriction on protein synthesis by isolated kidney cells
1985 • 44 citations
A morphometric study of blood vessel, neuron and glial cell distribution in young and old rat brain
1987 • 42 citations
Ontogeny of Pituitary Growth Hormone and Growth Hormone mRNA in the Chicken
1993 • 40 citations
Impact of aging on adenosine levels, A1/A2 responses, arrhythmogenesis, and energy metabolism in rat heart
1996 • 31 citations
Biological Effects of Dietary Restriction
1990 • 31 citations
Effects of increasing times of incomplete cerebral ischemia upon the energy state and lipid peroxidation in the rat
1997 • 28 citations
Aging in Rodents Fed Restricted Diets*,†
1985 • 27 citations
Modulation of Chemical Toxicity by Modification of Caloric Intake
1992 • 24 citations
Some biological aspects of the aging brain
1980 • 18 citations
Prevention of Free Radical Damage by Food Restriction
1991 • 17 citations
Effect of Aging on A1-Adenosine Receptor-Mediated Inhibition of Norepinephrine Release in the Rat Heart
1998 • 13 citations
Effects of Caloric Restriction on the Maintenance of Genetic Fidelity
1990 • 6 citations
Insulin-like Growth Factor-1 Regulates Activity of Dopamine D2 Receptors in Aged Animals
1998 • 3 citations