Some biological aspects of the aging brain

Synaptic density in human frontal cortex — Developmental changes and effects of aging

1979 • 2,587 citations

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

1978 • 2,036 citations

Human Memory and the Cholinergic System

1974 • 1,378 citations

NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

1976 • 1,272 citations

Changes in brain weights during the span of human life: Relation of brain weights to body heights and body weights

1978 • 982 citations

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

1963 • 956 citations

Brain Aluminum Distribution in Alzheimer's Disease and Experimental Neurofibrillary Degeneration

1973 • 843 citations

The aftermath of boxing

1973 • 812 citations

Alzheimer's Disease: Senile Dementia and Related Disorders

1979 • 801 citations

ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

1964 • 646 citations

Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex

1955 • 624 citations

NEOCORTICAL CHOLINERGIC NEURONS IN ELDERLY PEOPLE

1977 • 490 citations

Alzheimer's Neurofibrillary Changes

1962 • 396 citations

Brain Acetylcholine: Control by Dietary Choline

1976 • 386 citations

EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS

1968 • 379 citations

Biology of cholinergic function

1977 • 368 citations

Neurofibrillary tangles of paired helical filaments

1976 • 366 citations

The development of the pathologic changes of Alzheimer's disease and senile dementia in patients with Down's syndrome.

1973 • 340 citations

EXPERIMENTAL PRODUCTION OF NEUROFIBRILLARY DEGENERATION

1965 • 332 citations

Regional distribution of muscarinic acetylcholine receptor in normal and Alzheimer's-type dementia brains

1977 • 313 citations

The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies and "rod-like" structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex.

1968 • 298 citations

Correlation between Scores for Dementia and Counts of ‘Senile Plaques’ in Cerebral Grey Matter of Elderly Subjects

1966 • 293 citations

Neuritic (Senile) Plaques and Filamentous Changes in Aged Rhesus Monkeys

1973 • 270 citations

THE FINE STRUCTURE OF SOME INTRAGANGLIONIC ALTERATIONS

1968 • 239 citations

THE DENSITY OF SYNAPSES AND NEURONS IN NORMAL, MENTALLY DEFECTIVE AND AGEING HUMAN BRAINS

1975 • 223 citations

Patterns of Astroglial Hypertrophy and Neuronal Degeneration in the Hippocampus of Aged, Memory-deficient Rats

1977 • 219 citations

NEUROFIBRILLARY PATHOLOGY

1970 • 214 citations

Senile plaques and cerebral amyloidosis in aged dogs. A histochemical and ultrastructural study.

1970 • 205 citations

Structural changes in the aging brain

1975 • 170 citations

Fine structural localization of acid phosphatase in senile plaques in Alzheimer's presenile dementia

1967 • 163 citations

Pattern and field in cortical structure: The rabbit

1967 • 162 citations

Immuno-electron microscopic localization of immunoglobulins in amyloid fibrils of senile plaques

1976 • 142 citations

Physiology and Pathology of Dendrites

1975 • 135 citations

VOLUME OF THE VENTRAL COCHLEAR NUCLEUS IN MAN

1972 • 129 citations

Quantitative study on dendrites and dendritic spines in Alzheimer's disease and senile dementia.

1975 • 129 citations

ENZYME HISTOCHEMICAL STUDIES OF SENILE PLAQUES

1965 • 127 citations

EVIDENCE THAT ALZHEIMER NEUROFIBRILLARY TANGLES ORIGINATE FROM NEUROTUBULES

1979 • 125 citations

Decrease in the number of synapses in the senescent brain: A quantitative electron microscopic analysis of the dentate gyrus molecular layer in the rat

1976 • 119 citations

Infectious Etiology of Neuritic (Senile) Plaques in Mice

1975 • 113 citations

Biochemical and immunological characterization of neurofilaments in experimental neurofibrillary degeneration induced by aluminum

1979 • 112 citations

Nerve Cell Loss with Aging in the Putamen

1978 • 101 citations

CHEMICAL STUDIES ON ALZHEIMERʼS DISEASE

1965 • 96 citations

The effects of age upon the main nucleus of the inferior olive in the human

1974 • 95 citations

THE QUANTITATIVE ASSESSMENT OF LIPOFUSCIN PIGMENT, CYTOPLASMIC RNA AND NUCLEOLAR VOLUME IN SENILE DEMENTIA

1978 • 88 citations

Paired helical filaments of the Alzheimer type in cultured neurones

1978 • 73 citations

Microchemical pathology of the cerebral cortex in pre-senile dementias.

1964 • 72 citations

Age Changes in the Neuronal Microenvironment

1972 • 67 citations

Structural alterations in neurons of aged canine neocortex: A Golgi study

1978 • 66 citations

Alzheimer neurofibrillary change in subacute sclerosing panencephalitis

1977 • 65 citations

Clinical, morphologic, and neurochemical aspects in the aging central nervous system

1975 • 47 citations

Follow-up 15 Years After a Geronto-psychiatric Prevalence Study Conditions Concerning Death, Cause of Death, and Life Expectancy in Relation to Psychiatric Diagnosis

1977 • 45 citations

Histochemical similarity of senile plaque amyloid to apudamyloid

1977 • 31 citations

ACID PHOSPHATASE IN THE SENILE BRAIN

1949 • 27 citations

Spinal fluid aluminum levels in patients with alzheimer disease

1979 • 20 citations

Some American Poets: A Personal Record

1977 • 2 citations