ADP-ribosyl transferase, rearrangement of DNA, and cell differentiation

CHROMOSOME ORGANIZATION AND GENIC EXPRESSION

1951 • 1,174 citations

(ADP-ribose)n participates in DNA excision repair

1980 • 1,112 citations

Controlling Elements and the Gene

1956 • 837 citations

5-Methylcytosine in Eukaryotic DNA

1981 • 744 citations

The origin of human cancers

1981 • 653 citations

Poly ADP-ribose and ADP-ribosylation of proteins

1976 • 572 citations

Active chromatin

1982 • 549 citations

Novel inhibitors of poly(ADP-ribose) synthetase

1980 • 519 citations

Adult frogs derived from the nuclei of single somatic cells

1962 • 441 citations

Regulation of DNA ligase activity by poly(ADP-ribose)

1982 • 369 citations

Molecular basis for trypanosome antigenic variation

1982 • 369 citations

DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation

1982 • 351 citations

Poly(ADP-ribose) levels in carcinogen-treated cells

1979 • 346 citations

Poly(ADP-ribose) and ADP-ribosylation of proteins

1976 • 283 citations

The Involvement of Poly(ADP‐ribose) Polymerase in the Degradation of NAD Caused by γ‐Radiation and N‐Methyl‐N‐Nitrosourea

1979 • 275 citations

Transposable genetic elements as agents of gene instability and chromosomal rearrangements

1977 • 271 citations

Conformational constraints in nuclear dna

1976 • 257 citations

Role of DNA breaks and ADP-ribosyl transferase activity in eukaryotic differentiation demonstrated in human lymphocytes

1982 • 238 citations

Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element

1982 • 232 citations

Selective Silencing of Eukaryotic DNA

1975 • 224 citations

Genome instability in a region of human DNA enriched in Alu repeat sequences

1982 • 220 citations

ADP-ribosylation of nuclear proteins

1980 • 219 citations

Regulation of transcription in expressed and unexpressed mating type cassettes of yeast

1981 • 210 citations

The Enhancement of Cytotoxicity of N‐Methyl‐N‐nitrosourea and of y‐Radiation by Inhibitors of Poly(ADP‐ribose) Polymerase

1980 • 196 citations

Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled DNA synthesis in normal human lymphocytes

1982 • 181 citations

Breakage of DNA and alterations in folded genomes by inducers of differentiation in Friend erythroleukemic cells.

1978 • 173 citations

The role of gene deletion in the immunoglobulin heavy chain switch

1980 • 164 citations

Interrelationship between poly (ADP-Rib) synthesis, intracellular NAD levels, and muscle or cartilage differentiation from mesodermal cells of embryonic chick limb.

1975 • 158 citations

Building for Earthquakes

2004 • 157 citations

Poly(adenosine diphosphate ribose)

1982 • 154 citations

Poly(ADP-ribosylation) of a DNA topoisomerase.

1983 • 145 citations

Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes

1982 • 144 citations

Characterization and comparison of poly(adenosine diphosphoribose) synthesis and DNA synthesis in nucleotide-permeable cells

1978 • 142 citations

Specific inhibition of poly adpribose polymerase by thymidine and nicotinamide in HeLa cells

1971 • 139 citations

Poly(ADP‐ribose) polymerase activity in nucleotide permeable cells

1978 • 125 citations

TRANSPOSABLE ELEMENTS IN DROSOPHILA AND OTHER DIPTERA

1980 • 125 citations

Inhibition of nuclear NAD nucleosidase and poly ADP-ribose polymerase activity from rat liver by nicotinamide and 5′-methyl nicotinamide

1971 • 122 citations

Stimulation of nuclear poly(adenosine diphosphate-ribose) polymerase activity from HeLa cells by endonucleases

1975 • 117 citations

Expression of poly(adenosine diphosphate-ribose) polymerase activity in erythroleukemic mouse cells during cell cycle and erythropoietic differentiation.

1978 • 117 citations

Magnitude and significance of NAD turnover in human cell line D98/AH2

1976 • 105 citations

Genetic Content of Adult Somatic Cells tested by Nuclear Transplantation from Cultured Cells

1970 • 97 citations

Stimulation of poly(ADP-ribose) polymerase activity by the anti-tumour antibiotic, streptozotocin

1975 • 94 citations

The Effect of Inhibition of (ADP‐ribose)_n Biosynthesis on DNA Repair Assayed by the Nucleoid Technique

1981 • 91 citations

Chromosomal rearrangement and carcinogenesis

1982 • 83 citations

Non-immunoglobulin-associated DNA rearrangements in mouse plasmacytomas.

1982 • 82 citations

Poly(adenosine diphosphate ribose) polymerase activity and nicotinamide adenine dinucleotide in differentiating cardiac muscle

1976 • 80 citations

DNA Repair

1981 • 78 citations

Inhibition of (ADP-ribose)n biosynthesis retards DNA repair but does not inhibit DNA repair synthesis

1981 • 71 citations

Radioresistance of Phytohemagglutinin-Treated Normal and Leukemic Lymphocytes<xref ref-type="fn" rid="FN2">2</xref>

1964 • 71 citations

ADP-Ribose in DNA Repair

1982 • 70 citations

Inhibition of poly(ADP‐ribose) polymerase by methylated xanthines and cytokinins

1978 • 68 citations

Thyroid membrane ADP ribosyltransferase activity. Stimulation by thyrotropin and activity in functioning and nonfunctioning rat thyroid cells in culture.

1981 • 66 citations

On the mechanism of preadipocyte differentiation. Masking of poly(ADP-ribose) synthetase activity during differentiation of 3T3-L1 preadipocytes.

1981 • 59 citations

Inhibitors of poly(ADP-ribose) polymerase enhance unscheduled DNA synthesis in human peripheral lymphocytes

1981 • 58 citations

Involvement of poly(ADP-ribose) metabolism in induction of differentiation of HL-60 promyelocytic leukemia cells

1982 • 50 citations

Effect of nicotinamide on RNA and DNA synthesis and on poly(ADP‐ribose) polymerase activity in normal and phytohemagglutinin stimulated human lymphocytes

1980 • 46 citations

REVIEW

1981 • 40 citations

Abnormal NAD+ levels in cells from patients with Fanconi's anaemia

1982 • 39 citations

Effect of Azaserine on the Biosynthesis of Diphosphopyridine Nucleotide in Mouse

1961 • 39 citations

Cancer: Step by step into carcinogenesis

1983 • 37 citations

Genetic instability in Drosophila melanogaster

1974 • 32 citations

The activity and properties of poly(adenosine diphosphate ribose) polymerase in vitro during the embryonic development of the South African clawed toad Xenopus laevis

1979 • 31 citations

DNA gyrase stimulates transcription.

1980 • 29 citations

19 DNA Gyrase and Other Type II Topoisomerases

1981 • 28 citations

Mono(ADP-ribosyl)ation and Poly(ADP-ribosyl)ation of Proteins in Developing Liver and in Hepatomas. Relation of Conjugate Subfractions to Metabolic Competence and Proliferation Rates

1981 • 27 citations

Enhanced chondrocytic differentiation in chick limb bud cell cultures by inhibitors of poly(ADP-ribose) synthetase

1983 • 26 citations

Evidence for translocation of DNA sequences during sea urchin embryogenesis.

1978 • 23 citations

Nicotinamide adenine dinuleotides in acute liver injury: Effects of azaserine and puromycin in the rat

1966 • 19 citations

Isoproterenol-induced ADP-ribosylation of a single plasma membrane protein of cultured differentiated RL-PR-C hepatocytes

1981 • 19 citations

Protein-bound mono(ADP-ribose) residues in differentiating cells of Dictyostelium discoideum

1980 • 16 citations

Expression of immunoglobulin genes.

1982 • 15 citations

Mono ADP-ribosylation and poly ADP-ribosylation of proteins in normal and malignant tissues

1982 • 15 citations

Effect of 3-acetylpyridine on tissue differentiation of the embryonic chick limb

1976 • 14 citations

Immunoglobulin switch region-like sequences inDrosophila melanogaster

1982 • 14 citations

Unilateral internuclear gene transfer and cell differentiation in Schizophyllum

1981 • 13 citations

Adenosine incorporation by unfertilized mouse ova: adenylation of RNA and adenosine diphosphate ribosylation of protein

1978 • 10 citations

NAD turnover during early development of Xenopus laevis

1983 • 10 citations

Direct radioactive labelling of poly(ADP-ribose) in developing Xenopus laevis embryos

1983 • 8 citations

Therapeutic promise maintained

1982 • 8 citations

5-Bromodeoxyuridine Inhibits Sequence Changes Within Inverted Repeat DNA During Embryogenesis

1979 • 6 citations

Antimalarial activity of inhibitors of ADP-ribosyl transferase against Plasmodium yoelii infection in mice. 1. Preliminary data.

1982 • 6 citations

Subfractions and Subcellular Distribution of Mono(ADP-ribosyl) Proteins in Eukaryotic Cells

1982 • 5 citations