Poly(adenosine diphosphate ribose)
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Abstract
References (161)
Chromatin Structure: A Repeating Unit of Histones and DNA
1974 • 2,514 citations
Spheroid Chromatin Units (ν Bodies)
1974 • 1,366 citations
(ADP-ribose)n participates in DNA excision repair
1980 • 1,112 citations
Chromatin Structure: Oligomers of the Histones
1974 • 910 citations
Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system
1978 • 902 citations
Electron microscopic and biochemical evidence that chromatin structure is a repeating unit
1975 • 860 citations
Subunit structure of chromatin
1974 • 764 citations
ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.
1978 • 732 citations
The effect of sodium butyrate on histone modification
1978 • 680 citations
NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,.
1975 • 619 citations
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone
1979 • 517 citations
Poly(ADP-ribose) synthesis in vitro programmed by damaged DNA. A comparison of DNA molecules containing different types of strand breaks.
1980 • 488 citations
Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.
1977 • 436 citations
Processing of Newly Synthesized Histone Molecules
1975 • 434 citations
Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor.
1977 • 391 citations
ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA.
1980 • 378 citations
Poly(ADP-ribose) levels in carcinogen-treated cells
1979 • 346 citations
ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products.
1980 • 323 citations
Studies on the Polymer of Adenosine Diphosphate Ribose
1967 • 306 citations
Poly(ADP-ribose) and ADP-ribosylation of proteins
1976 • 283 citations
The Involvement of Poly(ADP‐ribose) Polymerase in the Degradation of NAD Caused by γ‐Radiation and N‐Methyl‐N‐Nitrosourea
1979 • 275 citations
Comparison of Nucleolar Proteins of Normal Rat Liver and Novikoff Hepatoma Ascites Cells by Two-Dimensional Polyacrylamide Gel Electrophoresis
1973 • 260 citations
Biochemical evidence of variability in the DNA repeat length in the chromatin of higher eukaryotes.
1976 • 240 citations
Association of Poly(Adenosine Diphosphoribose) Synthesis with DNA Damage and Repair in Normal Human Lymphocytes
1979 • 222 citations
ADP-ribosylation of nuclear proteins
1980 • 219 citations
A model for particulate structure in chromatin
1974 • 214 citations
ADP-ribosylation of histone H1. Identification of glutamic acid residues 2, 14, and the COOH-terminal lysine residue as modification sites.
1980 • 213 citations
Variation in chromatin structure in two cell types from the same tissue: a short DNA repeat length in cerebral cortex neurons
1977 • 209 citations
Purification and Properties of a Glycohydrolase from Calf Thymus Splitting Ribose-Ribose Linkages of Poly(Adenosine Diphosphate Ribose)
1974 • 205 citations
The Enhancement of Cytotoxicity of N‐Methyl‐N‐nitrosourea and of y‐Radiation by Inhibitors of Poly(ADP‐ribose) Polymerase
1980 • 196 citations
Molecular basis of control of mitotic cell division in eukaryotes
1974 • 195 citations
ADP ribosylation of rat liver nucleosomal core histones.
1979 • 194 citations
Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.
1977 • 193 citations
Modification of Histones during Spermiogenesis in Trout: A Molecular Mechanism for Altering Histone Binding to DNA
1970 • 187 citations
ADP-ribosylation of histone H2B. Identification of glutamic acid residue 2 as the modification site.
1980 • 185 citations
Enzymic Adenosine Diphosphate Ribosylation of Histone and Poly Adenosine Diphosphate Ribose Synthesis in Rat Liver Nuclei
1968 • 184 citations
Isolation of an avian erythrocyte protein possessing ADP-ribosyltransferase activity and capable of activating adenylate cyclase
1978 • 175 citations
Involvement of nicotinamide adenine dinucleotide in the action of cholera toxin in vitro.
1975 • 171 citations
ADP ribosylation of rat liver lysine-rich histone in vitro.
1979 • 166 citations
The DNA repeat lengths in chromatins from sea urchin sperm and gastrula cells are markedly different
1976 • 165 citations
Adenosine Diphosphate Ribosylation of Aminoacyl Transferase II and Inhibition of Protein Synthesis by Diphtheria Toxin
1971 • 161 citations
The Methylation of Histones during Regeneration of the Liver
1968 • 160 citations
Interrelationship between poly (ADP-Rib) synthesis, intracellular NAD levels, and muscle or cartilage differentiation from mesodermal cells of embryonic chick limb.
1975 • 158 citations
Structure of poly(adenosine diphosphate ribose): identification of 2'-[1''-ribosyl-2''-(or 3''-)(1'''-ribosyl)]adenosine-5',5'',5'''-tris(phosphate) as a branch linkage.
1979 • 149 citations
Splitting of the Ribose-Ribose Linkage of Poly(Adenosine Diphosphate-Ribose) by a Calf Thymus Extract
1971 • 148 citations
Characterization and comparison of poly(adenosine diphosphoribose) synthesis and DNA synthesis in nucleotide-permeable cells
1978 • 142 citations
Polymerization of the adenosine 5′-diphosphate-ribose moiety of nicotinamide-adenine dinucleotide by nuclear enzyme. I. Enzymatic reactions
1967 • 140 citations
Bovine thymus poly(adenosine diphosphate ribose) polymerase. Physical properties and binding to DNA.
1980 • 138 citations
Natural occurrence of poly(ADP-ribosyl) histones in rat liver.
1975 • 127 citations
Poly(ADP‐ribose) polymerase activity in nucleotide permeable cells
1978 • 125 citations
Evidence for the involvement of H1 histone phosphorylation in chromosome condensation
1980 • 123 citations
Properties of the Complex between Histone H1 and Poly(ADP‐ribose) Synthesised in HeLa Cell Nuclei
1977 • 119 citations
Stimulation of nuclear poly(adenosine diphosphate-ribose) polymerase activity from HeLa cells by endonucleases
1975 • 117 citations
Expression of poly(adenosine diphosphate-ribose) polymerase activity in erythroleukemic mouse cells during cell cycle and erythropoietic differentiation.
1978 • 117 citations
Purification and characterization of poly(ADP-ribose) synthetase from calf thymus.
1979 • 113 citations
Purification and properties of poly(adenosine diphosphate ribose) synthetase.
1977 • 112 citations
Bovine thymus poly(adenosine diphosphate ribose) polymerase.
1978 • 112 citations
Elongation Factor 2
1974 • 108 citations
Changes in nucleolar proteins and their phosphorylation patterns during liver regeneration.
1975 • 107 citations
Studies on the Polymer of Adenosine Diphosphate Ribose
1967 • 103 citations
Purification of ADP-ribosylated nuclear proteins by covalent chromatography on dihydroxyboryl polyacrylamide beads and their characterization.
1978 • 96 citations
Altered guanine nucleotide hydrolysis as basis for increased adenylate cyclase activity after cholera toxin treatment.
1977 • 92 citations
DNA synthesis in permeabilized mouse L cells
1976 • 91 citations
Induction of erythroid differentiation of murine erythroleukemia cells by nicotinamide and related compounds.
1979 • 90 citations
Adenosine Diphosphoribosylation of Certain Basic Chromosomal Proteins in Isolated Trout Testis Nuclei
1977 • 87 citations
Naturally-occurring antibodies to poly(ADP-ribose) in patients with systemic lupus erythematosus
1977 • 86 citations
Properties of Purified Calf Thymus Poly(Adenosine Diphosphate Ribose) Polymerase. Comparison of the DNA-Independent and the DNA-Dependent Enzyme
1979 • 86 citations
Synthesis of DNA and Poly(Adenosine Diphosphate Ribose) in Normal and Chronic Lymphocytic Leukemia Lymphocytes
1978 • 84 citations
Purification and properties of calf thymus polyadenosine diphosphate ribose polymerase.
1976 • 81 citations
Substrate specificity and partial purification of a stereospecific NAD- and guanidine-dependent ADP-ribosyltransferase from avian erythrocytes.
1979 • 79 citations
Purification and Properties of Poly(ADP‐ribose) Polymerase from Pig‐Thymus Nuclei
1978 • 77 citations
Two Different Types of Bonds Linking Single ADP‐Ribose Residues Covalently to Proteins
1978 • 75 citations
NAD-dependent ADP-ribosylation of arginine and proteins by Escherichia coli heat-labile enterotoxin.
1979 • 73 citations
Primary structure at the site in beef and wheat elongation factor 2 of ADP‐ribosylation by diphtheria toxin
1979 • 73 citations
Novel enzyme from rat liver that cleaves an ADP-ribosyl histone linkage.
1978 • 71 citations
Initiation of poly(ADP-ribosyl) histone synthesis by poly(ADP-ribose) synthetase.
1980 • 71 citations
ADP-Ribosylated Histone H1 from HeLa Cultures. Fundamental Differences to (ADP-Ribose)n-Histone H1 Conjugates Formed in vitro
1978 • 70 citations
The polymerization of adenosine 5'-diphosphate-ribose moiety of NAD by nuclear enzyme. II. Properties of the reaction product.
1967 • 68 citations
Inhibition of poly(ADP‐ribose) polymerase by methylated xanthines and cytokinins
1978 • 68 citations
Association of poly(ADP-rib) synthesis with cessation of DNA synthesis and DNA fragmentation
1979 • 66 citations
Poly(ADP-ribosy)ation of nuclear proteins. Enzymatic elongation of chemically synthesized ADP-ribose-histone adducts.
1979 • 64 citations
Modulation of Protein Function
1979 • 62 citations
Release of template restriction for DNA synthesis by poly ADP(ribose) polymerase during the HeLa cell cycle
1975 • 60 citations
The polymerization of adenosine 5′-diphosphate-ribose moiety of NAD by nuclear enzyme
1967 • 59 citations
Nitrosourea interaction with chromatin and effect on poly(adenosine diphosphate ribose) polymerase activity.
1979 • 58 citations
Isolation and properties of the trypsin-derived ADP-ribosyl peptide from diphtheria toxin-modified yeast elongation factor 2.
1978 • 58 citations
Purification and properties of calf thymus polyadenosine diphosphate ribose polymerase
1977 • 57 citations
NAD glycohydrolase and ADP-ribosyltransferase activities are intrinsic to the A1 peptide of choleragen.
1979 • 57 citations
Poly(ADP-ribose) synthesis, a marker of granulocyte differentiation.
1980 • 56 citations
The in vivo distribution of immunoreactive larger than tetrameric polyadenosine diphosphoribose in histone and non-histone protein fractions of rat liver.
1979 • 52 citations
Bovine thymus poly(ADP-ribose) polymerase histone-dependent and Mg2+-dependent reaction.
1979 • 50 citations
A13C NMR study of poly(adenosine diphosphate ribose) and its monomers: evidence of α-(1″→2′) ribofuranosyl ribofuranoside residue
1977 • 50 citations
The dynamic state of liver nucleolar proteins as reflected by their changes during administration of thioacetamide
1974 • 50 citations
Poly(adenosine diphosphate ribose) synthesis during the cell cycle of transformed hamster lung cells.
1973 • 49 citations
Synthesis of poly(adenosine diphosphate ribose) in synchronized Chinese hamster cells
1978 • 49 citations
ADP‐Ribosylation of Nuclear Proteins in Normal Lymphocytes and in Low‐Grade Malignant Non‐Hodgkin Lymphoma Cells
1980 • 49 citations
Nucleosome periodicity in HeLa cell chromatin as probed by micrococcal nuclease.
1979 • 47 citations
Effect of nicotinamide on RNA and DNA synthesis and on poly(ADP‐ribose) polymerase activity in normal and phytohemagglutinin stimulated human lymphocytes
1980 • 46 citations
Evidence for the close proximity of histones H1 and H3 in chromatin of intact nuclei
1978 • 45 citations
ADP-ribosylation of isolated nuclei from HeLa cells, rat liver, fetal rat liver, and Novikoff hepatoma. Effect of nicotinamide adenine dinucleotide analogs on template activity for DNA synthesis, incorporation into nuclear proteins, and a new 1''-3' osidic linkage.
1977 • 45 citations
Relation of poly(adenosine diphosphoribose) synthesis to DNA synthesis and cell growth
1978 • 44 citations
The significance of antibodies to poly(adenosine diphosphate-ribose) in systemic lupus erythematosus.
1979 • 44 citations
A nuclear protein-modifying enzyme is responsive to ordered chromatin structure
1978 • 43 citations
Poly(Adenosine Diphosphate Ribose) Polymerase and Deoxyribonucleic Acid Damage
1977 • 42 citations
Demonstration of high molecular weight poly (adenosine diphosphate ribose)
1978 • 41 citations
Poly (ADP‐ribose) Polymerase from Ehrlich Ascites Tumor Cells
1978 • 40 citations
Purification and Properties of the NAD+: Protein ADP‐ribosyltransferase Responsible for the T4‐Phage‐Induced Modification of the œ Subunit of DNA‐Dependent RNA Polymerase of Escherichia coli
1977 • 40 citations
Changes in the level of poly ADP-ribosylation during a cell cycle
1978 • 40 citations
Poly(ADPribose) levels as a function of chick limb mesenchymal cell development as studied in vitro and in vivo
1979 • 38 citations
Charge-transfer and water-mediated chromatography
1979 • 38 citations
Semiconservative DNA replication in vitro I. Properties of two systems derived from mouse P-815 cells by permeabilization or lysis with Brij-58
1977 • 38 citations
Effect of polyamines and divalent cations on histone H1-poly(adenosine diphosphate ribose) complex formation
1978 • 38 citations
A new highly sensitive and selective chemical assay for poly(ADP-ribose)
1980 • 37 citations
The Periodic Synthesis of S-Adenosylmethionine:Protein Methyltransferases during the HeLa S-3 Cell Cycle
1973 • 36 citations
The distribution of histone H1 subfractions in chromatin subunits
1979 • 36 citations
Production of Antibodies against ADP‐ribose and 5′‐AMP with the Aid of N6‐Carboxymethylated ADP‐ribose Conjugates
1978 • 36 citations
Adenosine diphosphate ribosylation of histone H1 by purified calf thymus polyadenosine diphosphate ribose polymerase
1980 • 35 citations
Analysis of larger than tetrameric poly(adenosine diphosphoribose) by a radioimmunoassay in nuclei separated in organic solvents
1978 • 35 citations
Studies of nuclear ADP-ribosylation
1980 • 35 citations
Effect of 1-methyl-1-nitrosourea on poly(adenosine diphosphate-ribose) polymerase activity at the nucleosomal level.
1979 • 32 citations
Natural occurence of a biopolymer, poly (adenosine diphosphate ribose)
1977 • 32 citations
The activity and properties of poly(adenosine diphosphate ribose) polymerase in vitro during the embryonic development of the South African clawed toad Xenopus laevis
1979 • 31 citations
Determination of ADP‐ribose and Poly(ADP‐ribose) by a New Radioimmunoassay
1978 • 30 citations
Effect of Poly(ADP-ribose) Formation on DNA Synthesis in Chick-Embryo-Liver Nuclei. Possible Mechanism of Template Activation
1978 • 28 citations
Control of histone H1 dimer-poly(ADP-ribose) complex formation by poly(ADP-ribose) glycohydrolase
1977 • 28 citations
Demonstration of in vitro covalent modification of chromosomal proteins by poly(adp) ribosylation in plant nuclei
1979 • 27 citations
Covalent Structural Modification of DNA-Dependent RNA Polymerase as a Means for Transcriptional Control
1977 • 27 citations
The Modification of Nuclear Proteins by ADP‐ribosylation
1977 • 26 citations
High molecular weight DNA intermediates synthesized by permeabilized L cells
1977 • 26 citations
The effect of p, d, and f Gaussian polarization functions on the computed one-electron properties of AHn oxygen and sulfur hydrides
1978 • 25 citations
Properties of poly(ADP-ribose) synthetase from rat pancreas and poly(ADP-ribosylation) of basic nuclear proteins
1978 • 25 citations
Comparative studies on antibody and antibody production to poly(ADP-ribose) in mice.
1978 • 24 citations
Histone inhibition of DNA synthesis in eukaryotic cells permeable to macromolecules
1976 • 24 citations
Induction of specific antibodies to poly(ADP–ribose) in rabbits by double-stranded RNA, poly(A)·poly(U)
1978 • 24 citations
Poly(ADP‐ribose) metabolizing enzymes in nuclei and nucleoli of Tetrahymena Pyriformis
1978 • 22 citations
Identification of a protease inhibitor from rat peritoneal macrophages as poly(ADP-ribose).
1980 • 22 citations
Formation and characterization of antibody against 2′-(5″-phosphoribosyl)-5′ AMP, the monomer form of poly (adenosine diphosphate ribose)
1978 • 21 citations
Non‐preferential localization of poly(ADP‐ribose) polymerase activity in transcriptionally active chromatin
1978 • 19 citations
Effect of polyamines on ADP-ribosylation by chick-embryo-liver nuclei
1980 • 19 citations
Determination by Radioimmunoassay of the Sum of Oxidized and Reduced Forms of NAD and NADP in Picomole Quantities from the Same Acid Extract
1979 • 18 citations
Probes to study the effect of methyl nitrosourea on ADP-ribosylation and chromatin structure at the subunit level
1980 • 17 citations
A new technique for the isolation and fluorometric determination of polyadenosine diphosphate ribose in vivo
1978 • 17 citations
ADP-ribosylation of nuclear proteins
1979 • 16 citations
Protein-bound mono(ADP-ribose) residues in differentiating cells of Dictyostelium discoideum
1980 • 16 citations
Effect of DNA on poly (ADP-ribose) glycohydrolase and the degradation of histone H1-poly (ADP ribose) complex from HeLa cell nuclei
1978 • 16 citations
Kinetics of activation of ADP‐ribosylation and adenylate cyclase by cholera toxin in cloned differentiated hepatocytes
1978 • 16 citations
Spermine-induced variations in the adenosine 5'-diphosphate ribosylation patterns of nuclear proteins from rat liver and hepatoma.
1979 • 15 citations
In vitro ADP‐ribosylation of histones by purified calf thymus polyadenosine diphosphate ribose polymerase
1980 • 15 citations
A Chromatin-Bound Neutral Protease and Its Inhibitor in Rat Peritoneal Macrophages1
1978 • 12 citations
EMBO Workshop and 14. Konferenz der Gesellschaft für Biologische Chemie. Structure and Function of Poly(ADP-Ribose)
1972 • 12 citations
V and C parts of immunoglobulin κ-chain genes are separate in myeloma
1978 • 12 citations
Poly(Adenosine Diphosphate Ribose) Polymerase Purification in an Aqueous/Organic-Solvent System
1977 • 8 citations
Poly(Adenosine Diphosphate Ribose) Synthesis during Herpes Simplex Virus Infection
1979 • 8 citations
The Activity of Poly(Adenosine Diphosphate Ribose) Polymerase during the Embryonic Development of the South African Clawed Toad Xenopus laevis
1977 • 8 citations
Effect of heparin or removal of lysine-rich histone fraction on the poly(ADP-ribose) polymerase, DNA polymerase and template activity of isolated swine aortic nuclei
1978 • 8 citations
Seminar on Poly(ADP-Ribose) and ADP-ribosylation of Protine
1975 • 8 citations
Charge‐transfer chromatography
1978 • 7 citations
Seminar on Poly(ADP-Ribose) and ADP-ribosylation of Protine
1975 • 6 citations
An inhibitor of poly(adenosine diphosphate ribose) glycohydrolase found in vivo in germinating wheat embryos
1980 • 5 citations
Characterization of poly(adenosine diphosphate ribosylated) protein isolated from mouse L1210 cells in vivo
1980 • 2 citations
Seminar on Poly(ADP-Ribose) and ADP-ribosylation of Protine
1975 • 2 citations