Transposable genetic elements as agents of gene instability and chromosomal rearrangements

Evolution by Gene Duplication

1970 • 6,000 citations

Evolution by gene duplication

1970 • 5,849 citations

The origin and behavior of mutable loci in maize

1950 • 1,592 citations

CHROMOSOME ORGANIZATION AND GENIC EXPRESSION

1951 • 1,174 citations

Controlling Elements and the Gene

1956 • 837 citations

Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

1976 • 726 citations

Episomes

1962 • 602 citations

The Bacteriophage Lambda.

1971 • 573 citations

DNA: Insertion Elements, Plasmids, and Episomes.

1977 • 530 citations

CONTROLLING ELEMENTS IN MAIZE

1974 • 408 citations

Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition

1975 • 318 citations

Transposable genetic elements and plasmid evolution

1976 • 315 citations

Molecular Biology of Bacteriophage Mu

1975 • 239 citations

INDUCTION OF INSTABILITY AT SELECTED LOCI IN MAIZE

1953 • 238 citations

IS1 is involved in deletion formation in the gal region of E. coli K12

1975 • 229 citations

IS2, a genetic element for turn-off and turn-on of gene activity in E. coli

1974 • 182 citations

BACTERIOPHAGE MU AS A TRANSPOSITION ELEMENT

1976 • 174 citations

Site specific recA--independent recombination between bacterial plasmids: involvement of palindromes at the recombinational loci.

1975 • 173 citations

Some Parallels Between Gene Control Systems in Maize and in Bacteria

1961 • 163 citations

Gene duplication in experimental enzyme evolution

1974 • 151 citations

Electron microscopy of polar insertions in the lac operon of Escherichia coli

1972 • 148 citations

Effect of Rho on Transcription of Bacterial Operons

1973 • 146 citations

THE GALACTOSE OPERON OF E. COLI K-12. II. A DELETION ANALYSIS OF OPERON STRUCTURE AND POLARITY

1969 • 146 citations

Multiple copies of the insertion-DNA sequences IS1 and IS2 in the chromosome of E. coli K-12

1973 • 135 citations

THE GALACTOSE OPERON OF E. COLI K-12. I. STRUCTURAL AND PLEIOTROPIC MUTATIONS OF THE OPERON

1969 • 132 citations

Genetics and chemistry of bacterial flagella

1969 • 131 citations

Insertion mutations in microorganisms

1972 • 113 citations

THE GENETICS OF A MUTABLE GENE AT THE WHITE LOCUS OF DROSOPHILA MELANOGASTER

1967 • 97 citations

Mutations of coliphage λ affecting the expression of replicative functions O and P

1970 • 86 citations

Strong-polar mutations in the transferase gene of the galactose operon in E. coli

1967 • 82 citations

O o mutations in the galactose operon in E. coli

1967 • 71 citations

The En mutable system in maize

1970 • 67 citations

PHASE VARIATION OF REGULATORY ELEMENTS IN MAIZE

1966 • 60 citations

Isolation of polar insertion mutants and the direction of transcription of ribosomal protein genes in E. coli

1975 • 55 citations

Controlling elements and mutable loci in maize: Their relationship to bacterial episomes

1970 • 54 citations

MUTABLE a1 OF THE En SYSTEM IN MAIZE

1961 • 54 citations

CONTROL OF GENE EXPRESSION

1969 • 52 citations

STABILITY OF THE SUPPRESSOR ELEMENT IN TWO MUTATOR SYSTEMS AT THE A 1 LOCUS IN MAIZE

1966 • 51 citations

Genetic instability in Drosophila melanogaster

1974 • 41 citations

Studies of dotted, a regulatory element in maize

1973 • 40 citations

Studies on H-O Variants in Salmonella in Relation to Phase Variation

1973 • 38 citations

O o mutations in the galactose operon in E. coli

1967 • 36 citations

Genetic instability in Drosophila melanogaster

1974 • 32 citations

THE ORIGIN OF AN UNSTABLE LOCUS IN MAIZE

1968 • 28 citations

mRNA distal to polar nonsense and insertion mutations in the gal operon of E. coli

1973 • 20 citations

A role for the product of gene suA in restoration of polarity in vitro

1973 • 19 citations

gal mRNA initiated within IS2

1976 • 17 citations

Mechanism of reversion of the gal3 mutation of Escherichia coli

1975 • 15 citations

Reversion of the gal3 mutation of Escherichia coli: Partial deletion of the insertion sequence

1975 • 15 citations

Distribution of inverted IS-length sequences in the E. coli K12 genome

1976 • 14 citations

Temporary Expression of Flagellar Phase-1 in Phase-2 Clones of Diphasic Salmonella

1975 • 7 citations

Specificity of polarity suppression in E. coli: Correction of defects in gene N, but not in gene Q, of phage λ

1976 • 7 citations