Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

AU-rich elements: characterization and importance in mRNA degradation

1995 • 1,936 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

mRNA stability in mammalian cells

1995 • 1,258 citations

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the invivo stability of ARE-containing mRNAs

1998 • 852 citations

Anti-Hu-Associated Paraneoplastic Encephalomyelitis/Sensory Neuronopathy A Clinical Study of 71 Patients

1992 • 812 citations

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

1998 • 738 citations

Role of the CD28 receptor in T-cell activation

1990 • 684 citations

Hypoxic Stabilization of Vascular Endothelial Growth Factor mRNA by the RNA-binding Protein HuR

1998 • 662 citations

INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

1996 • 653 citations

Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein

1996 • 652 citations

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal

1991 • 553 citations

A nuclear export signal in hnRNP A1: A signal-mediated, temperature-dependent nuclear protein export pathway

1995 • 529 citations

Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development

1991 • 491 citations

HNS, a nuclear-cytoplasmic shuttling sequence in HuR

1998 • 465 citations

Detection of the anti‐Hu antibody in the serum of patients with small cell lung cancer—A quantitative western blot analysis

1990 • 394 citations

A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells

1991 • 381 citations

The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein

1997 • 371 citations

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

1993 • 356 citations

Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta- cytoplasmic actin messenger RNAs to different cytoplasmic compartments [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 2):following 1907]

1993 • 332 citations

The 3′-untranslated region of CaMKIIα is a cis-acting signal for the localization and translation of mRNA in dendrites

1996 • 322 citations

A conserved family of elav-like genes in vertebrates.

1995 • 309 citations

The elav Gene Product of Drosophila , Required in Neurons, Has Three RNP Consensus Motifs

1988 • 302 citations

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

1997 • 302 citations

Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brain.

1996 • 273 citations

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

1991 • 268 citations

ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system

1999 • 244 citations

Sequential expression and role of Hu RNA-binding proteins during neurogenesis

1997 • 240 citations

Getting the message from the gene to the synapse: sorting and intracellular transport of RNA in neurons

1992 • 235 citations

Embryonic Lethal Abnormal Visual RNA-Binding Proteins Involved in Growth, Differentiation, and Posttranscriptional Gene Expression

1997 • 233 citations

ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation

1998 • 227 citations

Ectopic Expression of Hel-N1, an RNA-Binding Protein, Increases Glucose Transporter (GLUT1) Expression in 3T3-L1 Adipocytes

1997 • 200 citations

The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

1987 • 177 citations

Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor

1994 • 168 citations

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.

1994 • 153 citations

Messenger ribonucleoprotein complexes containing human ELAV proteins: interactions with cytoskeleton and translational apparatus

1998 • 136 citations

Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation

1996 • 122 citations

Nuclear RNA export

1998 • 114 citations

Regulation of proto-oncogene mRNA stability

1992 • 111 citations

Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

1993 • 108 citations

AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation

1997 • 92 citations

A 32-Kilodalton Protein Binds to AU-Rich Domains in the 3′ Untranslated Regions of Rapidly Degraded mRNAs

1991 • 81 citations

Autoimmune pathogenesis of paraneoplastic neurological syndromes.

1987 • 77 citations

Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.

1992 • 72 citations

mRNA Formation and Function

1997 • 60 citations