Heme Histidine Ligands within gp91 Modulate Proton Conduction by the Phagocyte NADPH Oxidase

NADPH Oxidase: An Update

1999 • 2,134 citations

The respiratory burst oxidase.

1994 • 608 citations

Molecular mechanisms for proton transport in membranes.

1978 • 566 citations

Enzymic mechanisms of superoxide production

1991 • 475 citations

The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel

1987 • 335 citations

A Mammalian H ⁺ Channel Generated Through Alternative Splicing of the NADPH Oxidase Homolog NOH-1

2000 • 295 citations

Voltage-Dependent Proton Transport by the Voltage Sensor of the Shaker K+ Channel

1997 • 224 citations

NADPH oxidase of neutrophils

1996 • 208 citations

Gp91 ^phox is the heme binding subunit of the superoxide-generating NADPH oxidase

1998 • 198 citations

Potential, pH, and arachidonate gate hydrogen ion currents in human neutrophils

1993 • 170 citations

Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils

1989 • 170 citations

Processing and Maturation of Flavocytochromeb 558 Include Incorporation of Heme as a Prerequisite for Heterodimer Assembly

2000 • 163 citations

Ph-Dependent Inhibition of Voltage-Gated H+ Currents in Rat Alveolar Epithelial Cells by Zn2+ and Other Divalent Cations

1999 • 159 citations

Biosynthesis of the Phagocyte NADPH Oxidase Cytochromeb 558

1997 • 156 citations

Succinylacetone, a potent inhibitor of heme biosynthesis: Effect on cell growth, heme content and δ-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells

1979 • 151 citations

Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils

2000 • 137 citations

Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge.

1988 • 132 citations

Intracellular pH regulation during spreading of human neutrophils.

1996 • 128 citations

A Novel H+ Conductance in Eosinophils

1999 • 127 citations

Proton currents in human granulocytes: regulation by membrane potential and intracellular pH.

1993 • 124 citations

The Arachidonate-activable, NADPH Oxidase-associated H+ Channel

1995 • 104 citations

The NADPH Oxidase of Phagocytic Leukocytes^a

1997 • 93 citations

The arachidonate-activatable, NADPH oxidase-associated H+ channel is contained within the multi-membrane-spanning N-terminal region of gp91-phox

1997 • 79 citations

Biosynthesis of Flavocytochrome b 558

1999 • 74 citations

The NADPH-oxidase-associated H+ channel is opened by arachidonate

1992 • 69 citations

Intracellular application of guanosine-5'-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils.

1990 • 66 citations

Evidence That the Product of the Human X-Linked Cgd Gene, Gp91-phox, Is a Voltage-Gated H+ Pathway

1999 • 66 citations

Electron Transfer Across the O₂^- Generating Flavocytochrome b of Neutrophils. Evidence for a Transition from a Low-Spin State to a High-Spin State of the Heme Iron Component

1996 • 65 citations

Essential Requirement of Cytosolic Phospholipase A2for Activation of the H+ Channel in Phagocyte-like Cells

1999 • 57 citations

Role of Histidines Identified by Mutagenesis in the NADPH Oxidase-associated H+ Channel

1998 • 56 citations

Studies on the electron-transfer mechanism of the human neutrophil NADPH oxidase

1989 • 42 citations

Biochemical and immunochemical properties of B lymphocyte cytochrome b558

1998 • 39 citations

The role of small GTP-binding proteins in leukocyte function

1994 • 39 citations

Adenovirus-mediated gene transfer into monocyte-derived macrophages of patients with X-linked chronic granulomatous disease: ex vivo correction of deficient respiratory burst

1997 • 38 citations

Kinetic Study of the Activation of the Neutrophil NADPH Oxidase by Arachidonic Acid. Antagonistic Effects of Arachidonic Acid and Phenylarsine Oxide

1999 • 36 citations

Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox function.

1994 • 35 citations

Four varieties of voltage-gated proton channels

1998 • 32 citations

The NADPH Oxidase: Lessons from Chronic Granulomatous Disease Neutrophils

1997 • 13 citations