Mechanisms of spontaneous mutation in DNA repair-proficient Escherichia coli

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

1988 • 3,957 citations

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

Rate of depurination of native deoxyribonucleic acid

1972 • 1,488 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

The origin of mutants

1988 • 1,029 citations

Complementary base pairing and the origin of substitution mutations

1976 • 835 citations

Heat-induced deamination of cytosine residues in deoxyribonucleic acid

1974 • 725 citations

On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletions

1982 • 690 citations

ON THE TOPOGRAPHY OF THE GENETIC FINE STRUCTURE

1961 • 576 citations

Genetic studies of the lac repressor

1978 • 517 citations

Sequence of the lacI gene

1978 • 463 citations

DNA MISMATCH CORRECTION

1987 • 427 citations

Mutational specificity of depurination.

1984 • 361 citations

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

1989 • 316 citations

Mechanisms of spontaneous mutagenesis: An analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene

1986 • 305 citations

The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.

1986 • 301 citations

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

1987 • 291 citations

Mutagenic specificity of ultraviolet light

1985 • 282 citations

Structure and function of the F factor and mechanism of conjugation

1987 • 272 citations

Nucleic acids and nuclear magnetic resonance

1988 • 269 citations

Spontaneous Mutation: Comparative Rates of Spontaneous Mutation

1969 • 268 citations

Structural intermediates of deletion mutagenesis: a role for palindromic DNA.

1984 • 251 citations

FRAMESHIFT MUTATION: DETERMINANTS OF SPECIFICITY

1990 • 238 citations

Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.

1988 • 203 citations

Kinetic basis of spontaneous mutation

1982 • 187 citations

DNA sequence at the integration sites of the insertion element IS1

1978 • 158 citations

Specificity of mutagenesis resulting from the induction of the SOS system in the absence of mutagenic treatment

1984 • 146 citations

Repair of DNA Base-pair Mismatches in Extracts of Escherichia coli

1984 • 109 citations

Chi hotspots of generalized recombination

1983 • 106 citations

Recent studies of the fidelity of DNA synthesis

1988 • 98 citations

Genetic studies of the lac repressor

1977 • 91 citations

Missense mutation in the lacI gene of Escherichia coli

1988 • 87 citations

Z-DNA-forming sequences are spontaneous deletion hot spots.

1989 • 87 citations

Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae.

1989 • 77 citations

Deletion formation in bacteriophage T4

1988 • 75 citations

Much of spontaneous mutagenesis in Escherichia coli is due to error-prone DNA repair: implications for spontaneous carcinogenesis

1981 • 58 citations

Asymmetric cytosine deamination revealed by spontaneous mutational specificity in an Ung− strain of Escherichia coli

1987 • 54 citations

Escherichia coli mutator mutD5 is defective in the mutHLS pathway of DNA mismatch repair.

1989 • 53 citations

Kinetics of base misinsertion by DNA polymerase I of Escherichia coli

1983 • 44 citations

DNA sequence analysis of spontaneous mutation in a PolA1 strain of Escherichia coli indicates sequence-specific effects

1987 • 42 citations

DNA replication fidelity: kinetics and thermodynamics

1988 • 37 citations

Deoxyuridine misincorporation causes site-specific mutational lesions in the lacI gene of Escherichia coli

1986 • 37 citations

Specificity of recA441-mediated (tif-1) mutational events

1991 • 24 citations

Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase.

1987 • 23 citations

An analysis of sequence repeats in the lacI gene of Escherichia coli

1978 • 22 citations

Distribution and specificity of mutations induced by neocarzinostatin in the lacI gene of Escherichia coli

1983 • 20 citations

Protein domain structure influences observed distribution of mutation

1988 • 20 citations

Colony hybridisation in escherichia coli: A rapid procedure for determining the distribution of specific classes of mutations among a number of preselected sites

1990 • 17 citations

DNA sequence analysis of spontaneous histidine mutations in a polA1 strain of Escherichia coli K12 suggests a specific role of the GTGG sequence

1990 • 12 citations

Spontaneous and 9-aminoacridine-induced frameshift mutagenesis: second-site frameshift mutation within the N-terminal region of thelacI gene ofEscherichia coli

1991 • 12 citations

Mutational specificity of thymine deprivation-induced mutation in the lacI gene of Escherichia coli

1988 • 6 citations