Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Fidelity of DNA Synthesis

1982 • 516 citations

DNA MISMATCH CORRECTION

1987 • 427 citations

Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.

1980 • 391 citations

Mutational specificity of depurination.

1984 • 361 citations

BACTERIAL MUTATOR GENES AND THE CONTROL OF SPONTANEOUS MUTATION

1976 • 342 citations

Mechanisms of spontaneous mutagenesis: An analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene

1986 • 305 citations

The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.

1986 • 301 citations

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

1987 • 291 citations

Spontaneous Mutation: Comparative Rates of Spontaneous Mutation

1969 • 268 citations

MISMATCH REPAIR IN ESCHERICHIA COLI

1986 • 253 citations

Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria

1986 • 252 citations

A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzyme.

1984 • 246 citations

Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication.

1983 • 212 citations

Conditional Mutator Gene in Escherichia coli : Isolation, Mapping, and Effector Studies

1974 • 201 citations

Mutational specificity of a conditional Escherichia coli mutator, mutD5

1974 • 200 citations

Kinetic basis of spontaneous mutation

1982 • 187 citations

Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme.

1983 • 174 citations

Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma.

1988 • 167 citations

Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunits.

1987 • 132 citations

Repair of DNA Base-pair Mismatches in Extracts of Escherichia coli

1984 • 109 citations

Rapid repeated cloning of mutant lac repressor genes

1985 • 101 citations

Correlation of lac operator DNA imino proton exchange kinetics with its function.

1984 • 76 citations

The interaction of DNA polymerase III and the product of the Escherichia coli mutator gene, mutD.

1984 • 73 citations

Nucleoside triphosphate binding to DNA polymerase III holoenzyme of Escherichia coli. A direct photoaffinity labeling study.

1984 • 65 citations

DOMINANT MUTATORS IN ESCHERICHIA COLI

1982 • 65 citations

Characterization of mutational specificity within the lacI gene for a mutD5 mutator strain of Escherichia coli defective in 3'----5' exonuclease (proofreading) activity

1986 • 57 citations

Escherichia coli mutT mutator effect during in vitro DNA synthesis. Enhanced A.G replicational errors.

1987 • 57 citations

Colony probing as an alternative to standard sequencing as a means of direct analysis of chromosomal DNA to determine the spectrum of single-base changes in regions of known sequence.

1986 • 55 citations

A dominant (mut D5) and a recessive (dnaQ49) mutator of Escherichia coli

1983 • 55 citations

Mutation rate : Some biological and biochemical considerations

1982 • 52 citations

Possible Molecular Detent in the DNA Structure at Regulatory Sequences

1983 • 45 citations

DNA sequence analysis of spontaneous mutation in a PolA1 strain of Escherichia coli indicates sequence-specific effects

1987 • 42 citations

DNA sequence and coding properties of mutD(dnaQ) a dominant Escherichia coli mutator gene

1986 • 37 citations

Mutational specificity of a proof-reading defective Escherichia coli dnaQ49 mutator

1986 • 24 citations

Interaction of an Escherichia coli mutator gene with a deoxyribonucleotide effector

1980 • 23 citations

Conditionallethality of Escherichia coli strains carrying dnaE anddnaQ mutations

1981 • 15 citations