DNA sequence analysis of spontaneous mutation in a PolA1 strain of Escherichia coli indicates sequence-specific effects

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

ACETYLORNITHINASE OF ESCHERICHIA COLI: PARTIAL PURIFICATION AND SOME PROPERTIES

1956 • 4,156 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Complementary base pairing and the origin of substitution mutations

1976 • 835 citations

Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase

1969 • 749 citations

On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletions

1982 • 690 citations

The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites

1984 • 673 citations

Genetic studies of the lac repressor

1978 • 517 citations

Sequence of the lacI gene

1978 • 463 citations

Mutational specificity of depurination.

1984 • 361 citations

Molecular Basis of Mutation

1970 • 349 citations

THE MOLECULAR BASIS OF MUTATION

1972 • 315 citations

Mechanisms of spontaneous mutagenesis: An analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene

1986 • 305 citations

Structural intermediates of deletion mutagenesis: a role for palindromic DNA.

1984 • 251 citations

Genetic Analysis of an E. coli Strain with a Mutation affecting DNA Polymerase

1969 • 223 citations

Spontaneous Mutation: Genetic Control of Mutation Rates in Bacteriophage T4

1969 • 206 citations

Model for the participation of quasi-palindromic DNA sequences in frameshift mutation.

1982 • 199 citations

Induced mutagenesis in dam − mutants of Escherichia coli: A role for 6-methyladenine residues in mutation avoidance

1978 • 198 citations

On the Role of DNA Polymerase in Base Selection

1966 • 118 citations

Sites of reaction of Escherichia coli DNA gyrase on pBR322 in vivo as revealed by oxolinic acid-induced plasmid linearization

1985 • 117 citations

Repair of DNA Base-pair Mismatches in Extracts of Escherichia coli

1984 • 109 citations

Chi hotspots of generalized recombination

1983 • 106 citations

Rapid repeated cloning of mutant lac repressor genes

1985 • 101 citations

Unique Self-complementarity of Palindromic Sequences Provides DNA Structural Intermediates for Mutation

1983 • 93 citations

Genetic studies of the lac repressor

1977 • 91 citations

Increased Frequency of Deletions in DNA Polymerase Mutants of Escherichia coli

1970 • 87 citations

Spontaneous mutagenesis: the roles of DNA repair, replication, and recombination

1985 • 79 citations

Correlation of lac operator DNA imino proton exchange kinetics with its function.

1984 • 76 citations

Genetic mapping and DNA sequence analysis of mutations in the polA gene of Escherichia coli

1985 • 68 citations

Much of spontaneous mutagenesis in Escherichia coli is due to error-prone DNA repair: implications for spontaneous carcinogenesis

1981 • 58 citations

Characterization of mutational specificity within the lacI gene for a mutD5 mutator strain of Escherichia coli defective in 3'----5' exonuclease (proofreading) activity

1986 • 57 citations

Isolation of an Escherichia coli K-12 dnaE mutation as a mutator

1978 • 42 citations

The reversion of trp frameshift mutations in mut, polA, lig and dnaE mutant strains of Escherichia coli

1978 • 36 citations

Increased spontaneous reversion of certain frameshift mutations in DNA polymerase I deficient strains of Escherichia coli

1975 • 30 citations

Mechanism of mutation by thymine starvation in Escherichia coli: clues from mutagenic specificity

1985 • 26 citations

Mechanisms of Spontaneous Mutagenesis: Clues from Altered Mutational Specificity in DNA Repair-Defective Strains

1986 • 16 citations

Powerful mutator activity of the polA1 mutation within the histidine region of Escherichia coli K-12.

1982 • 14 citations