Structure and function of the F factor and mechanism of conjugation

How signal sequences maintain cleavage specificity

1984 • 725 citations

Identification of a Sex-factor-affinity Site in E. coli as

1981 • 576 citations

DNA: Insertion Elements, Plasmids, and Episomes.

1977 • 530 citations

arcA (dye), a global regulatory gene in Escherichia coli mediating repression of enzymes in aerobic pathways.

1988 • 416 citations

Processing of plasmid DNA during bacterial conjugation

1984 • 341 citations

Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli

1973 • 339 citations

PROTEIN SECRETION IN ESCHERICHIA COLI

1985 • 334 citations

THE CONJUGATION SYSTEM OF F-LIKE PLASMIDS

1980 • 312 citations

SEX COMPATIBILITY IN ESCHERICHIA COLI

1952 • 310 citations

Phylogenetic relationships of drug-resistance factors and other transmissible bacterial plasmids

1968 • 303 citations

BASIC PROCESSES UNDERLYING AGROBACTERIUM-MEDIATED DNA TRANSFER TO PLANT CELLS

1988 • 289 citations

Specification of surface mating systems among conjugative drug resistance plasmids in Escherichia coli K-12

1980 • 257 citations

THE CONJUGATION SYSTEM OF F, THE FERTILITY FACTOR OF ESCHERICHIA COLI

1986 • 218 citations

Con ⁻ Mutants: Class of Mutants in Escherichia coli K-12 Lacking a Major Cell Wall Protein and Defective in Conjugation and Adsorption of a Bacteriophage

1974 • 190 citations

Morphological and serological relationships of conjugative pili

1980 • 180 citations

Electron microscope heteroduplex studies of sequence relations among bacterial plasmids: identification and mapping of the insertion sequences IS1 and IS2 in F and R plasmids

1975 • 174 citations

Plasmid-determined resistance to serum bactericidal activity: a major outer membrane protein, the traT gene product, is responsible for plasmid-specified serum resistance in Escherichia coli

1980 • 172 citations

Observations on a Transmissible Agent Determining Sexual Differentiation in Bacterium coli

1953 • 170 citations

Agrobacterium tumefaciens and the susceptible plant cell: A novel adaptation of extracellular recognition and DNA conjugation

1986 • 169 citations

The Physiology and Biochemistry of Pili

1988 • 158 citations

The adsorption of bacteriophage R-17

1964 • 151 citations

An Infective Factor Controlling Sex Compatibility in Bacterium coli

1953 • 144 citations

The attachment of the male-specific bacteriophage F1 to sensitive strains of Escherichia coli.

1966 • 142 citations

The Properties of Sex pili, The Viral Nature of “Conjugal” Genetic Transfer Systems, and Some Possible Approaches to the Control of Bacterial Drug Resistance

1971 • 140 citations

Sex Pili and the Classification of Sex Factors in the Enterobacteriaceae

1967 • 131 citations

Bacterial outer membranes as model systems

1987 • 131 citations

Characterisation of an in vivo system for nicking at the origin of conjugal DNA transfer of the sex factor F

1980 • 128 citations

The transcriptional control of fertility in F-like plasmids

1977 • 127 citations

The requirements for conjugal DNA synthesis in the donor strain during Flac transfer

1978 • 117 citations

Repressor gene finO in plasmids R100 and F: constitutive transfer of plasmid F is caused by insertion of IS3 into F finO

1987 • 117 citations

R Factors from Proteus morganii

1973 • 114 citations

The Cpx proteins of Escherichia coli K12

1988 • 110 citations

Molecular cloning of DNA from F sex factor of Escherichia coli K-12.

1976 • 106 citations

Two classes of Flac mutants insensitive to transfer inhibition by an F-like R factor

1971 • 102 citations

Evidence for two mechanisms for DNA unwinding catalyzed by DNA helicases.

1979 • 102 citations

Asymmetric Transfer of DNA Strands in Bacterial Conjugation

1968 • 101 citations

DNA sequence analysis of the dye gene of Escherichia coli reveals amino acid homology between the dye and OmpR proteins.

1985 • 101 citations

Retraction of F Pili

1974 • 93 citations

DNA sequence of the F traALE region that includes the gene for F pilin

1984 • 93 citations

Genetic Analysis of Transfer by the Escherichia coli Sex Factor F, Using P1 Transductional Complementation

1972 • 93 citations

Relationship between chromosome replication and F′lac episome replication in Escherichia coli

1973 • 93 citations

TRANSFER-DEFECTIVE MUTANTS OF SEX FACTORS IN ESCHERICHIA COLI. I. DEFECTIVE MUTANTS AND COMPLEMENTATION ANALYSIS

1970 • 93 citations

Escherichia coli DNA helicase I catalyzes a unidirectional and highly processive unwinding reaction.

1988 • 91 citations

Chromosomal mutations of Escherichia coli that alter expression of conjugative plasmid functions.

1980 • 90 citations

The site of action of the F transfer inhibitor

1973 • 90 citations

Electron microscopic heteroduplex studies of sequence relations among plasmids of Escherichia coli: structure of F13 and related F-primes

1975 • 89 citations

Evidence that TraT interacts with OmpA of Escherichia coli

1986 • 88 citations

Surface Components of Escherichia coli That Mediate Resistance to the Bactericidal Activities of Serum and Phagocytes

1985 • 88 citations

A review of mini-F plasmid maintenance

1985 • 86 citations

Replication and incompatibility of F and plasmids in the IncFI group

1981 • 85 citations

Two Escherichia coli chromosomal cistrons, sfrA and sfrB, which are needed for expression of F factor tra functions

1979 • 85 citations

Role of Pili in Bacterial Conjugation

1970 • 84 citations

Evidence that DNA helicase I and oriT site-specific nicking are both functions of the F TraI protein

1988 • 83 citations

Conjugation deficient E. coli K12 F- mutants with heptose-less lipopolysaccharide

1976 • 82 citations

Specificities of IncF plasmid conjugation genes

1986 • 82 citations

sfrA and sfrB products of Escherichia coli K-12 are transcriptional control factors

1981 • 81 citations

Regulation of the F conjugation genes studied by hybridization and tra-lacZ fusion

1983 • 80 citations

F sex factor encodes a single-stranded DNA binding protein (SSB) with extensive sequence homology to Escherichia coli SSB.

1983 • 80 citations

The F plasmid origin of transfer: DNA sequence of wild-type and mutant origins and location of origin-specific nicks.

1984 • 79 citations

Determination of pili by conjugative bacterial drug resistance plasmids of incompatibility groups B, C, H, J, K, M, V, and X

1980 • 78 citations

Deletion Map of the Escherichia coli K-12 Sex Factor F: the Order of Eleven Transfer Cistrons

1972 • 73 citations

DNA transfer in bacterial conjugation

1966 • 71 citations

traT Gene Sequences, Serum Resistance and Pathogenicity-related Factors in Clinical Isolates of Escherichia coli and Other Gram-negative Bacteria

1985 • 71 citations

Outer membrane of Escherichia coli: properties of the F sex factor traT protein which is involved in surface exclusion

1980 • 71 citations

Location of an F-pilin pool in the inner membrane

1981 • 70 citations

Nucleotide sequence analysis of RepFIC, a basic replicon present in IncFI plasmids P307 and F, and its relation to the RepA replicon of IncFII plasmids

1987 • 69 citations

The number of sex-factors per chromosome in Escherichia coli

1971 • 69 citations

Nucleotide sequence and transcriptional analysis of a third function (Flm) involved in F-plasmid maintenance

1988 • 69 citations

The product of the F sex factor traT surface exclusion gene is a lipoprotein.

1984 • 67 citations

Nucleotide sequence analysis of the complement resistance gene from plasmid R100

1982 • 67 citations

DNA transfer occurs during a cell surface contact stage of F sex factor-mediated bacterial conjugation

1985 • 66 citations

Five control systems preventing transfer of Escherichia coli K-12 sex factor F

1975 • 65 citations

PsiB polypeptide prevents activation of RecA protein in Escherichia coli

1988 • 65 citations

A gene encoding an SOS inhibitor is present in different conjugative plasmids

1988 • 64 citations

The nature of the transfer inhibitor of several F-like plasmids

1972 • 62 citations

Inhibition of Bacterial Conjugation by Ribonucleic Acid and Deoxyribonucleic Acid Male-Specific Bacteriophages

1968 • 61 citations

Distribution of basic replicons having homology with RepFIA, RepFIB, and RepFIC among IncF group plasmids

1986 • 61 citations

traG protein of the F sex factor of Escherichia coli K-12 and its role in conjugation

1981 • 61 citations

Characterization and sequence analysis of pilin from F-like plasmids

1985 • 60 citations

F sex factor of Escherichia coli K-12 codes for a single-stranded DNA binding protein.

1983 • 59 citations

DNA isolated from Escherichia coli minicells mated with F+ cells.

1968 • 58 citations

Promoter mapping and DNA sequencing of the F plasmid transfer genes traM and traJ

1982 • 57 citations

Purification and characterization of F pili from Escherichia coli

1977 • 56 citations

Location of the Origin of Transfer of the Sex Factor F

1972 • 53 citations

The effect of tra mutations on the synthesis of the F-pilin membrane polypeptide

1981 • 52 citations

Surface exclusion genes traS and traT of the F sex factor of Escherichia coli K-12

1987 • 52 citations

Role of Adhesion Zones in Bacterial Cell-Surface Function and Biogenesis

1975 • 51 citations

The control region of the F plasmid transfer operon: DNA sequence of the traJ and traY genes and characterisation of the traY → Z promoter

1983 • 51 citations

Genetic analysis of Escherichia coli K-12 chromosomal mutants defective in expression of F-plasmid functions: identification of genes cpxA and cpxB

1980 • 50 citations

Promoters in the Transfer Region of Plasmid F

1985 • 49 citations

Nucleotide sequences of five IncF plasmid finP alleles

1986 • 49 citations

Conjugation-deficient mutants of Escherichia coli distinguish classes of functions of the outer membrane OmpA protein

1982 • 49 citations

The F Plasmid Carries an IS3 Insertion Within finO

1986 • 49 citations

Comparative Biochemical Studies on F and EDP208 Conjugative Pili

1980 • 48 citations

Revised genetic map of the distal end of the F transfer operon: implications for DNA helicase I, nicking at oriT, and conjugal DNA transport

1987 • 47 citations

Conjugative plasmids of enteric bacteria from many different incompatibility groups have similar genes for single-stranded DNA-binding proteins

1985 • 46 citations

Identification of the structural gene for F-pilin

1976 • 46 citations

Origin of transfer of IncF plasmids and nucleotide sequences of the type II oriT, traM, and traY alleles from ColB4-K98 and the type IV traY allele from R100-1

1986 • 45 citations

Identification and characterization of four new tra cistrons on the E. coli K12 sex factor F

1978 • 45 citations

Studies on the functions of DNA helicase I and DNA helicase II of Escherichia coli.

1980 • 44 citations

Further characterization of the F fertility inhibition systems of "unusual" Fin+ plasmids

1977 • 43 citations

TRANSFER-DEFECTIVE MUTANTS OF SEX FACTORS IN ESCHERICHIA COLI. II. DELETION MUTANTS OF AN F-PRIME AND DELETION MAPPING OF CISTRONS INVOLVED IN GENETIC TRANSFER

1970 • 43 citations

Effect of Zn ²⁺ on Bacterial Conjugation: Inhibition of Mating Pair Formation

1972 • 42 citations

Fertility repression of F-like conjugative plasmids: Physical mapping of the R6-5 finO and finP cistrons and identification of the finO protein

1978 • 42 citations

4 Attachment, Ejection and Penetration Stages of the RNA Phage Infectious Process

1975 • 42 citations

Expression of F transfer functions depends on the Escherichia coli integration host factor

1987 • 41 citations

Investigations of the F conjugation gene traI:traI mutants and λtraI transducing phages

1979 • 41 citations

The sex hair of E. coli as sensory fiber, conjugation tube, or mating arm?

1967 • 40 citations

A new activity in the Ftra operon which is required for F-pilin synthesis

1982 • 39 citations

Characterization of the F transfer cistron,traL

1973 • 39 citations

Physiology of F-Pilin Synthesis and Utilization

1983 • 39 citations

Cloning and polypeptide analysis of the leading region in F plasmid DNA transfer

1983 • 39 citations

Specification of the Conjugative Pili and Surface Mating Systems of Pseudomonas Plasmids

1983 • 38 citations

The complete nucleotide sequence of the bacteriocinogenic plasmid CloDF13

1986 • 38 citations

Analysis of transfer genes and gene products within the traB-traC region of the Escherichia coli fertility factor, F

1987 • 37 citations

Structure of F-Pili: Reassessment of the symmetry

1986 • 37 citations

Cell-cell interactions in conjugating Escherichia coli: purification of F pili with biological activity.

1978 • 37 citations

Transcript analysis of the plasmid R100 traJ and finP genes

1987 • 36 citations

Inhibition of Formation ofEscherichia coliMating Pairs by f1 and MS2 Bacteriophages as Determined with a Coulter Counter

1973 • 36 citations

Characterization of complement resistance in Escherichia coli conferred by the antibiotic resistance plasmid R100.

1980 • 35 citations

Construction and characterization of multicopy plasmids containing the entire F transfer region

1980 • 35 citations

Cyclic AMP and the production of sex pili by E. coli K-12 carrying derepressed sex factors

1975 • 34 citations

The kinetics of inhibition of Flac transfer by R100 in E. coli

1974 • 34 citations

Identification and characterization of the products from the traJ and traY genes of plasmid R100

1988 • 34 citations

Overproduction, purification and characterization of the F traT protein

1984 • 33 citations

Cloning, mapping, and sequencing of plasmid R100 traM and finP genes

1986 • 33 citations

Two monoclonal antibodies specific for different epitopes within the amino-terminal region of F pilin

1986 • 33 citations

Identification of a membrane protein associated with expression of the surface exclusion region of the F transfer operon

1977 • 33 citations

Cloning and insertional inactivation of the dye (sfrA) gene, mutation of which affects sex factor F expression and dye sensitivity of Escherichia coli K-12

1983 • 32 citations

Cloning the origin of transfer region of the resistance plasmid R1.

1984 • 32 citations

Nature of the Carbohydrate and Phosphate Associated with ColB2 and EDP208 Pilin

1981 • 31 citations

Characterization of an Escherichia coli K-12 F-Con-mutant

1976 • 31 citations

Characterization of the F plasmid TraJ protein synthesized in F' and Hfr strains of Escherichia coli K-12.

1986 • 31 citations

Nucleotide sequence of the surface exclusion genes traS and traT from the IncF0 lac plasmid pED208

1986 • 31 citations

oriT sequence of the antibiotic resistance plasmid R100

1987 • 30 citations

Nucleotide sequences of the R1-19 plasmid transfer genes traM, finP, traJ, and traY and the traYZ promoter

1986 • 30 citations

Interactions between the F conjugal transfer system and CloDF13::TnA plasmids

1980 • 29 citations

Genes and Gene Products Involved in the Synthesis of F-Pili

1985 • 29 citations

Antigen-antibody interaction. The immunodominant region of EDP208 pili.

1985 • 29 citations

An essential gene for replication of the mini-F plasmid from origin I

1984 • 28 citations

Identification of psiB genes of plasmids F and R6-5. Molecular basis for psiB enhanced expression in plasmid R6-5

1988 • 28 citations

DNA synthesis during bacterial conjugation

1973 • 28 citations

Purification and characterization of pro-TraTp, the signal sequence-containing precursor of a secreted protein encoded by the F sex factor

1984 • 28 citations

Analysis of Escherichia coli K12 F factor transfer genes: traQ, trbA, and trbB

1987 • 27 citations

Derepression of single-stranded DNA-binding protein genes on plasmids derepressed for conjugation, and complementation of an E. coli ssb -mutation by these genes

1986 • 27 citations

F factor inhibition of conjugal transfer of broad-host-range plasmid RP4: requirement for the protein product of pif operon regulatory gene pifC

1985 • 27 citations

Analysis of the promoter-distal region of the tra operon of the F sex factor of Escherichia coli K-12 encoded by EcoRI restriction fragments f17, f19, and f2

1982 • 27 citations

Conjugational synthesis of F lac + and Col I DNA in the presence of Rifampicin and in Escherichia coli K12 mutants defective in DNA synthesis

1974 • 26 citations

Chromosomal regulation of sexual expression in Escherichia coli

1979 • 26 citations

Integration host factor and conjugative transfer of the antibiotic resistance plasmid R100

1987 • 26 citations

Nucleotide sequence of the tra YALE region from IncFV plasmid pED208

1986 • 25 citations

Transfer inhibition of RP4 by F factor

1983 • 25 citations

DNA sequence analysis of point mutations in traA, the F pilin gene, reveal two domains involved in F-specific bacteriophage attachment

1988 • 25 citations

STRAND-SPECIFIC TRANSFER OF DONOR DNA DURING CONJUGATION IN E. coli

1969 • 25 citations

The traM gene of the resistance plasmid R1: comparison with the corresponding sequence of the Escherichia coli F factor

1985 • 24 citations

A traC mutant that retains sensitivity to f1 bacteriophage but lacks F pili

1987 • 24 citations

The spread of plasmids in model populations of Escherichia coli K12

1978 • 24 citations

Outer membrane of Escherichia coli K-12: differentiation of proteins 3A and 3B on acrylamide gels and further characterization of con (tolG) mutants

1976 • 24 citations

Unrelated conjugative plasmids have sequences which are homologous to the leading region of the F factor

1986 • 23 citations

Synthesis of F-pilin polypeptide in the absence of F traJ product

1984 • 22 citations

Location of the antigenic determinants of conjugative F-like pili

1986 • 22 citations

Cellular control of conjugation in Escherichia coli K12

1982 • 22 citations

Identification of the dye gene product, mutational loss of which alters envelope protein composition and also affects sex factor F expression in Escherichia coli K-12

1984 • 21 citations

Monoclonal antibody detection of IncF group plasmid-encoded TraT protein in clinical isolates of Escherichia coli

1984 • 21 citations

Major antigenic determinants of F and ColB2 pili

1985 • 20 citations

Aspects of plasmid F maintenance in Escherichia coli

1988 • 20 citations

Unusual Arsenate Poisoning of the F Pili of Escherichia coli

1973 • 20 citations

Contribution of the traT Gene to Serum Resistance Among Clinical Isolates of Enterobacteriaceae

1985 • 19 citations

An F-derived conjugative cosmid: Analysis of tra polypeptides in cosmid-infected cells

1986 • 18 citations

The product of the F plasmid transfer operon gene, traF, is a periplasmic protein

1988 • 18 citations

Fertllity inhibition gene of plasmid R100

1987 • 17 citations

Clo DF13 plasmid genes affecting Flac transfer and propagation of male specific RNA phages

1979 • 16 citations

The sequences of the traJ gene and the 5′ end of the traY gene of the resistance plasmid R1

1986 • 16 citations

Location of F plasmid transfer operon genes traC and traW and identification of the traW product

1987 • 16 citations

Characterisation of a λ transducing phage carrying the F conjugation gene traG

1980 • 15 citations

traJ independence in expression of traT on F

1983 • 14 citations

Selection of Escherichia coli K-12 chromosomal mutants that prevent expression of F-plasmid functions

1980 • 14 citations

Shadow promoters in the F plasmid transfer operon

1986 • 14 citations

Structure and nucleotide sequence of the region encoding the mobilization proteins of plasmid CloDF13

1987 • 14 citations

F- mating materials able to generate a mating signal in mating with HfrH dnaB(Ts) cells

1978 • 13 citations

Cyclic AMP and its receptor protein are required for expression of transfer genes of conjugative plasmid F in Escherichia coli

1983 • 13 citations

The origin of transfer of P307

1987 • 12 citations

Another gene affecting sexual expression of Escherichia coli

1982 • 11 citations

Transfer gene expression during fertility inhibition of the Escherichia coli K12 sex factor F by the I-like plasmid R62

1976 • 10 citations

Expression of F plasmid trat: Independence of tray → z promoter and traJ control

1986 • 9 citations

Location of a second partitioning region (ParL) on the F plasmid

1986 • 8 citations

Effect of an Escherichia coli traD (ts) Mutation on MS2 RNA Replication

1983 • 4 citations