Z-DNA-forming sequences are spontaneous deletion hot spots.

Molecular structure of a left-handed double helical DNA fragment at atomic resolution

1979 • 2,057 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 inEscherichia coliK-12

1987 • 362 citations

Energetics of B-to-Z transition in DNA.

1983 • 335 citations

Facile transition of poly[d(TG)·d(CA)] into a left-handed helix in physiological conditions

1983 • 335 citations

Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling.

1982 • 321 citations

Use of site-specific recombination as a probe of DNA structure and metabolism in vivo

1987 • 297 citations

Left-handed DNA in restriction fragments and a recombinant plasmid

1981 • 277 citations

Left-Handed DNA in Vivo

1987 • 214 citations

Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli

1984 • 183 citations

Hot spots of frameshift mutations induced by the ultimate carcinogen N- acetoxy-N-2-acetylaminofluorene

1981 • 164 citations

Unwinding of double-stranded DNA helix by dehydration.

1981 • 160 citations

Transcriptional block caused by a negative supercoiling induced structural change in an alternating CG sequence

1985 • 160 citations

Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues.

1981 • 143 citations

Transition of a cloned d(AT)n-d(AT)n tract to a cruciformin vivo

1985 • 130 citations

Conformation of poly(dG-dC) . poly(dG-dC) modified by the carcinogens N-acetoxy-N-acetyl-2-aminofluorene and N-hydroxy-N-2-aminofluorene.

1980 • 129 citations

(A-T)_ntracts embedded in random sequence DNA — formation of a structure which is chemically reactive and torsionally deformable

1986 • 113 citations

Left-handed DNA and the synaptic pairing reaction promoted by ustilago recl protein

1985 • 113 citations

Left-handed DNA. Cloning, characterization, and instability of inserts containing different lengths of (dC-dG) in Escherichia coli.

1982 • 98 citations

DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum

1984 • 96 citations

The B- to Z-DNA equilibrium in vivo is perturbed by biological processes.

1988 • 90 citations

Evidence of cruciform structures in superhelical DNA provided by two‐dimensional gel electrophoresis

1983 • 75 citations

Conformational changes of poly(dG-dC). poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene

1981 • 74 citations

Methyl-directed repair of frameshift mutations in heteroduplex DNA.

1986 • 65 citations

Z-DNA conformation of N-2-acetylaminofluorene modified poly(dG-dC)·poly(dG-dC) determined by reactivity with anti cytidine antibodies and minimized potential energy calculations

1981 • 55 citations

A two-state conformational equilibrium for alternating (A-T)n sequences in negatively supercoiled DNA

1987 • 52 citations

Bacterial chromatin: A new twist to an old story

1986 • 50 citations

Construction of frameshift mutation hot spots within the tetracycline resistance gene of pBR322

1985 • 30 citations

Stochastic distribution of a short region of Z-DNA within a long repeated sequence in negatively supercoiled plasmids.

1988 • 23 citations