Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity.

Molecular Cloning: A Laboratory Manual

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Molecular cloning: A laboratory manual

1990 • 85,659 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Oxidative stress as a mediator of apoptosis

1994 • 2,210 citations

THIOREDOXIN

1985 • 1,885 citations

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1983 • 1,808 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Persistent oxidative stress in cancer

1995 • 1,218 citations

Thioredoxin-dependent peroxide reductase from yeast.

1994 • 940 citations

[21] Thioredoxin and thioredoxin reductase

1995 • 932 citations

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.

1992 • 912 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 898 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair.

1994 • 646 citations

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1982 • 610 citations

Overexpression of Metallothionein Confers Resistance to Anticancer Drugs

1988 • 600 citations

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1993 • 581 citations

The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase.

1994 • 361 citations

Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols

1995 • 315 citations

Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma.

1994 • 280 citations

Cisplatin Generates Superoxide Anion by Interaction with DNA in a Cell-Free System

1994 • 255 citations

Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide

1994 • 252 citations

Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines.

1992 • 242 citations

Characterization of the reactions of platinum antitumor agents with biologic and nonbiologic sulfur-containing nucleophiles

1987 • 241 citations

Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide.

1995 • 240 citations

Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis.

1995 • 239 citations

Induction of fos RNA by DNA-damaging agents.

1989 • 209 citations

Cisplatin-induced lipid peroxidation and decrease of gluconeogenesis in rat kidney cortex: Different effects of antioxidants and radical scavengers

1988 • 208 citations

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells.

1991 • 201 citations

1-Chloro-2,4-dinitrobenzene Is an Irreversible Inhibitor of Human Thioredoxin Reductase

1995 • 185 citations

Reactive oxygen-reducing and protein-refolding activities of adult t cell leukemia-derived factor /human thioredoxin

1992 • 176 citations

Metallothionein-mediated cisplatin resistance in human ovarian carcinoma cells

1987 • 175 citations

Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation

1992 • 166 citations

Modulation of cis-diamminedichloroplatinum(II) resistance: a review

1992 • 161 citations

Expression and growth-promoting effect of adult t-cell leukemia-derived factor a human thioredoxin homologue in hepatocellular carcinoma

1992 • 145 citations

The predicted amino acid sequence of human thioredoxin is identical to that of the autocrine growth factor human adult T-cell derived factor (ADF): Thioredoxin mRNA is elevated in some human tumors

1994 • 141 citations

Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism

1992 • 138 citations

The role of glutathione in resistance to cisplatin in a human small cell lung cancer cell line

1990 • 123 citations

Rapid and Preferential Activation of the c-jun Gene during the Mammalian UV Response

1991 • 120 citations

Amelioration of cis-platinum nephrotoxicity by orgotein (superoxide dismutase).

1978 • 116 citations

Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells

1995 • 115 citations

Thiol-mediated redox regulation of lymphocyte proliferation. Possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression.

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Thymosin Fraction V and Intensive Combination Chemotherapy

1979 • 108 citations

In Vivo and in Vitro binding of platinum to metallothionein

1984 • 107 citations

Modification of Cisplatin Toxicity by Antioxidants

1986 • 105 citations

Coexpression of adult T-cell leukemia-derived factor, a human thioredoxin homologue, and human papillomavirus DNA in neoplastic cervical squamous epithelium

1991 • 104 citations

Purification of human thioredoxin reductase: Properties and characterization by absorption and circular dichroism spectroscopy

1993 • 96 citations

Neuroprotection by glial cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX)

1994 • 93 citations

IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor.

1988 • 90 citations

cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.

1992 • 72 citations

Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent.

1992 • 72 citations

Increased release of hydrogen peroxide (H2O2) and superoxide anion (O2−) by murine macrophages in vitro after cis-Platin treatment

1986 • 70 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 63 citations

Detection of adult T-cell leukemia-derived factor/human thioredoxin in human serum

1994 • 25 citations

Stereoselective, strong inhibition of ribonucleotide reductase from E. coli by cisplatin

1989 • 21 citations

Hydroxyurea-induced conversion of mammalian ribonucleotide reductase to a form hypersensitive to bleomycin.

1986 • 16 citations

Adult T-cell leukaemia-derived factor/thioredoxin expression on the HTLV-I transformed T-cell lines: heterogeneous expression in ALT-2 cells.

1992 • 14 citations

Interactions of platinum complexes with thioltransferase(glutaredoxin), in vitro

1991 • 13 citations

Inhibition of mammalian ribonucleotide reductase by cis-diamminedichloroplatinum(II)

1992 • 12 citations

Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide

1994 • 10 citations

Carboplatin as opposed to cisplatin does not stimulate the expression of the human immunodeficiency virus long terminal repeat sequences

1992 • 7 citations

Adult T-cell leukemia-derived factor/thioredoxin expression on the HTLV-I transformed T-cell lines : heterogeneous expression in ATL-2 cells

1993 • 3 citations