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Hitting their targets: an emerging picture of E2F and cell cycle control

Data up to Jan 2025

Published2004
Citations134
References45

Total Citations Per Year

Abstract

References (45)

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2002 • 1,158 citations

E2F integrates cell cycle progression with DNA repair, replication, and G2/M checkpoints

2002 • 1,102 citations

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E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis

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A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

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2001 • 436 citations

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Genomic binding by theDrosophilaMyc, Max, Mad/Mnt transcription factor network

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2003 • 334 citations

E2f3 is critical for normal cellular proliferation

2000 • 323 citations

DNA Damage-Dependent Acetylation of p73 Dictates the Selective Activation of Apoptotic Target Genes

2002 • 319 citations

E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes

2003 • 264 citations

Gene expression phenotypic models that predict the activity of oncogenic pathways

2003 • 264 citations

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

2002 • 263 citations

Differential regulation of E2F1 apoptotic target genes in response to DNA damage

2003 • 262 citations

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

2001 • 248 citations

Identification and Characterization of E2F7, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation

2003 • 220 citations

E2F-6, a member of the E2F family that can behave as a transcriptional repressor

1998 • 217 citations

E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

1998 • 190 citations

Identification of a Novel E2F3 Product Suggests a Mechanism for Determining Specificity of Repression by Rb Proteins

2000 • 183 citations

Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6

1998 • 179 citations

Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

2004 • 174 citations

Gene repression by Polycomb group protein complexes: a distinct complex for every occasion?

2003 • 172 citations

E2F1 and c-Myc in Cell Growth and Death

2003 • 169 citations

Identifying cooperativity among transcription factors controlling the cell cycle in yeast

2003 • 163 citations

pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F Activities

2003 • 126 citations

E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains

2004 • 110 citations

Recent advances in computational promoter analysis in understanding the transcriptional regulatory network

2003 • 107 citations

Identification of E-Box Factor TFE3 as a Functional Partner for the E2F3 Transcription Factor

2003 • 106 citations

New roles for the RB tumor suppressor protein

2003 • 104 citations

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2003 • 104 citations

Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6

2002 • 88 citations

Insights into Innovation

2004 • 78 citations

Identification of E2F-3B, an alternative form of E2F-3 lacking a conserved N-terminal region

2000 • 77 citations

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1999 • 74 citations

Combinatorial gene control involving E2F and E Box family members

2004 • 68 citations

Binary and Graded Responses in Gene Networks

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Combinatorial transcription factors

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The role of the transcription factor DP in apoptosis.

2003 • 47 citations

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

2001 • 45 citations

A New Role for E2F-1 in Checkpoint Control

2003 • 31 citations

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Hitting their targets: an emerging picture of E2F and cell cycle control (2004) – Current Opinion in Genetics & Development | Metascience Observatory Explorer