A surprising simplicity to protein folding

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Funnels, pathways, and the energy landscape of protein folding: A synthesis

1995 • 2,607 citations

Structure and Mechanism in Protein Science

2017 • 2,079 citations

Structure and Mechanism in Protein Science. A guide to Enzyme Catalysis and Protein Folding

2001 • 1,799 citations

Contact order, transition state placement and the refolding rates of single domain proteins 1 1Edited by P. E. Wright

1998 • 1,508 citations

How do small single-domain proteins fold?

1998 • 876 citations

Theoretical Studies of Protein Folding

1983 • 831 citations

A simple model for calculating the kinetics of protein folding from three-dimensional structures

1999 • 631 citations

Ab initio protein structure prediction of CASP III targets using ROSETTA

1999 • 542 citations

"New View" of Protein Folding Reconciled with the Old Through Multiple Unfolding Simulations

1997 • 514 citations

Is protein folding hierarchic? I. Local structure and peptide folding

1999 • 493 citations

Specific Nucleus as the Transition State for Protein Folding: Evidence from the Lattice Model

1994 • 478 citations

Protein folding in the landscape perspective: Chevron plots and non-arrhenius kinetics

1998 • 447 citations

The fundamentals of protein folding: bringing together theory and experiment

1999 • 414 citations

Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures

1999 • 390 citations

Is protein folding hierarchic? II. Folding intermediates and transition states

1999 • 384 citations

Experiment and theory highlight role of native state topology in SH3 folding.

1999 • 382 citations

The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved.

1999 • 332 citations

A theoretical search for folding/unfolding nuclei in three-dimensional protein structures

1999 • 315 citations

Functional rapidly folding proteins from simplified amino acid sequences

1997 • 306 citations

A novel DNA-binding motif in MarA: The first structure for an AraC family transcriptional activator

1998 • 298 citations

Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding.

1999 • 288 citations

Conservation of rapid two-state folding in mesophilic, thermophilic and hyperthermophilic cold shock proteins

1998 • 288 citations

Pathways for protein folding: is a new view needed?

1998 • 254 citations

The energy landscape theory of protein folding: Insights into folding mechanisms and scenarios

2000 • 245 citations

Exploring the origins of topological frustration: Design of a minimally frustrated model of fragment B of protein A

1999 • 235 citations

Identification and Characterization of the Unfolding Transition State of Chymotrypsin Inhibitor 2 by Molecular Dynamics Simulations

1996 • 228 citations

Chaperone rings in protein folding and degradation

1999 • 191 citations

Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2

1996 • 174 citations

Critical assessment of methods of protein structure prediction (CASP): Round III

1999 • 173 citations

Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain

1998 • 173 citations

Matching theory and experiment in protein folding

1999 • 164 citations

Ab initio folding of proteins using restraints derived from evolutionary information

1999 • 142 citations

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site

1998 • 139 citations

Protein Structures and Optimal Folding from a Geometrical Variational Principle

1999 • 130 citations

Analysis and assessment of ab initio three‐dimensional prediction, secondary structure, and contacts prediction

1999 • 129 citations

The sequences of small proteins are not extensively optimized for rapid folding by natural selection

1998 • 125 citations

First principles prediction of protein folding rates 1 1Edited by F. E. Cohen

1999 • 111 citations

Variational Theory for Site Resolved Protein Folding Free Energy Surfaces

1998 • 107 citations

Protein Folding Dynamics: Quantitative Comparison between Theory and Experiment

1998 • 98 citations

Analysis and assessment of ab initio three-dimensional prediction, secondary structure, and contacts prediction

1999 • 81 citations

Structure classification-based assessment of CASP3 predictions for the fold recognition targets

1999 • 80 citations

Ab initio protein structure prediction using a combined hierarchical approach

1999 • 70 citations

NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer

1999 • 66 citations

Ab initio protein structure prediction using a combined hierarchical approach

1999 • 56 citations

Folding nucleus: specific of multiple? insights from lattice models and experiments

1998 • 49 citations

A molecular dynamics simulation study of segment B1 of protein G

1997 • 42 citations

Fishing for folding nuclei in lattice models and proteins

1998 • 34 citations