Conservation of rapid two-state folding in mesophilic, thermophilic and hyperthermophilic cold shock proteins

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1990 • 15,514 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

How to measure and predict the molar absorption coefficient of a protein

1995 • 3,771 citations

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1957 • 2,481 citations

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1986 • 2,265 citations

Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl .alpha.-chymotrypsin using different denaturants

1988 • 1,568 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

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1990 • 1,133 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

How does a protein fold?

1994 • 947 citations

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

1991 • 882 citations

Thermotoga maritima sp. nov. represents a new genus of unique extremely thermophilic eubacteria growing up to 90�C

1986 • 762 citations

Folding and association of proteins

1987 • 697 citations

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1987 • 599 citations

Toward an outline of the topography of a realistic protein-folding funnel.

1995 • 510 citations

Transient folding intermediates characterized by protein engineering

1990 • 446 citations

The barriers in protein folding

1994 • 436 citations

PATHWAYS OF PROTEIN FOLDING

1993 • 435 citations

Universal nucleic acid-binding domain revealed by crystal structure of the B. subtilis major cold-shock protein

1993 • 352 citations

Evidence for a three-state model of protein folding from kinetic analysis of ubiquitin variants with altered core residues

1996 • 347 citations

Conserved residues and the mechanism of protein folding

1996 • 347 citations

Protein folding funnels: the nature of the transition state ensemble

1996 • 326 citations

Kinetic role of early intermediates in protein folding

1997 • 324 citations

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1995 • 315 citations

Kinetic traps in lysozyme folding.

1995 • 298 citations

Extremely rapid protein folding in the absence of intermediates

1995 • 282 citations

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1996 • 259 citations

Thermodynamic and Kinetic Analysis of the SH3 Domain of Spectrin Shows a Two-State Folding Transition

1994 • 252 citations

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1978 • 247 citations

Protein folding and stability: the pathway of folding of barnase

1993 • 242 citations

Characterization of cspB, a Bacillus subtilis inducible cold shock gene affecting cell viability at low temperatures

1992 • 238 citations

Folding and stability of a tryptophan-containing mutant of ubiquitin

1993 • 232 citations

Different folding transition states may result in the same native structure

1996 • 219 citations

Submillisecond folding of monomeric lambda repressor.

1995 • 218 citations

Structure in solution of the major cold-shock protein from Bacillus subtilis

1993 • 218 citations

The energy landscape of a fast-folding protein mapped by Ala→Gly Substitutions

1997 • 187 citations

Three-state model for lysozyme folding: triangular folding mechanism with an energetically trapped intermediate

1997 • 176 citations

Kinetics of unfolding and refolding of proteins

1973 • 173 citations

Kinetics of unfolding and refolding of proteins

1973 • 145 citations

Folding of a four-helix bundle: studies of acyl-coenzyme A binding protein

1995 • 144 citations

Structure of the hydrophobic core in the transition state for folding of chymotrypsin inhibitor 2: A critical test of the protein engineering method of analysis

1993 • 141 citations

Microsecond Protein Folding Through a Compact Transition State

1996 • 135 citations

Thermodynamic Properties of an Extremely Rapid Protein Folding Reaction

1996 • 128 citations

Movement of the position of the transition state in protein folding

1995 • 126 citations

Absence of a stable intermediate on the folding pathway of protein A

1997 • 120 citations

Kinetics of unfolding and refolding of proteins

1973 • 119 citations

P22 Arc Repressor: Transition State Properties Inferred from Mutational Effects on the Rates of Protein Unfolding and Refolding

1995 • 113 citations

Universality and diversity of the protein folding scenarios:a comprehensive analysis with the aid of a lattice model

1996 • 109 citations

Fast and One-step Folding of Closely and Distantly Related Homologous Proteins of a Four-helix Bundle Family

1996 • 105 citations

Role of Non-Native Aromatic and Hydrophobic Interactions in the Folding of Hen Egg White Lysozyme

1996 • 93 citations

Evidence for a Two-State Transition in the Folding Process of the Activation Domain of Human Procarboxypeptidase A2

1995 • 82 citations

Folding of the disulfide-bonded β-sheet protein tendamistat: rapid two-state folding without hydrophobic collapse 1 1Edited by A. R. Fersht

1997 • 61 citations

Non-native local interactions in protein folding and stability: introducing a helical tendency in the all β-sheet α-spectrin SH3 domain

1997 • 58 citations

Protein Folding: Matching Theory and Experiment

1998 • 54 citations

Overproduction, crystallization, and preliminary X‐ray diffraction studies of the major cold shock protein from Bacillus subtilis, CspB

1992 • 47 citations

Intermediates In The Folding Reactions Of Small Proteins

1990 • 35 citations

Pathways of Protein Folding

1993 • 17 citations