The regulation of the intracellular pH in cells from vertebrates

Intracellular pH.

1981 • 2,440 citations

Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiace and skeletal muscles.

1978 • 1,086 citations

Cytoplasmic pH and free Mg2+ in lymphocytes.

1982 • 1,047 citations

Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors.

1976 • 913 citations

Amiloride: a molecular probe of sodium transport in tissues and cells

1982 • 837 citations

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1983 • 721 citations

Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles

1982 • 681 citations

Metabolic regulation via intracellular pH

1984 • 674 citations

Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney

1976 • 665 citations

The sodium/hydrogen exchange system in cardiac cells: Its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH

1985 • 612 citations

Intracellular pH regulation in the renal proximal tubule of the salamander. Basolateral HCO3- transport.

1983 • 549 citations

A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH.

1984 • 544 citations

Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance

1979 • 479 citations

A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells

1985 • 456 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport.

1984 • 434 citations

Responses of lymphocytes to anisotonic media: volume-regulating behavior

1984 • 427 citations

The role of bicarbonate, chloride and sodium ions in the regulation of intracellular pH in snail neurones

1977 • 366 citations

Volume regulation by Amphiuma red blood cells. The membrane potential and its implications regarding the nature of the ion-flux pathways.

1980 • 359 citations

Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na+/H+ antiport.

1984 • 354 citations

Review Lecture: Experimental displacement of intracellular pH and the mechanism of its subsequent recovery.

1984 • 350 citations

Acidification of the cytosol inhibits endocytosis from coated pits.

1987 • 345 citations

Intracellular pH of snail neurones measured with a new pH‐sensitive glass micro‐electrode

1974 • 344 citations

Serum stimulates the Na+,K+ pump in quiescent fibroblasts by increasing Na+ entry.

1978 • 319 citations

Hydrogen ion currents and intracellular pH in depolarized voltage-clamped snail neurones

1982 • 316 citations

Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.

1984 • 305 citations

Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH

1987 • 302 citations

Rheogenic sodium-bicarbonate cotransport in the peritubular cell membrane of rat renal proximal tubule

1985 • 288 citations

Colocalization of Band 3 with Ankyrin and Spectrin at the Basal Membrane of Intercalated Cells in the Rat Kidney

1985 • 286 citations

Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.

1982 • 282 citations

Transport of H+ and of ionic weak acids and bases

1983 • 271 citations

Mechanism of basolateral membrane H+/OH-/HCO-3 transport in the rat proximal convoluted tubule. A sodium-coupled electrogenic process.

1985 • 266 citations

Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.

1985 • 254 citations

Cytoplasmic pH, a key determinant of growth factor‐induced DNA synthesis in quiescent fibroblasts

1985 • 247 citations

Na+/HCO3-co-transport in basolateral membrane vesicles isolated from rabbit renal cortex.

1986 • 237 citations

Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells.

1983 • 230 citations

Angiotensin II-stimulated Na+/H+ exchange in cultured vascular smooth muscle cells. Evidence for protein kinase C-dependent and -independent pathways.

1987 • 228 citations

The effect of carbon dioxide on the intracellular pH and buffering power of snail neurones.

1976 • 227 citations

Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.

1982 • 218 citations

Biochemical characterization of the amiloride-sensitive Na+/H+ antiport in Chinese hamster lung fibroblasts.

1983 • 217 citations

Two types of collecting duct mitochondria-rich (intercalated) cells: lectin and band 3 cytochemistry

1986 • 212 citations

Ca2+ ions can affect intracellular pH in mammalian cardiac muscle

1983 • 210 citations

Activation of Na+/H+ exchange in lymphocytes by osmotically induced volume changes and by cytoplasmic acidification.

1983 • 209 citations

Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system.

1984 • 204 citations

The role of the Na+/H+ exchange system in cardiac cells in relation to the control of the internal Na+ concentration. A molecular basis for the antagonistic effect of ouabain and amiloride on the heart.

1984 • 201 citations

The effect of calcium injection on the intracellular sodium and pH of snail neurones.

1977 • 200 citations

Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.

1984 • 185 citations

Micro‐electrode measurement of the intracellular pH and buffering power of mouse soleus muscle fibres.

1977 • 184 citations

Aldosterone activates Na+/H+ exchange and raises cytoplasmic pH in target cells of the amphibian kidney.

1987 • 184 citations

The mitogenic signaling pathway of fibroblast growth factor is not mediated through polyphosphoinositide hydrolysis and protein kinase C activation in hamster fibroblasts.

1986 • 178 citations

Stimulation of Na:H exchange by insulin

1981 • 177 citations

Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption.

1987 • 176 citations

Activation of sodium–proton exchange is a prerequisite for Ca2+ mobilization in human platelets

1987 • 176 citations

Role of a Na+-dependent Cl-/HCO3- exchange in regulation of intracellular pH in fibroblasts.

1985 • 175 citations

Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

1985 • 175 citations

Sodium fluxes in human fibroblasts: Effect of serum, Ca⁺², and amiloride

1981 • 173 citations

Serum, platelet-derived growth factor, vasopressin and phorbol esters increase intracellular pH in Swiss 3T3 cells

1983 • 170 citations

Ethylisopropyl-amiloride: A new and highly potent derivative of amiloride for the inhibition of the Na+H+ exchange system in various cell types

1983 • 168 citations

Stoichiometry and ion dependencies of the intracellular-pH-regulating mechanism in squid giant axons.

1983 • 167 citations

Intracellular pH Regulation in Epithelial Cells

1986 • 167 citations

Pertussis toxin inhibits thrombin-induced activation of phosphoinositide hydrolysis and Na+/H+ exchange in hamster fibroblasts.

1986 • 165 citations

The proton translocating ATPase responsible for urinary acidification.

1982 • 164 citations

Mechanism of osmotic activation of Na+/H+ exchange in rat thymic lymphocytes.

1985 • 160 citations

The regulation of cytoplasmic pH in human fibroblasts.

1984 • 157 citations

Intracellular pH modulates the generation of superoxide radicals by human neutrophils.

1985 • 156 citations

ATP-Driven H+ Pumping into Intracellular Organelles

1986 • 154 citations

Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs.

1986 • 153 citations

An electrogenic proton-translocating adenosine triphosphatase from bovine kidney medulla.

1984 • 153 citations

Regulation of intracellular pH in human neutrophils.

1985 • 152 citations

Platelet-derived growth factor stimulates Na+/H+ exchange and induces cytoplasmic alkalinization in NR6 cells.

1983 • 145 citations

Regulation of human neutrophil chemotaxis by intracellular pH.

1986 • 145 citations

Early agonist-mediated ionic events in cultured vascular smooth muscle cells. Calcium mobilization is associated with intracellular acidification.

1987 • 145 citations

Digital image processing of intracellular pH in gastric oxyntic and chief cells

1987 • 145 citations

Epidermal growth factor stimulates amiloride-sensitive 22Na+ uptake in A431 cells. Evidence for Na+/H+ exchange.

1983 • 142 citations

Glucocorticoids increase the Na+-H+ exchange and decrease the Na+ gradient-dependent phosphate-uptake systems in renal brush border membrane vesicles.

1982 • 135 citations

Chloride transport across the basolateral cell membrane of theNecturus proximal tubule: Dependence on bicarbonate and sodium

1983 • 129 citations

Interrelationship between growth factor-induced pH changes and intracellular Ca2+.

1987 • 128 citations

Lys-bradykinin stimulates Na+ influx and DNA synthesis in cultured human fibroblasts

1983 • 127 citations

DEFECTIVE JEJUNAL BRUSH-BORDER Na+/H+ EXCHANGE: A CAUSE OF CONGENITAL SECRETORY DIARRHOEA

1985 • 127 citations

Parallel adaptation of the rabbit renal cortical sodium/proton antiporter and sodium/bicarbonate cotransporter in metabolic acidosis and alkalosis.

1987 • 127 citations

Intracellular pH controls growth factor-induced ribosomal protein S6 phosphorylation and protein synthesis in the G0→G1 transition of fibroblasts

1986 • 126 citations

The amiloride-sensitive Na+/H+ exchange system in skeletal muscle cells in culture.

1982 • 124 citations

Mixed type inhibition of the renal Na+/H+ antiporter by Li+ and amiloride. Evidence for a modifier site.

1983 • 124 citations

A transient sodium‐hydrogen exchange system induced by catecholamines in erythrocytes of rainbow trout, Salmo gairdneri.

1984 • 123 citations

The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.

1983 • 123 citations

The mechanism of insulin stimulation of (Na+,K+)-ATPase transport activity in muscle.

1985 • 123 citations

Flow cytometric measurement of cytoplasmic pH: A critical evaluation of available fluorochromes

1986 • 122 citations

Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.

1984 • 121 citations

Depletion of cellular ATP inhibits Na+/H+ antiport in cultured human cells. Modulation of the regulatory effect of intracellular protons on the antiporter activity.

1986 • 119 citations

Regulation of cell pH by Ca+2-mediated exocytotic insertion of H+-ATPases.

1986 • 117 citations

Mechanisms of Gastric H⁺ and C1^- Transport

1980 • 117 citations

pH-regulated anion antiport in nucleated mammalian cells.

1986 • 117 citations

Cyclic AMP inhibits Na+/H+ exchange at the apical membrane of Necturus gallbladder epithelium.

1985 • 114 citations

Interleukin 2 induces a rapid increase in intracellular pH through activation of a Na+/H+ antiport. Cytoplasmic alkalinization is not required for lymphocyte proliferation.

1985 • 114 citations

Stimulation of Na+H+ antiport activity by epidermal growth factor and insulin occurs without activation of protein kinase C

1985 • 112 citations

Amiloride-sensitive Na+/H+ exchange in human neutrophils: Mechanism of activation by chemotactic factors

1984 • 111 citations

Chloride activity and its control in skeletal and cardiac muscle

1982 • 111 citations

Na+-dependent hexose transport in vesicles from cultured renal epithelial cell line

1982 • 109 citations

CO2-stimulated NaCl absorption in the mouse renal cortical thick ascending limb of Henle. Evidence for synchronous Na +/H+ and Cl-/HCO3- exchange in apical plasma membranes.

1982 • 107 citations

Specific modulation of the intracellular pH of rabbit neutrophils by chemotactic factors

1980 • 106 citations

Phorbol ester stimulation of Na influx and Na-K pump activity in swiss 3T3 cells

1981 • 106 citations

An investigation of chloride‐bicarbonate exchange in the sheep cardiac Purkinje fibre.

1986 • 105 citations

Apical Na+/H+ antiporter and glycolysis-dependent H+-ATPase regulate intracellular pH in the rabbit S3 proximal tubule.

1987 • 105 citations

Adaptation of Na+-H+ exchange in renal microvillus membrane vesicles. Role of dietary protein and uninephrectomy.

1984 • 104 citations

Thrombin activation of the Na+/H+ exchanger in vascular smooth muscle cells. Evidence for a kinase C-independent pathway which is Ca2+-dependent and pertussis toxin-sensitive.

1987 • 104 citations

Na+-H+ exchange activity in renal brush border membrane vesicles in response to metabolic acidosis: The role of glucocorticoids.

1984 • 104 citations

Angiotensin II effect on cytosolic pH in cultured rat vascular smooth muscle cells.

1987 • 103 citations

Molecular properties of amiloride action and of its Na+ transporting targets

1987 • 103 citations

Biochemical properties of the Na+/H+ exchange system in rat brain synaptosomes. Interdependence of internal and external pH control of the exchange activity.

1985 • 102 citations

Volume regulation by Necturus gallbladder: apical Na+-H+ and Cl(-)-HCO-3 exchange

1982 • 101 citations

Chemotactic factor-induced activation of Na+/H+ exchange in human neutrophils. II. Intracellular pH changes.

1985 • 101 citations

The Na+/H+ antiport is activated by serum and phorbol esters in proliferating myoblasts but not in differentiated myotubes. Properties of the activation process.

1985 • 100 citations

pH regulation in barnacle muscle fibers: dependence on extracellular sodium and bicarbonate

1981 • 100 citations

Volume-responsive sodium movements in dog red blood cells

1983 • 100 citations

Polypeptides immunologically related to band 3 are present in nucleated somatic cells.

1983 • 98 citations

Evidence for a role of calmodulin in serum stimulation of Na+ influx in human fibroblasts.

1982 • 96 citations

Thyroid hormones increase Na+-H+ exchange activity in renal brush border membranes.

1985 • 94 citations

Sodium-hydrogen exchange and glucose transport in renal microvillus membrane vesicles from rats with diabetes mellitus.

1986 • 93 citations

Cytoplasmic pH regulation in normal and abnormal neutrophils. Role of superoxide generation and Na+/H+ exchange.

1986 • 93 citations

Influence of sodium‐hydrogen exchange on intracellular pH, sodium and tension in sheep cardiac Purkinje fibres.

1987 • 93 citations

Optical measurements of intracellular pH in single LLC-PK1 cells: demonstration of Cl-HCO3 exchange.

1986 • 93 citations

Mitogen‐independent activation of Na⁺/H⁺ exchange in human epidermoid carcinoma A431 cells: Regulation by medium osmolarity

1985 • 92 citations

Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger

1988 • 91 citations

Proton gradients in renal cortex brush-border membrane vesicles. Demonstration of a rheogenic proton flux with acridine orange.

1981 • 89 citations

Proton pathways in rat renal brush-border and basolateral membranes

1983 • 88 citations

Electrogenic sodium/bicarbonate cotransport in rabbit renal cortical basolateral membrane vesicles.

1986 • 88 citations

The role of the Na+/H+ exchange system in the regulation of the internal pH in cultured cardiac cells

1985 • 87 citations

Intracellular pH-regulating mechanism of the squid axon. Relation between the external Na+ and HCO-3 dependences.

1985 • 84 citations

Intracellular pH in human and experimental hypertension.

1987 • 83 citations

Volume-responsive sodium and proton movements in dog red blood cells.

1984 • 83 citations

Insulin-induced cytoplasmic alkalinization and glucose transport in muscle cells

1986 • 81 citations

A bicarbonate-dependent process inhibitable by disulfonic stilbenes and a Na+/H+ exchange mediate 22Na+ uptake into cultured bovine corneal endothelium.

1985 • 79 citations

Tumor promoter phorbol 12-myristate 13-acetate inhibits mitogen-stimulated Na+/H+ exchange in human epidermoid carcinoma A431 cells.

1984 • 78 citations

Protein kinase C activates the renal apical membrane Na+/H+ exchanger

1986 • 78 citations

22Na+ fluxes in thymic lymphocytes. II. Amiloride-sensitive Na+/H+ exchange pathway; reversibility of transport and asymmetry of the modifier site.

1984 • 78 citations

Coupling between phosphoinositide breakdown and early mitogenic events in fibroblasts. Studies with fluoroaluminate, vanadate, and pertussis toxin.

1987 • 77 citations

Stimulation of the T3-T cell receptor-associated Ca2+ influx enhances the activity of the Na+/H+ exchanger in a leukemic human T cell line.

1985 • 75 citations

The Na⁺/H⁺ exchange system in glial cell lines

1986 • 74 citations

Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.

1984 • 74 citations

Intracellular pH and Na fluxes in barnacle muscle with evidence for reversal of the ionic mechanism of intracellular pH regulation.

1983 • 74 citations

Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes.

1987 • 73 citations

Protein phosphorylation during activation of Na+/H+ exchange by phorbol esters and by osmotic shrinking. Possible relation to cell pH and volume regulation.

1986 • 73 citations

HCO3- transport in basolateral membrane vesicles isolated from rat renal cortex.

1987 • 73 citations

Dissociation of cellular responses to epidermal growth factor using anti-receptor monoclonal antibodies.

1986 • 72 citations

Activation of Na+/H+ exchange in cultured fibroblasts: synergism and antagonism between phorbol ester, Ca2+ ionophore, and growth factors.

1985 • 71 citations

Effects of changes of intracellular pH on contraction in sheep cardiac Purkinje fibers.

1987 • 71 citations

Modification of the internal pH sensitivity of the Na+/H+ antiporter by parathyroid hormone in a cultured renal cell line.

1987 • 71 citations

Effect of the intracellular Ca+2 antagonist TMB-8 on serum-stimulated Na+ influx in human fibroblasts

1982 • 70 citations

Vasopressin rapidly stimulates NA entry and NA‐K pump activity in quiescent cultures of mouse 3T3 cells

1980 • 69 citations

The Na+-dependent regulation of the internal pH in chick skeletal muscle cells. The role of the Na+/H+ exchange system and its dependence on internal pH.

1984 • 67 citations

Kidney epithelial cells of monkey origin (BSC-1) express a sodium bicarbonate cotransport. Characterization by 22Na+ flux measurements.

1985 • 67 citations

Volume‐regulating behavior of human platelets

1987 • 67 citations

Isolation and properties of fibroblast mutants overexpressing an altered Na+/H+ antiporter.

1986 • 66 citations

Alpha 2-adrenergic receptors accelerate Na+/H+ exchange in neuroblastoma X glioma cells.

1987 • 66 citations

Na+-H+ exchange in isolated renal brush-border membrane vesicles in response to metabolic acidosis. Kinetic effects.

1984 • 65 citations

Na+-H+ exchange and Na+ entry across the apical membrane of Necturus gallbladder.

1984 • 65 citations

The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na+/H+ antiport, Na+-HCO3(-)-(NaCO3-) symport, and Cl-/HCO3- exchange.

1986 • 64 citations

Lymphocyte membrane sodium-proton exchange in spontaneously hypertensive rats.

1987 • 62 citations

Multiple tissue-specific sites of transcriptional initiation of the mouse anion antiport gene in erythroid and renal cells.

1987 • 61 citations

Agents for the treatment of brain edema. 2. [(2,3,9,9a-Tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]alkanoic acids and some of their analogs

1986 • 61 citations

The intracellular pH of frog skeletal muscle: its regulation in hypertonic solutions.

1983 • 59 citations

Chemotactic factor-induced activation of Na+/H+ exchange in human neutrophils. I. Sodium fluxes.

1985 • 56 citations

Osmotic activation of the Na+H+ antiport in protein kinase C-depleted lymphocytes

1986 • 56 citations

Intracellular pH in human fibroblasts: effect of mitogens, A23187, and phospholipase activation

1985 • 56 citations

Bicarbonate/chloride antiport in vero cells: I. Evidence for both sodium‐linked and sodium‐independent exchange

1987 • 56 citations

The significance of the relative effects of loop diuretics and anti-brain edema agents on the Na+, K+, Cl− cotransport system and the Cl−/NaCO 3 − anion exchanger

1986 • 55 citations

Differentiation of human promyelocytic HL 60 cells by retinoic acid is accompanied by an increase in the intracellular pH. The role of the Na+/H+ exchange system.

1987 • 55 citations

Vanadate stimulates Na+H+ exchange activity in A431 cells

1984 • 54 citations

Na+/H+ exchange in Ehrlich ascites tumor cells. Regulation by extracellular ATP and 12-O-tetradecanoylphorbol 13-acetate.

1986 • 53 citations

Intracellular pH in sheep Purkinje fibres and ferret papillary muscles during hypoxia and recovery.

1987 • 53 citations

Analysis of Cl- -HCO3(-) exchange during recovery from intracellular acidosis in cardiac Purkinje strands

1984 • 52 citations

[3H]Ethylpropylamiloride, a ligand to analyze the properties of the Na+/H+ exchange system in the membranes of normal and hypertrophied kidneys.

1985 • 51 citations

Characteristics of an amiloride‐sensitive sodium entry pathway in cultured rodent glial and neuroblastoma cells

1983 • 50 citations

Platelet-derived growth factor stimulates Na+ influx in vascular smooth muscle cells

1984 • 50 citations

Sodium fluxes in human fibroblasts: Kinetics of serum‐dependent and serum‐independent pathways

1981 • 49 citations

Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells.

1986 • 49 citations

Multiplication-stimulating activity-induced alkalinization of canine renal proximal tubular cells.

1986 • 49 citations

Thrombin stimulates Na⁺‐H⁺ exchange across the human platelet plasma membrane

1984 • 48 citations

Mechanism of activation of lymphocyte Na+/H+ exchange by concanavalin A. A calcium- and protein kinase C-independent pathway.

1987 • 48 citations

Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines

1987 • 48 citations

Electrical effects of potassium and bicarbonate on proximal tubule cells ofNecturus

1984 • 46 citations

Purification and subunit structure of the [3H]phenamil receptor associated with the renal apical Na+ channel.

1987 • 46 citations

Ionic responses rapidly elicited by porcine platelet-derived growth factor in Swiss 3T3 cells.

1984 • 46 citations

Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids

1982 • 45 citations

Relationship between pH, sodium, and shape changes in chemotactic‐factor‐stimulated human neutrophils

1987 • 44 citations

Effect of catecholamines on Na/H exchange in vascular smooth muscle cells.

1986 • 43 citations

The Na+/H+ exchanger is constitutively activated in P19 embryonal carcinoma cells, but not in a differentiated derivative. Responsiveness to growth factors and other stimuli.

1987 • 41 citations

Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells.

1987 • 41 citations

Activation of the Na+/H+ antiport is not required for lectin-induced proliferation of human T lymphocytes.

1986 • 41 citations

Bicarbonate/chloride antiport in vero cells: II. Mechanisms for bicarbonate‐dependent regulation of intracellular pH

1987 • 38 citations

Interaction of guanidinium and guanidinium derivatives with the Na+/H+ exchange system

1986 • 38 citations

Kinetic properties of the sodium bicarbonate (carbonate) symport in monkey kidney epithelial cells (BSC-1). Interactions between Na+, HCO-3, and pH.

1986 • 37 citations

Regulation of intracellular sodium and pH by the electrogenic H+ pump in frog skin

1986 • 35 citations

Activation of Amiloride‐Sensitive Sodium Transport in C6 Glioma Cells

1984 • 34 citations

[3H]Phenamil, a radiolabelled diuretic for the analysis of the amiloride-sensitive Na+ channels in kidney membranes

1986 • 34 citations

Cytoplasmic pH regulation in activated human neutrophils: Effects of adenosine and pertussis toxin on Na+H+ exchange and metabolic acidification

1986 • 33 citations

Identification of Amiloride-Sensitive Na⁺/H⁺Exchange in Rat NB2 Node Lymphoma Cells. Stimulation by 12-0-Tetradecanoyl-Phorbol-13-Acetate*

1987 • 32 citations

Effect of insulin on intracellular pH in frog skeletal muscle fibers

1985 • 32 citations

H+ transport and the regulation of intracellular pH in ehrlich ascites tumor cells

1984 • 31 citations

Kinetic studies on the stimulation of Na+−H+ exchange activity in renal brush border membranes isolated from thyroid hormone-treated rats

1986 • 30 citations

The activity of the Na⁺/H⁺ antiporter in cultured cardiac cells is dependent on the culture conditions used

1986 • 29 citations

Sodium-hydrogen exchange system in LLC-PK1 epithelium

1987 • 29 citations

Altered Ca fluxes and contractile state during pH changes in cultured heart cells

1987 • 28 citations

Cyclic AMP inhibits Cl-/HCO3- exchange at the apical membrane of Necturus gallbladder epithelium.

1987 • 28 citations

Properties of the Na+-dependent Cl-/HCO-3 exchange system in U937 human leukemic cells

1987 • 28 citations

Use of the pH sensitive fluorescence probe pyranine to monitor internal pH changes in Escherichia coli membrane vesicles

1984 • 27 citations

Thyrotropin-releasing hormone activates Na+/H+ exchange in rat pituitary cells

1987 • 26 citations

Role of the Na+/H+ antiport in the regulation of the internal pH of Ehrlich ascites tumor cells in culture

1986 • 26 citations

Amiloride-Sensitive Na⁺/H⁺Exchange in Rat NB2 Node Lymphoma Cells. Stimulation by Prolactin and Other Mitogens*

1987 • 26 citations

The intracellular pH of frog skeletal muscle: its regulation in isotonic solutions.

1983 • 25 citations

Membrane potential and sodium flux in neuroblastoma X glioma hybrid cells: Effects of amiloride and serum

1982 • 23 citations

Role of Ca2+ in serum-stimulated Na+ influx in normal and transformed cells

1985 • 23 citations

The amiloride sensitive Na⁺/H⁺ antiport in guinea pig pancreatic acini

1985 • 21 citations

Control of cytoplasmic pH by Na⁺/H⁺ exchange in rat peritoneal macrophages activated with phorbol ester

1987 • 21 citations

Stimulation of monovalent ion fluxes and DNA synthesis in 3T3 cells by melittin and vasopressin is not mediated by phospholipid deacylation

1980 • 16 citations

Na⁺ for H⁺ exchange in rabbit erythrocytes

1987 • 15 citations

Stimulation by serum of the Na⁺/H⁺ antiporter in quiescent pig kidney epithelial (LLC‐PK₁) cells and role of the antiporter in the reinitiation of DNA synthesis

1987 • 14 citations

Desensitization of the serum effect on Na⁺ influx in cultured human fibroblasts

1984 • 12 citations

Intracellular pH measurements using the fluorescence of 9‐aminoacridine

1984 • 12 citations

Energetics and mechanics of frog skeletal muscle in hypotonic solution

1986 • 11 citations

Proton permeability of the plasma membrane of rat cortical synaptosomes

1987 • 10 citations

Effect of heparin-binding growth factors on monovalent cation transport in Balb/C 3T3 cells

1987 • 9 citations

Flow cytometric analysis of intracellular pH in 3T3 cells

1987 • 9 citations

Modification of ultraviolet radiation effects on the membrane of myelinated nerve fibers by sulfhydryl compounds

1984 • 5 citations