Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Amiloride: a molecular probe of sodium transport in tissues and cells

1982 • 837 citations

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1983 • 721 citations

Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney

1976 • 665 citations

An investigation of the ionic mechanism of intracellular pH regulation in mouse soleus muscle fibres

1977 • 399 citations

Increased sodium ion influx is necessary to initiate rat hepatocyte proliferation

1979 • 376 citations

Volume regulation by Amphiuma red blood cells. The membrane potential and its implications regarding the nature of the ion-flux pathways.

1980 • 359 citations

Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.

1982 • 282 citations

Transport of H+ and of ionic weak acids and bases

1983 • 271 citations

Growth factor activation of an amiloride-sensitive Na+/H+ exchange system in quiescent fibroblasts: coupling to ribosomal protein S6 phosphorylation.

1982 • 240 citations

Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.

1982 • 218 citations

Biochemical characterization of the amiloride-sensitive Na+/H+ antiport in Chinese hamster lung fibroblasts.

1983 • 217 citations

Stimulation of Na:H exchange by insulin

1981 • 177 citations

MONOVALENT ION FLUXES AND THE CONTROL OF CELL PROLIFERATION IN CULTURED FIBROBLASTS

1980 • 176 citations

Ions, Cell Proliferation, and Cancer

1982 • 170 citations

Sodium/proton exchange in mouse neuroblastoma cells.

1981 • 166 citations

Epidermal growth factor stimulates amiloride-sensitive 22Na+ uptake in A431 cells. Evidence for Na+/H+ exchange.

1983 • 142 citations

Evidence for Na+/H+ antiport in cultured dog kidney cells (MDCK).

1981 • 132 citations

Lys-bradykinin stimulates Na+ influx and DNA synthesis in cultured human fibroblasts

1983 • 127 citations

Stimulation of Na influx, Na-K pump activity and DNA synthesis in quiescent cultured cells

1981 • 126 citations

The amiloride-sensitive Na+/H+ exchange system in skeletal muscle cells in culture.

1982 • 124 citations

The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.

1983 • 123 citations

Amiloride blocks cell-free protein synthesis at levels attained inside cultured rat hepatocytes

1982 • 77 citations

Importance of guanidinium groups of blocking sodium channels in epithelia.

1976 • 70 citations

Pyrazine Diuretics. I. N-Amidino-3-amino-6-halopyrazinecarboxamides

1965 • 58 citations

A cardiac tetrodotoxin-binding component: biochemical identification, characterization, and properties

1981 • 52 citations

Relationship between increased aerobic glycolysis and DNA synthesis initiation studied using glycolytic mutant fibroblasts

1980 • 46 citations

Emergence of hamster fibroblast tumors in nude mice—evidence for in vivo selection leading to loss of growth factor requirement

1981 • 39 citations

Ionic landmarks along the mitogenic route

1979 • 35 citations

Analysis of growth factor “relaxation” in chinese hamster lung fibroblasts required for tumoral expression

1983 • 33 citations

Demonstration of a late amiloride‐sensitive event as a necessary step in initiation of DNA synthesis by thrombin

1983 • 32 citations

Inhibitory and stimulatory effects of amiloride analogues on sodium transport in frog skin

1979 • 27 citations

Pyrazine diuretics. VII. N-Amidino-3-substituted pyrazinecarboxamides

1969 • 14 citations