Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Human epidermal growth factor and the proliferation of human fibroblasts

1976 • 403 citations

Epidermal Growth Factor: Effects of Androgens and Adrenergic Agents

1974 • 393 citations

Increased sodium ion influx is necessary to initiate rat hepatocyte proliferation

1979 • 376 citations

Pyrazine Diuretics. II. N-Amidino-3-amino-5-substituted 6-Halopyrazinecarboxamides

1967 • 323 citations

Continuous protein synthesis is required to maintain the probability of entry into S phase

1977 • 308 citations

Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.

1984 • 305 citations

Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.

1982 • 282 citations

Rapid ionic events and the initiation of growth in serum-stimulated neuroblastoma cells

1981 • 242 citations

Growth factor activation of an amiloride-sensitive Na+/H+ exchange system in quiescent fibroblasts: coupling to ribosomal protein S6 phosphorylation.

1982 • 240 citations

Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells.

1983 • 230 citations

Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.

1982 • 218 citations

Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts.

1982 • 185 citations

Amiloride Directly Inhibits the Na,K-ATPase Activity of Rabbit Kidney Proximal Tubules

1983 • 172 citations

Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors

1978 • 162 citations

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.

1983 • 150 citations

Plasma Concentrations of Immunoreactive Human Epidermal Growth Factor (Urogastrone) in Man*

1980 • 127 citations

Lys-bradykinin stimulates Na+ influx and DNA synthesis in cultured human fibroblasts

1983 • 127 citations

The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.

1983 • 123 citations

Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.

1984 • 121 citations

Two forms of murine epidermal growth factor: rapid separation by using reverse-phase HPLC.

1982 • 78 citations

Amiloride blocks cell-free protein synthesis at levels attained inside cultured rat hepatocytes

1982 • 77 citations

Persistence of the mitogenic response to platelet-derived growth factor (competence) does not reflect a long-term interaction between the growth factor and the target cell.

1983 • 70 citations

Diuretics: Chemistry, Pharmacology, and Medicine

1984 • 56 citations

Inhibition of mouse mastocytoma protein kinases by amiloride

1982 • 44 citations

Demonstration of a late amiloride‐sensitive event as a necessary step in initiation of DNA synthesis by thrombin

1983 • 32 citations

Diuretics--chemistry, pharmacology, and medicine

1983 • 12 citations