Distinct recognition by two subsets of T cells of an MHC class II-peptide complex

IMGT, the international ImMunoGeneTics database

2000 • 877 citations

Structure of the p53 Tumor Suppressor Bound to the Ankyrin and SH3 Domains of 53BP2

1996 • 569 citations

The Crystal Structure of a T Cell Receptor in Complex with Peptide and MHC Class II

1999 • 400 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

Structures of an MHC Class II Molecule with Covalently Bound Single Peptides

1996 • 369 citations

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1987 • 367 citations

IMGT, the international ImMunoGeneTics database

1999 • 347 citations

Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

1987 • 297 citations

Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1

2000 • 271 citations

Defective Antigen Processing in GILT-Free Mice

2001 • 260 citations

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

1991 • 250 citations

Crystal Structure of I-Ak in Complex with a Dominant Epitope of Lysozyme

1998 • 245 citations

Crystal Structures of Two I-Ad–Peptide Complexes Reveal That High Affinity Can Be Achieved without Large Anchor Residues

1998 • 236 citations

IMGT, the international ImMunoGeneTics database

2001 • 220 citations

Cytokine-regulated proteases in autoimmune diseases

1994 • 214 citations

Structural Basis of Peptide Binding and Presentation by the Type I Diabetes-Associated MHC Class II Molecule of NOD Mice

2000 • 197 citations

Cytokines Regulate Proteolysis in Major Histocompatibility Complex Class II–Dependent Antigen Presentation by Dendritic Cells

2001 • 186 citations

Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103).

1994 • 185 citations

Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas.

1984 • 175 citations

Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak.

1992 • 174 citations

T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage

1997 • 174 citations

Characterization and Quantitation of Peptide–MHC Complexes Produced from Hen Egg Lysozyme Using a Monoclonal Antibody

1997 • 169 citations

Degenerate recognition of a dissimilar antigenic peptide by myelin basic protein-reactive T cells. Implications for thymic education and autoimmunity.

1993 • 149 citations

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation.

1992 • 125 citations

Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing.

1996 • 120 citations

Distinct antigen MHC class II complexes generated by separate processing pathways.

1996 • 115 citations

In vivopriming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen

1998 • 108 citations

Quantitative Analysis of the T Cell Repertoire that Escapes Negative Selection

1999 • 103 citations

Identification of two distinct properties of class II major histocompatibility complex-associated peptides.

1993 • 101 citations

A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak.

1996 • 84 citations

IMGT,international ImMunoGeneTics(国際免疫遺伝学)データベース

2000 • 81 citations

Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules

1997 • 79 citations

Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA DM genes.

1994 • 78 citations

Minimum structural requirements for peptide presentation by major histocompatibility complex class II molecules: implications in induction of autoimmunity.

1994 • 70 citations

Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity.

1995 • 69 citations

AMycobacterium leprae-Specific Human T Cell Epitope Cross-Reactive with an HLA-DR2 Peptide

1988 • 67 citations

Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens.

1987 • 65 citations

Altered I-A protein-mediated transmembrane signaling in B cells that express truncated I-Ak protein.

1989 • 61 citations

Quantitation of Lysozyme Peptides Bound to Class II MHC Molecules Indicates Very Large Differences in Levels of Presentation

2001 • 45 citations

Mechanisms and consequences of peptide selection by the I‐A^k class II molecule

1999 • 42 citations

Deamidation of Asparagine in a Major Histocompatibility Complex–Bound Peptide Affects T Cell Recognition but Does Not Explain Type B Reactivity

2001 • 26 citations

Biased T cell receptor usage by Ld-restricted, tum- peptide-specific cytotoxic T lymphocyte clones.

1993 • 25 citations

Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-A^kclass II molecules

2000 • 21 citations

Effect of HLA-DM transfection on hen egg lysozyme presentation by T2.Ak cells.

1996 • 16 citations