Crystal Structure of I-Ak in Complex with a Dominant Epitope of Lysozyme

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

The Relation Between Major Histocompatibility Complex (MHC) Restriction and the Capacity of Ia to Bind Immunogenic Peptides

1987 • 696 citations

The molecular surface package

1993 • 590 citations

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

1995 • 583 citations

Ribbon models of macromolecules

1987 • 519 citations

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.

1987 • 402 citations

Structures of an MHC Class II Molecule with Covalently Bound Single Peptides

1996 • 369 citations

X-Ray Crystal Structure of HLA-DR4 (DRA*0101, DRB1*0401) Complexed with a Peptide from Human Collagen II

1997 • 357 citations

Production of soluble MHC class II proteins with covalently bound single peptides

1994 • 302 citations

Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

1987 • 297 citations

Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas.

1984 • 272 citations

Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.

1996 • 247 citations

The beta bulge: a common small unit of nonrepetitive protein structure.

1978 • 237 citations

Mechanisms influencing the immunodominance of T cell determinants.

1988 • 227 citations

(His)Cε-H···O=C< Hydrogen Bond in the Active Sites of Serine Hydrolases

1994 • 215 citations

Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103).

1994 • 185 citations

The Specificity and Orientation of a TCR to its Peptide–MHC Class II Ligands

1996 • 177 citations

T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage

1997 • 174 citations

Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak.

1992 • 174 citations

Characterization and Quantitation of Peptide–MHC Complexes Produced from Hen Egg Lysozyme Using a Monoclonal Antibody

1997 • 169 citations

Comparison of peptides bound to spleen and thymus class II.

1993 • 168 citations

An Altered Position of the α2 Helix of MHC Class I Is Revealed by the Crystal Structure of HLA-B*3501

1996 • 160 citations

Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

1991 • 144 citations

Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH.

1991 • 143 citations

Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing.

1996 • 120 citations

How amino-acid insertions are allowed in an α-helix of T4 lysozyme

1993 • 101 citations

A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak.

1996 • 84 citations

pH dependence and exchange of high and low responder peptides binding to a class II MHC molecule.

1992 • 78 citations

Predominant role of amino-terminal sequences in dictating efficiency of class II major histocompatibility complex alpha beta dimer expression.

1987 • 57 citations

Appreciating the Complexity of MHC Class II Peptide Binding: Lysozyme Peptide and I‐A^k

1996 • 46 citations

Major histocompatibility complex gene organization in the mole rat Spalax ehrenbergi: evidence for transfer of function between class II genes.

1987 • 41 citations

Evaluation of the functional equivalence of major histocompatibility complex class II A and E complexes.

1992 • 31 citations

Class II Mhc Genes in Rodent Evolution

1990 • 22 citations

Amino acid residues on the I-Ak alpha-chain required for the binding and stability of two antigenic peptides.

1996 • 20 citations

Phospholipases that degrade the glycosyl-phosphatidylinositol anchor of membrane proteins

1992 • 12 citations

Expression and function of mixed isotype MHC class II molecules in normal mice.

1993 • 11 citations

High frequency ofH-2E 0 alleles among wild mice

1989 • 9 citations