Defective Antigen Processing in GILT-Free Mice

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Defective T Cell Differentiation in the Absence of Jnk1

1998 • 590 citations

Developmental Control of Endocytosis in Dendritic Cells by Cdc42

2000 • 440 citations

Enzymatic reduction of disulfide bonds in lysosomes: Characterization of a Gamma-interferon-inducible lysosomal thiol reductase (GILT)

2000 • 418 citations

JNK is required for effector T-cell function but not for T-cell activation

2000 • 322 citations

Reduction of disulfide bonds within lysosomes is a key step in antigen processing.

1991 • 245 citations

Gamma-Interferon-inducibleLysosomal Thiol Reductase (GILT)

2000 • 188 citations

Antigen conformation determines processing requirements for T-cell activation.

1984 • 181 citations

Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant.

1991 • 95 citations

Acidification and disulfide reduction can be sufficient to allow intact proteins to bind class II MHC.

1993 • 79 citations

The folding pathway of reduced lysozyme.

1976 • 76 citations

Large Protein Fragments as Substrates for Endocytic Antigen Capture by MHC Class II Molecules

1998 • 73 citations

Disulphide reduction in lysosomes. The role of cysteine

1986 • 67 citations

Depression of T-cell Epitope Generation by Stabilizing Hen Lysozyme

1997 • 57 citations

Conformational studies on modified proteins and peptides. VI. Conformation and immunochemistry of methylated and carboxymethylated derivatives of lysozyme

1973 • 41 citations

Processing and Reactivity of T Cell Epitopes Containing Two Cysteine Residues from Hen Egg-White Lysozyme (HEL74–90)

2000 • 27 citations

Propensities for the formation of individual disulfide bonds in hen lysozyme and the size and stability of disulfide‐associated submolecular structures

2000 • 25 citations

The expressed T cell repertoire is hierarchical: the precise focus of lysozyme-specific T cell clones is dependent upon the structure of the immunogen.

1984 • 19 citations