Brain-derived neurotrophic factor prevents neuronal death and glial activation after global ischemia in the rat

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

A new model of bilateral hemispheric ischemia in the unanesthetized rat.

1979 • 1,934 citations

Regulation of biosynthesis of nitric oxide.

1994 • 1,698 citations

Bright and dark sides of nitric oxide in ischemic brain injury

1997 • 1,043 citations

Cytotoxicity of microglia

1993 • 1,042 citations

Calcium: still center-stage in hypoxic-ischemic neuronal death

1995 • 921 citations

Effect of Ischemia on the In Vivo Release of Striatal Dopamine, Glutamate, and γ‐Aminobutyric Acid Studied by Intracerebral Microdialysis

1988 • 704 citations

Neurotrophins and brain insults

1994 • 564 citations

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.

1992 • 521 citations

Inducible Nitric Oxide Synthase Gene Expression in Brain following Cerebral Ischemia

1995 • 479 citations

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

1994 • 402 citations

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

1993 • 344 citations

The Two Patterns of Reactive Astrocytosis in Postischemic Rat Brain

1990 • 340 citations

Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia

1994 • 327 citations

Brain-Derived Neurotrophic Factor Protects against Ischemic Cell Damage in Rat Hippocampus

1994 • 326 citations

Intraventricular Brain-Derived Neurotrophic Factor Reduces Infarct Size after Focal Cerebral Ischemia in Rats

1997 • 326 citations

Endogenous Neuroprotection Factors and Traumatic Brain Injury: Mechanisms of Action and Implications for Therapy

1994 • 308 citations

Immunocytochemical Study of an Early Microglial Activation in Ischemia

1992 • 301 citations

Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS

1994 • 301 citations

Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain

1991 • 295 citations

Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of the p75 neurotrophin receptor

1998 • 283 citations

Calcium: still center-stage in hypoxic-ischemic neuronal death

1995 • 280 citations

BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones

1993 • 197 citations

Immunohistochemical study of glial reaction and serum-protein extravasation in relation to neuronal damage in rat hippocampus after ischemia

1990 • 185 citations

Inflammatory glia mediate delayed neuronal damage after ischemia in the central nervous system.

1993 • 155 citations

Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy

1997 • 144 citations

Progressive expression of immunomolecules on microglial cells in rat dorsal hippocampus following transient forebrain ischemia

1992 • 139 citations

Ischemia‐Induced Translocation of Ca²⁺/Calmodulin‐Dependent Protein Kinase II: Potential Role in Neuronal Damage

1992 • 134 citations

The Role of Brain-derived Neurotrophic Factor in Transient Forebrain Ischemia in the Rat Brain

1994 • 115 citations

Neurotrophins Protect Cultured Cerebellar Granule Neurons against the Early Phase of Cell Death by a TwoComponent Mechanism

1997 • 108 citations

Ischemia-Induced Neuronal Damage: A Role for Calcium/Calmodulin-Dependent Protein Kinase II

1996 • 102 citations

Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons

1995 • 100 citations

Brain-derived Neurotrophic Factor Increases Ca2+/Calmodulin-dependent Protein Kinase 2 Activity in Hippocampus

1997 • 62 citations

REVIEW ■ : Activation of Microglia: A Dangerous Interlude in Immune Function in the Brain

1996 • 51 citations

Calcium/calmodulin-dependent protein kinase II activity in focal ischemia with reperfusion in rats.

1994 • 46 citations

Effect of Cerebral Ischemia on Calcium/Calmodulin-Dependent Protein Kinase II Activity and Phosphorylation

1995 • 32 citations