Intraventricular Brain-Derived Neurotrophic Factor Reduces Infarct Size after Focal Cerebral Ischemia in Rats

Reversible middle cerebral artery occlusion without craniectomy in rats.

1989 • 6,875 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

Viability thresholds and the penumbra of focal ischemia

1994 • 1,358 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

1992 • 712 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.

1992 • 521 citations

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

1989 • 492 citations

Brain-derived neurotrophic factor prevents neuronal death in vivo

1988 • 490 citations

Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.

1993 • 484 citations

Temporal Profile of in situ DNA Fragmentation after Transient Middle Cerebral Artery Occlusion in the Rat

1995 • 477 citations

Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats.

1992 • 467 citations

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

1991 • 462 citations

Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death

1992 • 458 citations

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

1989 • 405 citations

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

1994 • 402 citations

Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration

1993 • 396 citations

Potentiated Necrosis of Cultured Cortical Neurons by Neurotrophins

1995 • 360 citations

Function and evolution in the NGF family and its receptors

1992 • 338 citations

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

1993 • 333 citations

Brain-Derived Neurotrophic Factor Protects against Ischemic Cell Damage in Rat Hippocampus

1994 • 326 citations

Characteristics of BDNF-induced weight loss

1995 • 313 citations

Diffusion‐weighted magnetic resonance imaging

1992 • 302 citations

Brain‐derived Neurotrophic Factor is a Survival Factor for Cultured Rat Cerebellar Granule Neurons and Protects them Against Glutamate‐induced Neurotoxicity

1993 • 287 citations

Induction of DNA Fragmentation After 10 to 120 Minutes of Focal Cerebral Ischemia in Rats

1995 • 276 citations

Regulation of Brain-Derived Neurotrophic Factor Gene Expression after Transient Middle Cerebral Artery Occlusion with and without Brain Damage

1995 • 248 citations

Distribution of Intracerebral Ventricularly Administered Neurotrophins in Rat Brain and Its Correlation with Trk Receptor Expression

1994 • 213 citations

Middle Cerebral Artery Occlusion in Rats

1992 • 198 citations

Delayed Treatment with Intravenous Basic Fibroblast Growth Factor Reduces Infarct Size following Permanent Focal Cerebral Ischemia in Rats

1995 • 180 citations

BDNF AND NGF TREATMENT IN LESIONED RATS

1992 • 156 citations

Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth.

1986 • 154 citations

Effects of Brain-derived Neurotrophic Factor on 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in Monkeys

1995 • 138 citations

The Role of Brain-derived Neurotrophic Factor in Transient Forebrain Ischemia in the Rat Brain

1994 • 115 citations

The effects of prolonged treatment with citicoline in temporary experimental focal ischemia

1996 • 111 citations

Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat

1994 • 104 citations

Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons

1995 • 100 citations

Pharmacokinetics of Intrathecally Applied BDNF and Effects on Spinal Motoneurons

1996 • 80 citations

Basic Fibroblast Growth Factor Dilates Rat Pial Arterioles

1994 • 78 citations

Basic Fibroblast Growth Factor Increases Regional Cerebral Blood Flow and Reduces Infarct Size After Experimental Ischemia in a Rat Model

1995 • 71 citations

Expression of immediate early gene and growth factor mRNAs in a focal cerebral ischemia model in the rat.

1993 • 63 citations

BDNF‐activated Sianal Transduction in Rat Cortical Glial Cells

1995 • 62 citations

Brain-derived neurotrophic factor pretreatment exerts a partially protective effect against glutamate-induced neurotoxicity in cultured rat cortical neurons

1993 • 62 citations

Calcium and glutamate-induced cortical neuronal death.

1993 • 59 citations

BDNF makes cultured dentate granule cells more resistant to hypoglycaemic damage

1994 • 57 citations

Alterations of a 200 kDa Neurofilament in the Rat Hippocampus after Forebrain Ischemia

1993 • 54 citations

Molecular and Cellular Approaches to the Treatment of Neurological Disease

1994 • 34 citations

Effect of Nerve Growth Factor on Glucose Utilization and Nucleotide Content of Pheochromocytoma Cells (Clone PC12)

1986 • 28 citations

Effect of nerve growth factor on delayed neuronal death and microtubule-associated protein 2 after transient cerebral ischaemia in the rat

1994 • 9 citations