The Lymphatics Revisited New Perspectives from the Hyaluronan Receptor LYVE-1

LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan

1999 • 1,519 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1

2002 • 993 citations

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

2001 • 957 citations

Lymphatic Metastasis in the Absence of Functional Intratumor Lymphatics

2002 • 939 citations

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

2002 • 894 citations

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

2001 • 816 citations

Molecular mechanisms of lymphangiogenesis in health and disease

2002 • 709 citations

Hyaluronan‐binding proteins in development, tissue homeostasis, and disease

1993 • 656 citations

Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.

2001 • 648 citations

Inflammatory Chemokine Transport and Presentation in HEV

2001 • 532 citations

Isolation and Characterization of Dermal Lymphatic and Blood Endothelial Cells Reveal Stable and Functionally Specialized Cell Lineages

2001 • 516 citations

Hyaluronan: a multifunctional, megaDalton, stealth molecule

2000 • 513 citations

Suppression of Tumor Lymphangiogenesis and Lymph Node Metastasis by Blocking Vascular Endothelial Growth Factor Receptor 3 Signaling

2002 • 512 citations

Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis.

1997 • 496 citations

Mouse LYVE-1 Is an Endocytic Receptor for Hyaluronan in Lymphatic Endothelium

2001 • 469 citations

Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation.

2000 • 466 citations

LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis.

2001 • 439 citations

Vascular Growth Factors and Lymphangiogenesis

2002 • 412 citations

Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer.

2002 • 411 citations

Oligosaccharides of Hyaluronan Are Potent Activators of Dendritic Cells

2000 • 386 citations

The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature

2002 • 371 citations

The Ccr7 Ligand ELC (Ccl19) Is Transcytosed in High Endothelial Venules and Mediates T Cell Recruitment

2001 • 367 citations

Lymphangiogenesis and tumor metastasis: myth or reality?

2001 • 364 citations

LYVE-1, the lymphatic system and tumor lymphangiogenesis

2001 • 348 citations

Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages.

1993 • 330 citations

Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages.

1996 • 323 citations

Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion.

1998 • 314 citations

Solution Structure of the Link Module: A Hyaluronan-Binding Domain Involved in Extracellular Matrix Stability and Cell Migration

1996 • 313 citations

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues

2002 • 275 citations

Identification of the Hyaluronan Receptor for Endocytosis (HARE)

2000 • 255 citations

Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells.

1999 • 246 citations

VEGF‐C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF‐7 tumors

2002 • 241 citations

Hyaluronan Enters Keratinocytes by a Novel Endocytic Route for Catabolism

2001 • 239 citations

Cloning and Characterization of a Novel Promiscuous Human β-Chemokine Receptor D6

1997 • 229 citations

Lymphatic endothelium: a new frontier of metastasis research

2002 • 229 citations

Lymphatic vessels in vascularized human corneas: immunohistochemical investigation using LYVE-1 and podoplanin.

2002 • 223 citations

Lymphangiogenesis and lymphangiodysplasia: From molecular to clinical lymphology

2001 • 222 citations

Turnover and Metabolism of Hyaluronan

2007 • 206 citations

Hepatic Expression of Secondary Lymphoid Chemokine (CCL21) Promotes the Development of Portal-Associated Lymphoid Tissue in Chronic Inflammatory Liver Disease

2002 • 161 citations

Mannose Receptor Is a Novel Ligand for L-Selectin and Mediates Lymphocyte Binding to Lymphatic Endothelium

2001 • 160 citations

TNF-α Induction of CD44-Mediated Leukocyte Adhesion by Sulfation

1998 • 146 citations

Molecular organization, structural features, and ligand binding characteristics of CD44, a highly variable cell surface glycoprotein with multiple functions

2000 • 144 citations

Intratumoral Lymphatic Vessels: A Case of Mistaken Identity or Malfunction?

2002 • 137 citations

Pediatric Lymphangiomas of the Head and Neck

2000 • 137 citations

Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity.

1998 • 103 citations

A role for the cell adhesion molecule CD44 and sulfation in leukocyte–endothelial cell adhesion during an inflammatory response?

2000 • 88 citations

Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies.

1993 • 86 citations

Molecular regulation of lymphangiogenesis and targets for tissue oedema

2001 • 86 citations

The structure and regulation of hyaluronan-binding proteins

1999 • 84 citations

Lymphatic endothelial regulation, lymphoedema, and lymph node metastasis

2002 • 80 citations

Increased nuchal translucency is associated with jugular lymphatic distension

2002 • 76 citations

Changes in Hyaluronan Concentration in Tissues and Body Fluids in Disease States

2007 • 52 citations

Tumour-associated Hyaluronan: A Potential Regulator of Tumour Angiogenesis

1991 • 28 citations

Understanding Hyaluronan-Protein Interactions

2001 • 8 citations

NOVEL ENDOTHELIAL HYALURONAN RECEPTORS

2002 • 3 citations

Deleted Work

1955 • 0 citations