Solution Structure of the Link Module: A Hyaluronan-Binding Domain Involved in Extracellular Matrix Stability and Cell Migration

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Investigation of exchange processes by two-dimensional NMR spectroscopy

1979 • 4,720 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Two-dimensional spectroscopy. Application to nuclear magnetic resonance

1976 • 3,023 citations

Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy

1983 • 2,638 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Proteoglycans: many forms and many functions

1992 • 1,183 citations

Analysis and prediction of the different types of β-turn in proteins

1988 • 962 citations

Structure of a C-type mannose-binding protein complexed with an oligosaccharide

1992 • 873 citations

Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins

1981 • 754 citations

Hyaluronan‐binding proteins in development, tissue homeostasis, and disease

1993 • 656 citations

Multiple domains of the large fibroblast proteoglycan, versican.

1989 • 646 citations

A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins

1989 • 568 citations

Aggregation of Cartilage Proteoglycans

1974 • 567 citations

CD44 — A molecule involved in leukocyte adherence and T-cell activation

1989 • 559 citations

Cartilage proteoglycans

2001 • 557 citations

Structure of the Calcium-Dependent Lectin Domain from a Rat Mannose-Binding Protein Determined by MAD Phasing

1991 • 547 citations

A strategy for the rapid multiple alignment of protein sequences

1987 • 482 citations

Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression

1994 • 436 citations

CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway.

1996 • 421 citations

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

1994 • 397 citations

Aggregation of Cartilage Proteoglycans

1974 • 393 citations

Identification of a common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD44 and link protein.

1994 • 384 citations

Identification of hyaluronic acid binding sites in the extracellular domain of CD44

1993 • 370 citations

Complete primary structure of the rat cartilage proteoglycan core protein deduced from cDNA clones.

1987 • 367 citations

The crystal structure of pertussis toxin

1994 • 343 citations

Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain.

1992 • 330 citations

The FSSP database of structurally aligned protein fold families.

1994 • 323 citations

Atomic features of protein-carbohydrate interactions

1991 • 305 citations

Interaction of cartilage proteoglycans with hyaluronic acid

1977 • 303 citations

Helix stop signals in proteins and peptides: The capping box

1993 • 297 citations

A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.

1992 • 295 citations

Anti-CD44 treatment abrogates tissue aedema and leukocyte infiltration in murine arthrtis

1995 • 283 citations

Lectin-carbohydrate complexes of plants and animals: an atomic view

1993 • 280 citations

New methods for the measurement of NHCαH coupling constants in 15N-labeled proteins

1990 • 262 citations

Rules for α-Helix Termination by Glycine

1994 • 261 citations

Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil

1994 • 244 citations

Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family

1994 • 239 citations

TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivo.

1996 • 214 citations

Cartilage proteoglycans. Structure and heterogeneity of the protein core and the effects of specific protein modifications on the binding to hyaluronate

1976 • 209 citations

A database of protein structure families with common folding motifs

1992 • 208 citations

Measurement of an adhesion molecule as an indicator of inflammatory disease activity: Up‐regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis

1991 • 190 citations

Binding of oligosaccharides of hyaluronic acid to proteoglycans (Short Communication)

1973 • 180 citations

Toward complete 1H NMR spectra in proteins

1988 • 154 citations

TSG-6: a TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis.

1993 • 150 citations

Cartilage proteoglycans. Assembly with hyaluronate and link protein as studied by electron microscopy

1988 • 148 citations

The link proteins

1993 • 143 citations

Effects of detergent solubilization on the hyaluronate-binding protein from membranes of simian virus 40-transformed 3T3 cells.

1983 • 141 citations

The tandemly repeated sequences of cartilage link protein contain the sites for interaction with hyaluronic acid.

1987 • 136 citations

Monoclonal antibodies to CD44 and their influence on hyaluronan recognition.

1995 • 129 citations

The primary structure of link protein from rat chondrosarcoma proteoglycan aggregate.

1986 • 123 citations

An Elisa Plate Based Assay for Hyaluronan Using Biotinylated Proteoglycan G1 Domain (HA-Binding Region)

1990 • 118 citations

Link protein is ubiquitously expressed in non-cartilaginous tissues where it enhances and stabilizes the interaction of proteoglycans with hyaluronic acid.

1994 • 104 citations

Two-dimensional spectroscopy

1997 • 103 citations

Immunoglobulin fold and tandem repeat structures in proteoglycan N-terminal domains and link protein

1989 • 100 citations

A Single Amino Acid Residue Can Determine the Ligand Specificity of E-selectin

1995 • 91 citations

Cell surface P- and E-selectin support shear-dependent rolling of bovine gamma/delta T cells.

1994 • 77 citations

Interaction of cartilage proteoglycans with hyaluronic acid. The role of the hyaluronic acid carboxyl groups

1977 • 61 citations

Overexpression, Purification, and Refolding of Link Module from Human TSG-6 inEscherichia coli:Effect of Temperature, Media, and Mutagenesis on Lysine Misincorporation at Arginine AGA Codons

1996 • 53 citations

Evidence of a defined spatial arrangement of hyaluronate in the central filament of cartilage proteoglycan aggregates

1995 • 51 citations

Tertiary Structure of Erabutoxin b in Aqueous Solution as Elucidated by Two-dimensional Nuclear Magnetic Resonance

1994 • 50 citations

TSG‐6 expression in human articular chondrocytes: Possible implications in joint inflammation and cartilage degradation

1996 • 47 citations

Biotinylated Hyaluronic Acid: A New Tool for Probing Hyaluronate-Receptor Interactions

1994 • 44 citations

Biotinylated hyaluronan as a probe for detection of binding proteins in cells and tissues.

1995 • 43 citations

The expression of functional link protein in a baculovirus system: analysis of mutants lacking the A, B and B' domains

1994 • 37 citations

Specific chemical modifications of link protein and their effect on binding to hyaluronate and cartilage proteoglycan

1986 • 26 citations

Estimation of Interatomic Distances in Proteins from NOE Spectra at Longer Mixing Times Using an Empirical Two-Spin Equation

1993 • 13 citations

Expression and Characterization of a Single Recombinant Proteoglycan Tandem Repeat Domain of Link Protein That Binds Zinc and Hyaluronate

1995 • 10 citations