Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation.

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

1995 • 1,421 citations

Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

1997 • 1,280 citations

Solid stress inhibits the growth of multicellular tumor spheroids

1997 • 801 citations

Delivery of Novel Therapeutic Agents in Tumors: Physiological Barriers and Strategies

1989 • 571 citations

VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer

1999 • 550 citations

Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

1996 • 406 citations

Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human Tumors

1998 • 328 citations

Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3.

1998 • 315 citations

Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer.

1999 • 313 citations

Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors

1999 • 296 citations

Expression of the Vascular Endothelial Growth Factor C Receptor VEGFR-3 in Lymphatic Endothelium of the Skin and in Vascular Tumors

1998 • 206 citations

Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory

1996 • 137 citations

Proliferation of lymphatics in inflammation

1937 • 88 citations

Transport in lymphatic capillaries. II. Microscopic velocity measurement with fluorescence photobleaching

1996 • 87 citations

Flow velocity in the superficial lymphatic network of the mouse tail

1994 • 80 citations

Experimental studies on the spread of cancer in the lymphatic system. III. Tumor emboli in thoracic duct; the pathogenesis of Virchow's node.

1955 • 71 citations

Experimental studies on the spread of cancer in the lymphatic system.II. Absence of a lymphatic supply in carcinoma

1955 • 60 citations

Experimental study on lymphatic vascular changes in the development of cancer.

1981 • 34 citations

SURGICAL MANAGEMENT OF ADVANCED CANCER OF THE BREAST

1950 • 22 citations

LYMPH VESSELS IN RABBIT CARCINOMA

1933 • 11 citations

Angiogenesis, Tumor Vascularization, and Potential Interference with Tumor Growth

1985 • 6 citations