Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)

Apoptosis by Death Factor

1997 • 5,038 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

1997 • 2,284 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Phosphorylation of c-jun mediated by MAP kinases

1991 • 1,495 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

TNF-Dependent Recruitment of the Protein Kinase RIP to the TNF Receptor-1 Signaling Complex

1996 • 1,154 citations

Two TNF receptors

1992 • 1,048 citations

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1998 • 985 citations

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1994 • 978 citations

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1997 • 791 citations

Identification of a Dual Specificity Kinase That Activates the Jun Kinases and p38-Mpk2

1995 • 775 citations

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1994 • 706 citations

ASK1 Is Essential for JNK/SAPK Activation by TRAF2

1998 • 641 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by the Adapter Protein Daxx

1998 • 596 citations

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme.

1994 • 596 citations

Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1997 • 552 citations

The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases

1997 • 507 citations

Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region

1996 • 484 citations

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1995 • 454 citations

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH ₂ -terminal kinase

1997 • 382 citations

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1998 • 351 citations

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.

1996 • 339 citations

Anatomy of TRAF2

1996 • 302 citations

Tumor Necrosis Factor Signaling to Stress-activated Protein Kinase (SAPK)/Jun NH2-terminal Kinase (JNK) and p38

1998 • 267 citations

A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses

1997 • 258 citations

Modularity in the TNF-receptor family

1998 • 250 citations

A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.

1996 • 250 citations

MEK Kinase 1, a Substrate for DEVD-Directed Caspases, Is Involved in Genotoxin-Induced Apoptosis

1998 • 236 citations

Ordering the Cell Death Pathway

1996 • 231 citations

Presence of a New Conserved Domain in CART1, a Novel Member of the Tumor Necrosis Factor Receptor-associated Protein Family, Which Is Expressed in Breast Carcinoma

1995 • 229 citations

JNK or IKK, AP-1 or NF-κB, which are the targets for MEK kinase 1 action?

1998 • 217 citations

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

1995 • 214 citations

MKK7 Is A Stress-activated Mitogen-activated Protein Kinase Kinase Functionally Related to hemipterous

1997 • 182 citations

Molecular Cloning and Characterization of a Novel Protein Kinase with a Catalytic Domain Homologous to Mitogen-activated Protein Kinase Kinase Kinase

1996 • 149 citations

Molecular, structural, and biological characteristics of the tumor necrosis factor ligand superfamily

1996 • 125 citations

Tumor Necrosis Factor (TNF) Receptor 1 Signaling Downstream of TNF Receptor-associated Factor 2

1997 • 117 citations

Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.

1992 • 109 citations

Activation of Stress-activated Protein Kinases/c-Jun N-terminal Protein Kinases (SAPKs/JNKs) by a Novel Mitogen-activated Protein Kinase Kinase (MKK7)

1997 • 100 citations

Novel components of mammalian stress-activated protein kinase cascades

1997 • 9 citations