A Role for Transcriptional Repressors in Targeting the Yeast Swi/Snf Complex

Methods in yeast genetics

1979 • 7,824 citations

Current protocols in molecular biology

1988 • 7,584 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION

1998 • 1,124 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

1996 • 830 citations

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

1993 • 795 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

Diversity and specialization of mammalian SWI/SNF complexes.

1996 • 703 citations

RSC, an Essential, Abundant Chromatin-Remodeling Complex

1996 • 680 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

1992 • 567 citations

GENES AFFECTING THE REGULATION OF SUC2 GENE EXPRESSION BY GLUCOSE REPRESSION IN SACCHAROMYCES CEREVISIAE

1984 • 567 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

1998 • 507 citations

THE REGULATION OF HISTONE SYNTHESIS IN THE CELL CYCLE

1991 • 498 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

Formaldehyde-mediated DNA-protein crosslinking: a probe for in vivo chromatin structures.

1985 • 440 citations

Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

1994 • 410 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Mapping polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin

1993 • 360 citations

A SWI/SNF–Related Chromatin Remodeling Complex, E-RC1, Is Required for Tissue-Specific Transcriptional Regulation by EKLF In Vitro

1998 • 307 citations

The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation.

1993 • 299 citations

RB and hbrm cooperate to repress the activation functions of E2F1

1997 • 293 citations

Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State

1998 • 283 citations

Functional Interactions between the hBRM/hBRG1 Transcriptional Activators and the pRB Family of Proteins

1996 • 252 citations

A SUPPRESSOR OF snf1 MUTATIONS CAUSES CONSTITUTIVE HIGH-LEVEL INVERTASE SYNTHESIS IN YEAST

1984 • 228 citations

Persistent Site-Specific Remodeling of a Nucleosome Array by Transient Action of the SWI/SNF Complex

1996 • 227 citations

The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.

1995 • 225 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae.

1990 • 207 citations

Identification of sequences in a yeast histone promoter involved in periodic transcription

1986 • 207 citations

DNA-binding properties of the yeast SWI/SNF complex

1996 • 195 citations

The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.

1994 • 190 citations

A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

1995 • 188 citations

Catalytic activity of the yeast SWI/SNF complex on reconstituted nucleosome arrays

1997 • 184 citations

A functional interaction between the C-terminal domain of RNA polymerase II and the negative regulator SIN1

1991 • 176 citations

Chromatin remodeling machines: similar motors, ulterior motives

1998 • 175 citations

Budding yeast centromere composition and assembly as revealed by in vivo cross-linking

1997 • 173 citations

Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes

1998 • 168 citations

Hir Proteins Are Required for Position-Dependent Gene Silencing in Saccharomyces cerevisiae in the Absence of Chromatin Assembly Factor I

1998 • 167 citations

HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3

1998 • 165 citations

Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2

1997 • 160 citations

Glucocorticoid Receptor-Glucocorticoid Response Element Binding Stimulates Nucleosome Disruption by the SWI/SNF Complex

1997 • 159 citations

A Negative Regulator of HO Transcription, SIN1 (SPT2), Is a Nonspecific DNA-Binding Protein Related to HMG1

1991 • 157 citations

Mutations Causing Constitutive Invertase Synthesis in Yeast: Genetic Interactions with snf Mutations

1987 • 149 citations

Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae.

1993 • 146 citations

Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2

1996 • 144 citations

The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes.

1990 • 144 citations

Hir1p and Hir2p Function as Transcriptional Corepressors To Regulate Histone Gene Transcription in the Saccharomyces cerevisiae Cell Cycle

1997 • 134 citations

RNA Polymerase II Holoenzyme Recruitment Is Sufficient to Remodel Chromatin at the Yeast PHO5 Promoter

1997 • 133 citations

Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes.

1987 • 126 citations

Molecular analysis of SNF2 and SNF5, genes required for expression of glucose-repressible genes in Saccharomyces cerevisiae.

1986 • 123 citations

A human homolog of the S.cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region

1995 • 121 citations

Chromatin remodeling: a marriage between two families?

1998 • 108 citations

Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA

1998 • 105 citations

The SNF2, SNF5 and SNF6 genes are required for Ty transcription in Saccharomyces cerevisiae.

1991 • 97 citations

Chromatin-mediated transcription repression in yeast

1995 • 94 citations

SWI/SNF Stimulates the Formation of Disparate Activator-Nucleosome Complexes but Is Partially Redundant with Cooperative Binding

1997 • 86 citations

Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae.

1992 • 84 citations

Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure

1997 • 78 citations

A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1.

1991 • 77 citations

Role of transcriptional and posttranscriptional regulation in expression of histone genes in Saccharomyces cerevisiae.

1987 • 75 citations

Mutations in both the structured domain and N-terminus of histone H2B bypass the requirement for Swi-Snf in yeast

1999 • 70 citations

SNF6 encodes a nuclear protein that is required for expression of many genes in Saccharomyces cerevisiae.

1990 • 68 citations

Formaldehyde cross-linking and immunoprecipitation demonstrate developmental changes in H1 association with transcriptionally active genes.

1991 • 68 citations

Evidence that Snf-Swi controls chromatin structure over both the TATA and UAS regions of the SUC2 promoter in Saccharomyces cerevisiae

1997 • 64 citations

The Effect of Histone Gene Deletions on Chromatin Structure in Saccharomyces cerevisiae

1988 • 61 citations

A yeast H2A-H2B promoter can be regulated by changes in histone gene copy number.

1990 • 57 citations

Yeast Ty1 Retrotransposition Is Stimulated by a Synergistic Interaction between Mutations in Chromatin Assembly Factor I and Histone Regulatory Proteins

1998 • 57 citations

Coding and Noncoding Sequences at the 3′ End of Yeast Histone H2B mRNA Confer Cell Cycle Regulation

1990 • 43 citations

Functional Analysis of Histones H2A and H2B in Transcriptional Repression in Saccharomyces cerevisiae

1996 • 41 citations

Functional Dissection of Yeast Hir1p, a WD Repeat–Containing Transcriptional Corepressor

1998 • 39 citations

The C-Terminal Domain of Sin1 Interacts with the SWI-SNF Complex in Yeast

1998 • 25 citations

The HIR4-1 mutation defines a new class of histone regulatory genes in Saccharomyces cerevisiae.

1993 • 18 citations