Hir Proteins Are Required for Position-Dependent Gene Silencing in Saccharomyces cerevisiae in the Absence of Chromatin Assembly Factor I

Crystal structure of the nucleosome core particle at 2.8 Å resolution

1997 • 8,906 citations

Methods in yeast genetics

1979 • 7,824 citations

Histone acetylation in chromatin structure and transcription

1997 • 2,834 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

1990 • 1,343 citations

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast

1995 • 778 citations

Four Genes Responsible for a Position Effect on Expression From HML and HMR in Saccharomyces cerevisiae

1987 • 709 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.

1997 • 673 citations

Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro

1989 • 667 citations

Nucleosome Assembly by a Complex of CAF-1 and Acetylated Histones H3/H4

1996 • 624 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

Chromatin

1989 • 606 citations

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

1992 • 567 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

The Major Cytoplasmic Histone Acetyltransferase in Yeast: Links to Chromatin Replication and Histone Metabolism

1996 • 429 citations

Intermediates of recombination during mating type switching in Saccharomyces cerevisiae.

1990 • 405 citations

Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.

1997 • 382 citations

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1990 • 376 citations

The p150 and p60 subunits of chromatin assemblyfactor I: A molecular link between newly synthesized histories and DNA replication

1995 • 373 citations

Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.

1990 • 350 citations

Genetic Analysis of Histone H4: Essential Role of Lysines Subject to Reversible Acetylation

1990 • 346 citations

Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase

1998 • 344 citations

Yeast histone H4 N-terminal sequence is required for promoter activation in vivo

1991 • 330 citations

Epigenetic inheritance of transcriptional states in S. cerevisiae

1989 • 327 citations

Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission

1986 • 322 citations

Cloning and characterization of four SIR genes of Saccharomyces cerevisiae.

1986 • 305 citations

Stepwise assembly of chromatin during DNA replication in vitro.

1991 • 293 citations

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

1993 • 283 citations

Changes in histone gene dosage alter transcription in yeast.

1988 • 275 citations

Saccharomyces telomeres assume a non-nucleosomal chromatin structure.

1992 • 275 citations

Two complexes that contain histones are required for nucleosome assembly in vitro: Role of nucleoplasmin and N1 in Xenopus egg extracts

1987 • 271 citations

Chromatin assembly during SV40 DNA replication in vitro

1986 • 262 citations

Drosophila NAP-1 Is a Core Histone Chaperone That Functions in ATP-Facilitated Assembly of Regularly Spaced Nucleosomal Arrays

1996 • 253 citations

SET1, A Yeast Member of theTrithoraxFamily, Functions in Transcriptional Silencing and Diverse Cellular Processes

1997 • 238 citations

Silencers and Domains of Generalized Repression

1994 • 233 citations

Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo.

1992 • 227 citations

Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast

1994 • 227 citations

Effects of histone H4 depletion on the cell cycle and transcription of Saccharomyces cerevisiae.

1988 • 225 citations

Co-existence of two different types of soluble histone complexes in nuclei of Xenopus laevis oocytes.

1985 • 210 citations

Identification of sequences in a yeast histone promoter involved in periodic transcription

1986 • 207 citations

Silencing and Heritable Domains of Gene Expression

1995 • 196 citations

Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci

1998 • 196 citations

Active genes in budding yeast display enhanced in vivo accessibility to foreign DNA methylases: a novel in vivo probe for chromatin structure of yeast.

1992 • 188 citations

Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.

1992 • 186 citations

Notes: Point Mutations in the Yeast Histone H4 Gene Prevent Silencing of the Silent Mating Type Locus HML

1990 • 168 citations

Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

1987 • 164 citations

Histones in Transit: Cytosolic Histone Complexes and Diacetylation of H4 During Nucleosome Assembly in Human Cells

1997 • 158 citations

RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo.

1997 • 147 citations

Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae.

1993 • 146 citations

Hir1p and Hir2p Function as Transcriptional Corepressors To Regulate Histone Gene Transcription in the Saccharomyces cerevisiae Cell Cycle

1997 • 134 citations

The Role of Sas2, an Acetyltransferase Homologue of Saccharomyces cerevisiae, in Silencing and ORC Function

1997 • 134 citations

The p55 Subunit of Drosophila Chromatin Assembly Factor 1 Is Homologous to a Histone Deacetylase-Associated Protein

1996 • 130 citations

The yeast Cac1 protein is required for the stable inheritance of transcriptionally repressed chromatin at telomeres

1997 • 127 citations

Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes.

1987 • 126 citations

A human homolog of the S.cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region

1995 • 121 citations

MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae.

1989 • 111 citations

A New Class of Histone H2A Mutations in Saccharomyces cerevisiae Causes Specific Transcriptional Defects In Vivo

1995 • 108 citations

Epigenetic Switching of Transcriptional States: cis- and trans-Acting Factors Affecting Establishment of Silencing at the HMR Locus in Saccharomyces cerevisiae

1993 • 94 citations

Postreplicative Chromatin Assembly by Drosophila and Human Chromatin Assembly Factor 1

1996 • 93 citations

All four core histone N-termini contain sequences required for the repression of basal transcription in yeast.

1996 • 90 citations

SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae.

1994 • 88 citations

Cloning and Characterization of Four SIR Genes of Saccharomyces cerevisiae

1986 • 88 citations

Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae.

1992 • 73 citations

A yeast H2A-H2B promoter can be regulated by changes in histone gene copy number.

1990 • 57 citations

Yeast Ty1 Retrotransposition Is Stimulated by a Synergistic Interaction between Mutations in Chromatin Assembly Factor I and Histone Regulatory Proteins

1998 • 57 citations

Nucleosome assembly: the CAF and the HAT

1996 • 53 citations

Chromatin: Nucleosome assembly during DNA replication

1995 • 53 citations

Amino Termini of Histones H3 and H4 Are Required for a1-α2 Repression in Yeast

1997 • 50 citations

Histone regulatory (hir) mutations suppress delta insertion alleles in Saccharomyces cerevisiae.

1991 • 49 citations

The products of the SPT10 and SPT21 genes of Saccharomyces cerevisiae increase the amplitude of transcriptional regulation at a large number of unlinked loci.

1991 • 46 citations

Characterization of HIR1 and HIR2, Two Genes Required for Regulation of Histone Gene Transcription in Saccharomyces cerevisiae

1993 • 45 citations

Functional Analysis of Histones H2A and H2B in Transcriptional Repression in Saccharomyces cerevisiae

1996 • 41 citations

SPT10 and SPT21 Are Required for Transcription of Particular Histone Genes in Saccharomyces cerevisiae

1994 • 32 citations

trans-Acting Regulatory Mutations That Alter Transcription of Saccharomyces cerevisiae Histone Genes

1987 • 31 citations